Ascending Single-Dose, Double-Blind, Placebo-Controlled Safety Study of Noribogaine in Opioid-Dependent Patients

Autor: Michelle Marie Lockhart, Holger Weis, Donna Tunnicliff, Sarah Harland, Borje Darpo, Jane Devane, R. S. Crockett, Gavin Cape, John Howes, C. Tak Hung, Meijian Zhou, Lawrence Friedhoff, Noelyn Hung, Fred Lam, Paul Glue

Publikováno v: Clinical Pharmacology in Drug Development. 5:460-468

Ibogaine is a psychoactive substance that may reduce opioid withdrawal symptoms. This was the first clinical trial of noribogaine, ibogaine's active metabolite, in patients established on methadone opioid substitution therapy (OST). In this randomize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d307c2c1237945aa226f0b88e893451a
https://doi.org/10.1002/cpdd.254

List of Contributors

Autor: Ricardo Abadie-Guedes, Anissa Abi-Dargham, Osama A. Abulseoud, Jelena Acevska, Ana Adan, María A. Aguilar, Maryam Akhgari, Robert Ali, Amelia J. Anderson-Mooney, Muhammad Anees, M. Carmen Arenas, Jamie Arndt, Daniele Ascheri, Nida Ashraf, Maxie Ashton, Olga Asimaki, Jean-Michel Aubry, Harinder Aujla, A. George Awad, Mahmoud A. Awara, Ana Bagues, Yatan P.S. Balhara, Francis Bambico, Laura Barrio-Real, Selena E. Bartlett, Balapal S. Basavarajappa, Aniruddha Basu, Claiton H.D. Bau, Matthew C. Beattie, Benjamin Becker, Anton L. Beer, Deepak Behera, Irina Benaiges, Dessa Bergen-Cico, Susan E. Bergeson, Wade H. Berrettini, Leandro J. Bertoglio, Charles S. Bockman, Stefan Borgwardt, Josiane Bourque, Muge Bozkurt, Katharine Alexandra Brennan, Hilary Briggs, Samanth J. Brooks, Rachel Picada Bulcão, Ute Burkhardt, Tracy R. Butler, Eduardo Rodrigues Cabrera, Daniela Caldirola, Russell C. Callaghan, Elza Callegari, María J. Caloca, Alline C. Campos, Carla Cannizzaro, Gavin Cape, Benjamin L. Carnell, Javier R. Caso, Lucas Henrique Cendron, Yun-Hsuan Chang, Gordon L.F. Cheng, Kao Chin Chen, Kanwaljit Chopra, Tony C.H. Chow, Rachael Cico, Jason B. Cook, Maurizio Coppola, Jose A. Cortes-Briones, Janna Cousijn, Richard C. Crist, Candice E. Crocker, Kirsty Danielson, Miguel Dasilva, Malay Dave, Mariella De Biasi, Cristiane R. de Carvalho, François De Guio, Dirk De Ridder, Sonia Dhiman, Giuseppina Diaferia, Marco Diana, Joseph R. DiFranza, Aneta Dimitrovska, Le-Anh Dinh-Williams, Maja Djurendic-Brenesel, Jonathan N. Dodd, Neil C. Dodge, Paul D. Drew, Rene Drucker Colín, Irena Dujmovic, Marcelo Dutra Arbo, Scott Edwards, Afshar Etemadi-Aleagha, Cuneyt Evren, Juan Fang, Camino Fernández-Rodríguez, Radmila Filipovic, Josef Finsterer, Megan L. Fitzgerald, Manoela V. Fogaça, Diego A. Forero, Hamdy Fouad Moselhy, Marco Antonio de Freitas, Cherrie Galletly, Borja García-Bueno, Jodi M. Gatley, David Germanaud, Roger S. Gifford, Paul Glue, Gabriella Gobbi, Carlos Goicoechea, Emilio González-Arnay, Emilio González-Reimers, Rogelio González-Sarmiento, Linda Gowing, Kenneth L. Grieve, Rubem Carlos Araújo Guedes, Consuelo Guerri, Francisco S. Guimarães, Leila Guller, Jennifer Harland, Seyyed A. Hashemi, Shiva Hashemizadeh, Bei He, Salvador Hernández-López, Tyson Hickle, Shirley Y. Hill, Joan Holgate, Wei Huang, Wei-Lieh Huang, Nicholas J. Hunt, René Hurlemann, Giuseppe Iannone, Fariha Idrees, Jawaria Idrees, Kazutaka Ikeda, Nato Ivanashvili, Iliyan Ivanov, Joseph L. Jacobson, Sandra W. Jacobson, Torbjörn U.C. Järbe, Y.L. Jiang, Farzaneh Jokar, Cynthia J.M. Kane, Megan Kangiser, Victor Karpyak, Jean A. King, Bronwyn M. Kivell, Eugene A. Kiyatkin, Jochen Klein, Michelle L. Klima, Sodikdjon A. Kodirov, Michal Korostynski, Mary Jeanne Kreek, Svetlana Kulevanova, Santosh Kumar, Berthold Langguth, Mirna Bainy Leal, Sheng-Yu Lee, Tatia M.C. Lee, John Leikaif, Shih-Hsien Lin, Yu-Hsuan Lin, Xiu Liu, Valentina Lorenzetti, Ru-Band Lu, Rita Machaalani, Antoniette Maldonado-Devincci, Jean-François Mangin, Dimitra Mangoura, Patrick Manning, Jahan P. Marcu, Simon McCabe, M. Adrienne McGinn, Diana L. McKinney, Ryan McLaughin, Ian McLaughlin, Ernesta Meintjes, Narasimha M. Midde, Stefan Mihailescu, José Miñarro, Raffaella Mondola, A. Leslie Morrow, Nina R. Mota, Jeffrey Newcorn, Daisuke Nishizawa, José N. Nobrega, Christina N. Nona, Nicolas Nuñez, Ingrid Nylander, Jessica W. O’Brien, Francesco Oliva, Sara Palm, Mauricio R. Papini, Byung Lae Park, María Pascual, Juan Pedraza, Giampaolo Perna, Rocco Luigi Picci, Marcin Piechota, Vladimir Pilija, Charles Pinto, Stéphane Potvin, Jagdeo Prasad Rawat, Victor R. Preedy, Brittany M. Priddy, Ryszard Przewlocki, Jimit G. Raghav, Rajkumar Rajendram, Roshanna Rajendram, P.S.S. Rao, Anirban Ray, Ameneh Rezayof, Casto Rivadulla, Marta Rodríguez-Arias, Luciana Grazziotin Rossato, Diego L. Rovaris, Christina L. Ruby, Nikos Sakellaridis, Saad Salman, Francisco Santolaria-Fernández, Siddharth Sarkar, Jason B. Schechter, André Schmidt, Susan Scholl, April Scott, Masroor Shariff, Shiwali Sharma, Hyoung Doo Shin, Thakur Gurjeet Singh, Namita Sinha, Patrick D. Skosnik, Ranilson de Souza Bezerra, Dustin J. Stairs, Gjoshe Stefkov, Dan J. Stein, Cristina A.J. Stern, Claudia Stöllberger, Reinaldo N. Takahashi, H.C. Tang, Josephine Tarren, Philip G. Tibbo, Vinod Tiwari, Carmen Torres, Federica Trivelli, Penelope Truman, Emmanouella Tsirimonaki, Sven Vanneste, Andrea R. Vansickel, Leandro F. Vendruscolo, Maria S.M. Wai, Marc Walter, Karen A. Waters, Jeffrey L. Weiner, Jodi J. Weinstein, Jordyn Weisberg, Annie M. Whitaker, Sarah Wolf-Stanton, Chen-Ying Wu, Sharon L. Wu, Cheryl C.H. Yang, Yen Kuang Yang, Kirti Yeshwant Tandel, D.T. Yew, Yashar Yousefzadeh Fard, Yan Zhou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fcf12b9446119863402c7acf45328e6e
https://doi.org/10.1016/b978-0-12-800213-1.01002-6

Ascending Single-Dose, Double-Blind, Placebo-Controlled Safety Study of Noribogaine in Opioid-Dependent Patients

Autor: Paul, Glue, Gavin, Cape, Donna, Tunnicliff, Michelle, Lockhart, Fred, Lam, Noelyn, Hung, C Tak, Hung, Sarah, Harland, Jane, Devane, R S, Crockett, John, Howes, Borje, Darpo, Meijian, Zhou, Holger, Weis, Lawrence, Friedhoff

Publikováno v: Clinical pharmacology in drug development. 5(6)

Ibogaine is a psychoactive substance that may reduce opioid withdrawal symptoms. This was the first clinical trial of noribogaine, ibogaine's active metabolite, in patients established on methadone opioid substitution therapy (OST). In this randomize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9118ba2bcaa394fb681bac4cf81e90ed
https://pubmed.ncbi.nlm.nih.gov/27870477

Addiction, stigma and movies

Autor: Gavin Cape

Publikováno v: Acta Psychiatrica Scandinavica. 107:163-169

Objective: To identify common character stereotypes of alcohol and other drug users as portrayed in motion pictures. Method: A selective review of a number of movies prominently portraying alcohol and other drug use and misuse. Results: The great maj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c366ab604b9aeb071910644f19e1ca4
https://doi.org/10.1034/j.1600-0447.2003.00075.x

Movies as a vehicle to teach addiction medicine

Autor: Gavin Cape

Publikováno v: International review of psychiatry (Abingdon, England). 21(3)

Dependence on a substance and the role of medical practitioners in this health problem can be perceived as an enigma. Movies, as a tool for teaching, can be a powerful means of engaging, clarifying and educating students within the addiction medicine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be8a656855e425ddb5a0c29c6971f3e
https://pubmed.ncbi.nlm.nih.gov/19459096