Late-onset and long-lasting immune-related adverse events from immune checkpoint-inhibitors: An overlooked aspect in immunotherapy

Autor: Ghisoni, E., Wicky, A., Bouchaab, H., Imbimbo, M., Delyon, J., Gautron Moura, B., Gérard, C.L., Latifyan, S., Özdemir, B.C., Caikovski, M., Pradervand, S., Tavazzi, E., Gatta, R., Marandino, L., Valabrega, G., Aglietta, M., Obeid, M., Homicsko, K., Mederos Alfonso, N.N., Zimmermann, S., Coukos, G., Peters, S., Cuendet, M.A., Di Maio, M., Michielin, O.

Publikováno v: In European Journal of Cancer May 2021 149:153-164

Safety and Efficacy of Ipilimumab plus Nivolumab and Sequential Selective Internal Radiation Therapy in Hepatic and Extrahepatic Metastatic Uveal Melanoma.

Autor: Aedo-Lopez V; Department of Oncology, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH-1011 Lausanne, Switzerland.; Department of Oncology, Monash Medical Centre, 823-865 Centre Road, East Bentleigh, Melbourne, VIC 3165, Australia., Gérard CL; Precision Oncology Center, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH-1011 Lausanne, Switzerland., Boughdad S; Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH-1011 Lausanne, Switzerland., Gautron Moura B; Department of Oncology, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH-1011 Lausanne, Switzerland., Berthod G; Department of Oncology, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH-1011 Lausanne, Switzerland., Digklia A; Department of Oncology, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH-1011 Lausanne, Switzerland., Homicsko K; Department of Oncology, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH-1011 Lausanne, Switzerland.; Precision Oncology Center, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH-1011 Lausanne, Switzerland., Schaefer N; Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH-1011 Lausanne, Switzerland., Duran R; Department of Radiology and Interventional Radiology, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH-1011 Lausanne, Switzerland., Cuendet MA; Precision Oncology Center, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH-1011 Lausanne, Switzerland.; Molecular Modelling Group, Swiss Institute of Bioinformatics, Quartier Sorge, CH-1015 Lausanne, Switzerland., Michielin O; Department of Oncology, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH-1011 Lausanne, Switzerland.; Precision Oncology Center, Lausanne University Hospital (CHUV), Rue du Bugnon 46, CH-1011 Lausanne, Switzerland.; Molecular Modelling Group, Swiss Institute of Bioinformatics, Quartier Sorge, CH-1015 Lausanne, Switzerland.

Publikováno v: Cancers [Cancers (Basel)] 2022 Feb 24; Vol. 14 (5). Date of Electronic Publication: 2022 Feb 24.

The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study.

Autor: Martins F; Centre Hospitalier Universitaire Vaudois (CHUV), Hematology Service and Central Laboratory, Oncology Department, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland. filipe.martins@epfl.ch.; Swiss Federal Institute of Technology Lausanne (Ecole polytechnique Fédérale de Lausanne, EPFL), School of Life Sciences, Laboratory of Virology and Genetics (LVG), EPFL-SV-GHI-LVG, Station 11, CH-1015, Lausanne, Switzerland. filipe.martins@epfl.ch., Schiappacasse L; Centre Hospitalier Universitaire Vaudois (CHUV), Radio-Oncology Service, Oncology Department, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland., Levivier M; Centre Hospitalier Universitaire Vaudois (CHUV), Neurosurgery Service and Gamma Knife Center, Clinical Neurosciences Department, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland., Tuleasca C; Centre Hospitalier Universitaire Vaudois (CHUV), Neurosurgery Service and Gamma Knife Center, Clinical Neurosciences Department, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.; Swiss Federal Institute of Technology Lausanne (Ecole polytechnique Fédérale de Lausanne, EPFL), Signal Processing Laboratory (LTS5), EPFL-STI-IEL-LTS5, Station 11, CH-1015, Lausanne, Switzerland.; University of Lausanne (UNIL), Faculty of Biology and Medicine (FBM), Rue du Bugnon 21, CH-1005, Lausanne, Switzerland., Cuendet MA; Centre Hospitalier Universitaire Vaudois (CHUV), Precision Oncology Center, Oncology Department, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Weill Cornell Medicine, Department of Physiology and Biophysics, New York, USA., Aedo-Lopez V; Centre Hospitalier Universitaire Vaudois (CHUV), Oncology Service, Oncology Department, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland., Gautron Moura B; Centre Hospitalier Universitaire Vaudois (CHUV), Oncology Service, Oncology Department, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland., Homicsko K; Centre Hospitalier Universitaire Vaudois (CHUV), Oncology Service, Oncology Department, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland., Bettini A; Fribourg Cantonal Hospital (HFR), Internal Medicine Department, Oncology Service, CH-1708, Fribourg, Switzerland., Berthod G; Centre Hospitalier Universitaire Vaudois (CHUV), Oncology Service, Oncology Department, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.; Hospital Center for Valais Romand (CHVR), Martigny Hospital, Avenue de la Fusion 27, CH-1920, Martigny, Switzerland., Gérard CL; Centre Hospitalier Universitaire Vaudois (CHUV), Precision Oncology Center, Oncology Department, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland., Wicky A; Centre Hospitalier Universitaire Vaudois (CHUV), Precision Oncology Center, Oncology Department, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland., Bourhis J; Centre Hospitalier Universitaire Vaudois (CHUV), Radio-Oncology Service, Oncology Department, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland. jean.bourhis@chuv.ch., Michielin O; Centre Hospitalier Universitaire Vaudois (CHUV), Oncology Service, Precision Oncology Center, Oncology Department, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland. olivier.michielin@chuv.ch.

Publikováno v: Journal of neuro-oncology [J Neurooncol] 2020 Jan; Vol. 146 (1), pp. 181-193. Date of Electronic Publication: 2019 Dec 14.

Toxicity-Induced Discontinuation of Immune Checkpoint Inhibitors in Metastatic Urothelial Cancer: 6-Year Experience from a Specialized Uro-Oncology Center.

Autor: Rodler, Severin^1,2,3 (AUTHOR) severin.rodler@med.uni-muenchen.de, Aydogdu, Can^1,2 (AUTHOR), Brinkmann, Isabel^1,2 (AUTHOR), Berg, Elena^1,2 (AUTHOR), Kopliku, Rega¹ (AUTHOR), Götz, Melanie^1,2 (AUTHOR), Ivanova, Troya¹ (AUTHOR), Tamalunas, Alexander^1,2 (AUTHOR), Schulz, Gerald B.¹ (AUTHOR), Heinemann, Volker^2,4 (AUTHOR), Stief, Christian G.^1,2 (AUTHOR), Casuscelli, Jozefina^1,2 (AUTHOR)

Publikováno v: Cancers. Jun2024, Vol. 16 Issue 12, p2246. 10p.

Risk Factors for Immune Checkpoint Inhibitor-Induced Liver Injury and the Significance of Liver Biopsy.

Autor: Kawano, Miki¹ (AUTHOR) kawanom@med.kobe-u.ac.jp, Yano, Yoshihiko¹ (AUTHOR) yama1004@med.kobe-u.ac.jp, Yamamoto, Atsushi¹ (AUTHOR) yuta9130@med.kobe-u.ac.jp, Yasutomi, Eiichiro² (AUTHOR) eiichiro_yasutomi@yahoo.co.jp, Inoue, Yuta¹ (AUTHOR) jkitadai@med.kobe-u.ac.jp, Kitadai, Jun¹ (AUTHOR) yoshidar@med.kobe-u.ac.jp, Yoshida, Ryutaro¹ (AUTHOR) tmatsu@med.kobe-u.ac.jp, Matsuura, Takanori¹ (AUTHOR) yshiomi@med.kobe-u.ac.jp, Shiomi, Yuuki¹ (AUTHOR) yueda@med.kobe-u.ac.jp, Ueda, Yoshihide¹ (AUTHOR) kodama@med.kobe-u.ac.jp, Kodama, Yuzo¹ (AUTHOR)

Publikováno v: Diagnostics (2075-4418). Apr2024, Vol. 14 Issue 8, p815. 12p.