Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Gautam V. Soni"'
Autor:
Serene Rose David, Sumanth Kumar Maheshwaram, Divya Shet, Mahesh B. Lakshminarayana, Gautam V. Soni
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The CRISPR-associated protein 9 (Cas9) system has proven to be a powerful technology for genome editing in a wide variety of in vivo and in vitro applications. CRISPR–Cas9, when loaded with the guide RNA, cleaves the DNA at the target posi
Externí odkaz:
https://doaj.org/article/55cb3d192c104598af89355a07c8f5db
Autor:
Sumanth K. Maheshwaram, Divya Shet, Serene R. David, Mahesh B. Lakshminarayana, Gautam V. Soni
Publikováno v:
ACS Sensors. 7:3876-3884
The location of nucleosomes in DNA and their structural stability are critical in regulating DNA compaction, site accessibility, and epigenetic gene regulation. Here, we combine the nanopore platform-based fast and label-free single-molecule detectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8336b657439dc0e71b23900857bfbab6
https://doi.org/10.1021/acssensors.2c01865
https://doi.org/10.1021/acssensors.2c01865
Autor:
Sumanth K. Maheshwaram, Divya Shet, Serene R. David, Mahesh B. Lakshminarayana, Gautam V. Soni
Publikováno v:
Biophysical Journal. 122:287a-288a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86b9c3664ef9715d7ef77e5fa6fad6ba
https://doi.org/10.1016/j.bpj.2022.11.1632
https://doi.org/10.1016/j.bpj.2022.11.1632
Autor:
Jayesh A Bafna, Gautam V Soni
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157399 (2016)
We show low-cost fabrication and characterization of borosilicate glass nanopores for single molecule sensing. Nanopores with diameters of ~100 nm were fabricated in borosilicate glass capillaries using laser assisted glass puller. We further achieve
Externí odkaz:
https://doaj.org/article/02ea497f10604b39840a79281185d253
Autor:
Saurabh Kaushik, Gautam V. Soni
Publikováno v:
Biophysical Journal. 122:531a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c53174df3dacbf7fdb437f1e75504b0
https://doi.org/10.1016/j.bpj.2022.11.2815
https://doi.org/10.1016/j.bpj.2022.11.2815
Publikováno v:
Biophysical Journal. 118:379a-380a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::144bf1e0227b7e9c9adf9b6c15082fd4
https://doi.org/10.1016/j.bpj.2019.11.2169
https://doi.org/10.1016/j.bpj.2019.11.2169
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1805
Biological cells sample their surrounding microenvironments using nanoscale force sensors on the cell surfaces. These surface-based force and stress sensors generate physical and chemical responses inside the cell. The inherently well-connected cytos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32178ddd3cd5998071bd279a3ea57544
https://pubmed.ncbi.nlm.nih.gov/29971710
https://pubmed.ncbi.nlm.nih.gov/29971710
Autor:
Don W. Cleveland, Dong Hyun Kim, Bing Ren, Ah Young Lee, Daniele Fachinetti, Kristen Nguyen, Adeline K. Wong, Cees Dekker, Yael Nechemia-Arbely, Ben E. Black, Nikolina Sekulic, Karen H. Miga, Gautam V. Soni
Publikováno v:
The Journal of Cell Biology
The Journal of cell biology, vol 216, iss 3
The Journal of Cell Biology, 216(3)
The Journal of cell biology, vol 216, iss 3
The Journal of Cell Biology, 216(3)
In this study, the authors use new reference models for 23 human centromeres and find that at all cell cycle phases centromeric CENP-A chromatin complexes are octameric nucleosomes with two molecules of CENP-A. This finding refutes previous models th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99694c61d29bcfc442a7c2da8130f4c0
Publikováno v:
Small. 9:679-684
Optical tweezers operated near solid-state membranes show unexplained periodic modulations in the optical trap position. An experimental study of the oscillations is presented, as well as optical simulations based on the finite-difference time-domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c63f24c4374c9f24194c345c093f58
https://doi.org/10.1002/smll.201201875
https://doi.org/10.1002/smll.201201875
Autor:
Gautam V. Soni, Amit Meller
Publikováno v:
Clinical Chemistry. 53:1996-2001
Background: Measurements of the ionic current flowing through nanometer-scale pores (nanopores) have been used to analyze single DNA and RNA molecules, with the ultimate goal of achieving ultrafast DNA sequencing. However, attempts at purely electron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebfbb6e591b755db5677df2f838e65e
https://doi.org/10.1373/clinchem.2007.091231
https://doi.org/10.1373/clinchem.2007.091231