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of 16
pro vyhledávání: '"Gautam K. Sahu"'
Autor:
Gautam K. Sahu
Publikováno v:
AIDS Research and Human Retroviruses. 31:25-35
The current antiretroviral therapy (ART) has suppressed viremia to below the limit of detection of clinical viral load assays; however, it cannot eliminate viremia completely in the body even after prolonged treatment. Plasma HIV-1 loads persist at e
Publikováno v:
Journal of Virology. 84:8348-8352
The clinical significance of persistent residual viremia in patients on prolonged highly active antiretroviral therapy (HAART) is not clear. Moreover, it remains to be demonstrated whether residual viremia consists of viruses capable of spreading inf
Autor:
Melissa M. Smith, Miles W. Cloyd, Scott C. Weaver, Gautam K. Sahu, Simon D. W. Frost, David P. Paar
Publikováno v:
Journal of Medical Virology. 81:9-15
The cellular source(s) and the clinical significance of persistent low-level viremia, below 50 HIV RNA copies per ml of plasma, achieved in many patients with high adherence to highly active antiretroviral therapy (HAART) remain unclear. Also, it is
Publikováno v:
Virology. 355(2):127-137
Studies of mechanisms of HIV-latency and its reactivation in long-lived resting CD4+ T-lymphocytes in patients have been limited due to the very low frequency of these cells ( approximately 1-10 cells per 10(6) CD4+ T-cells). To circumvent this obsta
Autor:
Jingzhi Pan, Joyce Poast, Miles W. Cloyd, Stephen K. Tyring, Samuel Baron, Gautam K. Sahu, Jianmin Chen, Hung Lee
Publikováno v:
Antiviral Research. 70:21-27
Very early detection of HIV infection could help decrease the spread of HIV, improve safety of the blood supply, and permit earlier treatment. Early detection was reported when native gp41 antigen was used to detect antibodies that occurred 2-6 weeks
Publikováno v:
International Immunology. 17:729-736
In HIV-infected patients, increased levels of IL-10, mainly produced by virally infected monocytes, were reported to be associated with impaired cell-mediated immune responses. In this study, we investigated how HIV-1 induces IL-10 production in huma
Autor:
Gautam K. Sahu, Liqiang Wang, David P. Paar, Jianmin Chen, John R. Petersen, Keith M. Ramsey, Miles W. Cloyd, Stephen K. Tyring, Alexander J. Indrikovs, Jenny J.-Y. Chen
Publikováno v:
The Journal of Infectious Diseases. 186:321-331
On the basis of human immunodeficiency virus (HIV) needlestick studies, the time to seroconversion for anti-HIV antibodies is 1-9 months (mean, approximately 2-3 months). However, an earlier marker of an immune response to HIV often occurs-serum anti
Autor:
Edith M. Walker, Gautam K. Sahu, Andrew G. MacLean, Richard P. Junghans, Gail Skowron, Dorothee von Laer, Preston A. Marx, Stephen E. Braun
Background To increase the immunosurveillance in HIV infection, we used retroviral vectors expressing CD4-chimeric antigen receptors (CARs) to genetically modify autologous T cells and redirect CTL toward HIV. The CD4 extracellular domain targets env
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492c4cf386b2d5feb90d690deb77df52
https://europepmc.org/articles/PMC4318253/
https://europepmc.org/articles/PMC4318253/
Autor:
Gautam K. Sahu, Miles W. Cloyd
Publikováno v:
Virology Journal, Vol 8, Iss 1, p 400 (2011)
Virology Journal
Virology Journal
Recently, there is considerable interest in the field of anti-HIV therapy to identify and develop chromatin-modifying histone deacetylase (HDAC) inhibitors that can effectively reactivate latent HIV in patients. The hope is that this would help elimi
Publikováno v:
AIDS. 15:1175-1177