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Evaluation of Apolipoprotein E Fragmentation as a Biomarker for Alzheimer’s Disease

Autor: Gause Jw, Troy T. Rohn, Day Rj, Caraway Ca, Wayne W. Poon

Publikováno v: Journal of Neurology and Neurological Disorders. 3

Recent studies have supported a role for the proteolytic cleavage of apolipoprotein E4 (APOE4) as a potential mechanism for the enhanced dementia risk associated with Alzheimer’s disease. To determine whether APOE4 fragmentation is correlated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7ef20c23d4924b12a2b5e3d2c69d11
https://doi.org/10.15744/2454-4981.3.204

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Akademický článek

Nuclear uptake of an amino-terminal fragment of apolipoprotein E4 promotes cell death and localizes within microglia of the Alzheimer's disease brain.

Autor: Love JE; Department of Biological Sciences, Science/Nursing Building, Room 228, Boise State UniversityBoise 83725, Idaho., Day RJ; Department of Biological Sciences, Science/Nursing Building, Room 228, Boise State UniversityBoise 83725, Idaho., Gause JW; University of Washington, School of MedicineSeattle 98195, WA., Brown RJ; Department of Biological Sciences, Science/Nursing Building, Room 228, Boise State UniversityBoise 83725, Idaho., Pu X; Department of Biological Sciences, Science/Nursing Building, Room 228, Boise State UniversityBoise 83725, Idaho., Theis DI; Department of Biological Sciences, Science/Nursing Building, Room 228, Boise State UniversityBoise 83725, Idaho., Caraway CA; Institute for Memory Impairments and Neurological Disorders UC IrvineIrvine 92697, CA., Poon WW; Institute for Memory Impairments and Neurological Disorders UC IrvineIrvine 92697, CA., Rahman AA; Department of Biological Sciences, Science/Nursing Building, Room 228, Boise State UniversityBoise 83725, Idaho., Morrison BE; Department of Biological Sciences, Science/Nursing Building, Room 228, Boise State UniversityBoise 83725, Idaho., Rohn TT; Department of Biological Sciences, Science/Nursing Building, Room 228, Boise State UniversityBoise 83725, Idaho.

Publikováno v: International journal of physiology, pathophysiology and pharmacology [Int J Physiol Pathophysiol Pharmacol] 2017 Apr 15; Vol. 9 (2), pp. 40-57. Date of Electronic Publication: 2017 Apr 15 (Print Publication: 2017).

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Akademický článek

An amino-terminal fragment of apolipoprotein E4 leads to behavioral deficits, increased PHF-1 immunoreactivity, and mortality in zebrafish.

Autor: McCarthy, Madyson M.¹ (AUTHOR), Hardy, Makenna J.¹ (AUTHOR), Leising, Saylor E.¹ (AUTHOR), LaFollette, Alex M.¹ (AUTHOR), Stewart, Erica S.¹ (AUTHOR), Cogan, Amelia S.¹ (AUTHOR), Sanghal, Tanya¹ (AUTHOR), Matteo, Katie¹ (AUTHOR), Reeck, Jonathon C.¹ (AUTHOR), Oxford, Julia T.¹ (AUTHOR), Rohn, Troy T.¹ (AUTHOR) trohn@boisestate.edu

Publikováno v: PLoS ONE. 12/15/2022, Vol. 17 Issue 12, p1-20. 20p.

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Akademický článek

Functional diversity of apolipoprotein E: from subcellular localization to mitochondrial function.

Autor: Rueter J; Devision of Food Science, Institute of Human Nutrition and Food Science, University of Kiel, Hermann-Rodewald-Strasse 6, 24118, Kiel, Germany., Rimbach G; Devision of Food Science, Institute of Human Nutrition and Food Science, University of Kiel, Hermann-Rodewald-Strasse 6, 24118, Kiel, Germany. rimbach@foodsci.uni-kiel.de., Huebbe P; Devision of Food Science, Institute of Human Nutrition and Food Science, University of Kiel, Hermann-Rodewald-Strasse 6, 24118, Kiel, Germany.

Publikováno v: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2022 Aug 26; Vol. 79 (9), pp. 499. Date of Electronic Publication: 2022 Aug 26.

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