Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Gaurisankar Sa"'
Autor:
Sumon Mukherjee, Sourio Chakraborty, Udit Basak, Subhadip Pati, Apratim Dutta, Saikat Dutta, Dia Roy, Shruti Banerjee, Arpan Ray, Gaurisankar Sa, Tanya Das
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Cancer stem cells (CSCs), being the primary contributors in tumor initiation, metastasis, and relapse, ought to have seminal roles in evasion of immune surveillance. Tumor-promoting CD4+CD25+FOXP3+ T-regulatory cells (Tregs) have been descri
Externí odkaz:
https://doaj.org/article/fd636c507ea044bea5ac9b5617f9980d
Autor:
Sourio Chakraborty, Sumon Mukherjee, Udit Basak, Subhadip Pati, Apratim Dutta, Saikat Dutta, Subhanki Dhar, Tania Sarkar, Aharna Guin, Gaurisankar Sa, Tanya Das
Publikováno v:
Exploration of Immunology, Vol 3, Iss 4, Pp 384-405 (2023)
Cancer stem cells (CSCs) are a small subpopulation of cells that drive the formation and progression of tumors. However, during tumor initiation, how CSCs communicate with neighbouring immune cells to overcome the powerful immune surveillance barrier
Externí odkaz:
https://doaj.org/article/777ed888517245ccac0079cece460259
Autor:
Udit Basak, Tania Sarkar, Sumon Mukherjee, Sourio Chakraborty, Apratim Dutta, Saikat Dutta, Debadatta Nayak, Subhash Kaushik, Tanya Das, Gaurisankar Sa
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cancer progression is primarily caused by interactions between transformed cells and the components of the tumor microenvironment (TME). TAMs (tumor-associated macrophages) make up the majority of the invading immune components, which are further cat
Externí odkaz:
https://doaj.org/article/d41a6ad810574bfaa42b356f92b3cdeb
Publikováno v:
Current Research in Immunology, Vol 2, Iss , Pp 132-141 (2021)
Tumor mass and its microenvironment alter host immune system in various ways to promote tumor growth. One of the modifications is evasion of immune surveillance by augmenting the number of Tregs in tumor vicinity. Elevated levels of Tregs are seen in
Externí odkaz:
https://doaj.org/article/b90e07dfb13c4334a605904ab5c80919
Autor:
Tania Sarkar, Subhanki Dhar, Dwaipayan Chakraborty, Subhadip Pati, Sayantan Bose, Abir K. Panda, Udit Basak, Sourio Chakraborty, Sumon Mukherjee, Aharna Guin, Kuladip Jana, Diptendra K. Sarkar, Gaurisankar Sa
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Infiltrating T-regulatory cells in the tumor microenvironment is a key impediment to immunotherapy and is linked to a poor prognosis. We found that tumor-infiltrating Tregs express a higher expression of the chemokine receptor CCR4 than peripheral Tr
Externí odkaz:
https://doaj.org/article/1a80790418c5408d929dcd25cb2e5055
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The conventional carcinoma treatment generally encompasses the employment of radiotherapy, chemotherapy, surgery or use of cytotoxic drugs. However, recent advances in pharmacological research have divulged the importance of traditional treatments in
Externí odkaz:
https://doaj.org/article/bcb9bf91ee69410ba9cc919d2bd27a6e
Autor:
Silpita Paul, Gaurisankar Sa
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The components of the immune system play a very sincere and crucial role in combating tumors. However, despite their firm efforts of elimination, tumor cells cleverly escape the surveillance process by adopting several immune evasion mechanisms. The
Externí odkaz:
https://doaj.org/article/dfdc858862eb413ba23e0220aa5f626d
Autor:
Sreeparna Chakraborty, Abir K. Panda, Sayantan Bose, Dia Roy, Kirti Kajal, Deblina Guha, Gaurisankar Sa
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract T-regulatory cells are an upsurge in the tumor microenvironment and induce immune-evasion. CD4+ Treg cells are well characterized whereas the role of CD8+ Tregs in cancer has recently started to crease attention. Here, we report an augmentat
Externí odkaz:
https://doaj.org/article/b98775057ebd4917908002096e8aef98
Publikováno v:
Al Ameen Journal of Medical Sciences, Vol 03, Iss 01, Pp 21-37 (2010)
Inhibition of defined molecular steps of tumourigenesis by natural non-toxic compounds may be an efficient means to tackle the population cancer burden. Extensive research has addressed the chemotherapeutic potential of curcumin (diferuloylmethane),
Externí odkaz:
https://doaj.org/article/63311ba966dd486ea05bb4896417f636
Autor:
Barun Mahata, Soumika Biswas, Patricia Rayman, Ali Chahlavi, Jennifer Ko, Ashish Bhattacharjee, Yu-Teh Li, Yuntao Li, Tanya Das, Gaurisankar Sa, Baisakhi Raychaudhuri, Michael A Vogelbaum, Charles Tannenbaum, James H Finke, Kaushik Biswas
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134425 (2015)
Previously we demonstrated that human glioblastoma cell lines induce apoptosis in peripheral blood T cells through partial involvement of secreted gangliosides. Here we show that GBM-derived gangliosides induce apoptosis through involvement of the TN
Externí odkaz:
https://doaj.org/article/e238dd13627245ecb08e4e3ff0d6500b