Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gauri Shadambikar"'
Autor:
Gauri Shadambikar, Sushrut Marathe, Nan Ji, Mashan Almutairi, Suresh Bandari, Feng Zhang, Mahavir Chougule, Michael Repka
Publikováno v:
International Journal of Pharmaceutics: X, Vol 3, Iss , Pp 100074- (2021)
Pulmonary delivery is a promising alternative for the oral treatment of pulmonary aspergillosis. This study aimed to develop continuous and scalable itraconazole PEGylated nano-lipid carriers (ITZ-PEG-NLC) for inhalation delivery. The feasibility of
Externí odkaz:
https://doaj.org/article/976cb0ee04e84701b828b8aaae3ada87
Development of α-Tocopherol Succinate-Based Nanostructured Lipid Carriers for Delivery of Paclitaxel
Autor:
Sushrut Marathe, Gauri Shadambikar, Tabish Mehraj, Suresh P. Sulochana, Narendar Dudhipala, Soumyajit Majumdar
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1034 (2022)
The management of retinoblastoma (RB) involves the use of invasive treatment regimens. Paclitaxel (PTX), an effective antineoplastic compound used in the treatment of a wide range of malignant tumors, poses treatment challenges due to systemic toxici
Externí odkaz:
https://doaj.org/article/0fe4bb683fa045548023c1b1aa5a41d3
Autor:
Gauri Shadambikar, Thomas Kipping, Nicole Di-Gallo, Alessandro-Giuseppe Elia, Anja-Nadine Knüttel, Daniel Treffer, Michael. A Repka
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1019 (2020)
Hot-melt extrusion (HME) is the most preferred and effective method for manufacturing amorphous solid dispersions at production scale, but it consumes large amounts of samples when used for formulation development. Herein, we show a novel approach to
Externí odkaz:
https://doaj.org/article/383fcdb6a6444c969a6cd843df533458
Autor:
Nan Ji, Gauri Shadambikar, Mahavir B. Chougule, Feng Zhang, Suresh Bandari, Mashan Almutairi, Sushrut Marathe, Michael A. Repka
Publikováno v:
International Journal of Pharmaceutics: X
International Journal of Pharmaceutics: X, Vol 3, Iss, Pp 100074-(2021)
International Journal of Pharmaceutics: X, Vol 3, Iss, Pp 100074-(2021)
Pulmonary delivery is a promising alternative for the oral treatment of pulmonary aspergillosis. This study aimed to develop continuous and scalable itraconazole PEGylated nano-lipid carriers (ITZ-PEG-NLC) for inhalation delivery. The feasibility of
Autor:
Soumyajit Majumdar, Suresh Bandari, Gauri Shadambikar, Sushrut Marathe, Michael A. Repka, Akash Patil, Rohit Joshi
Publikováno v:
AAPS PharmSciTech
The objective of this study was to investigate the processability of hot-melt extrusion (HME) to formulate ocular inserts of valacyclovir hydrochloride and evaluate the in vivo bioavailability of the formulation. To optimize the formulation of this d
Autor:
Nicole Di-Gallo, Michael A. Repka, Gauri Shadambikar, Thomas Kipping, Anja-Nadine Knüttel, Daniel Franz Treffer, Alessandro-Giuseppe Elia
Publikováno v:
Pharmaceutics
Volume 12
Issue 11
Pharmaceutics, Vol 12, Iss 1019, p 1019 (2020)
Volume 12
Issue 11
Pharmaceutics, Vol 12, Iss 1019, p 1019 (2020)
Hot-melt extrusion (HME) is the most preferred and effective method for manufacturing amorphous solid dispersions at production scale, but it consumes large amounts of samples when used for formulation development. Herein, we show a novel approach to
Autor:
S. Narasimha Murthy, Karthik Yadav Janga, Michael A. Repka, Nan Ji, Sandeep Sarabu, Tamara King, Pengchong Xu, Sagar Sawant, Gauri Shadambikar
Publikováno v:
AAPS PharmSciTech. 19:48-59
Photodegradation is one of the major pathways of the degradation of drugs. Some therapeutic agents and excipients are highly sensitive to light and undergo significant degradation, challenging the quality and the stability of the final product. The a
Publikováno v:
Journal of Drug Delivery Science and Technology. 60:102002
The aim of the current study was to prepare and compare acyclovir (ACV) floating gastro-retentive formulations synthesized via hot-melt extrusion (HME) techniques using pressurized CO2 and sodium bicarbonate. Physical mixtures of ACV (20%, w/w) and H