Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Gauri H. Malthankar-Phatak"'
Publikováno v:
Journal of Neuropathology and Experimental Neurology
Supplemental Digital Content is available in the text.
The perforant pathway projection from the entorhinal cortex (EC) to the hippocampal dentate gyrus is critically important for long-term memory and develops tau and amyloid pathologies and pr
The perforant pathway projection from the entorhinal cortex (EC) to the hippocampal dentate gyrus is critically important for long-term memory and develops tau and amyloid pathologies and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53c7dcd8960138b3b31f63d59fdee28
https://doi.org/10.1097/nen.0000000000000006
https://doi.org/10.1097/nen.0000000000000006
Publikováno v:
Neurobiology of Aging. 33:1273-1283
Neuropathological features of Alzheimer's disease (AD) are recapitulated in transgenic mice expressing familial AD-causing mutations, but ectopic transgene overexpression makes it difficult to relate these abnormalities to disease pathogenesis. Alter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc141bf28d3925a47be5af4a84990f38
https://doi.org/10.1016/j.neurobiolaging.2010.12.007
https://doi.org/10.1016/j.neurobiolaging.2010.12.007
Autor:
Daniel P. McCloskey, Helen E. Scharfman, Neil J. MacLusky, Sharon Barouk, Juan Gómez, Gauri H. Malthankar-Phatak, Kerry A. Stormes, Tana M. Hintz, Victoria N. Luine
Publikováno v:
European Journal of Neuroscience. 26:2595-2612
In adult female rats, robust hippocampal changes occur when estradiol rises on the morning of proestrus. Whether estradiol mediates these changes, however, remains unknown. To address this issue, we used sequential injections of estradiol to simulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db491c9fddd3355c1bf1a72685790f30
https://doi.org/10.1111/j.1460-9568.2007.05848.x
https://doi.org/10.1111/j.1460-9568.2007.05848.x
Autor:
Jeremy J. Hugus, Gauri H. Malthankar-Phatak, Christopher K. Daniels, Vikas V. Dukhande, James C. K. Lai
Publikováno v:
Neurochemical Research. 31:1349-1357
Manganese (Mn) is neurotoxic: the underlying mechanisms have not been fully elucidated. L: -Buthionine-(S,R)-sulfoximine (BSO) is an irreversible inhibitor of gamma-glutamylcysteine synthetase, an important enzyme in glutathione (GSH) synthesis. To t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628b64426c6c35de9b54af7c340e3ba9
https://doi.org/10.1007/s11064-006-9179-7
https://doi.org/10.1007/s11064-006-9179-7
Autor:
Tih-Shih Lee, Arko Ghosh, Hitten P. Zaveri, James C. K. Lai, Henning Beckström, Tore Eid, Yue Wang, Nihal C. de Lanerolle, Gauri H. Malthankar-Phatak
Publikováno v:
Brain : a journal of neurology. 131(Pt 8)
An excess of extracellular glutamate in the hippocampus has been linked to the generation of recurrent seizures and brain pathology in patients with medically intractable mesial temporal lobe epilepsy (MTLE). However, the mechanism which results in g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05367937cb3f09fdf2d60de331f0a5d
https://pubmed.ncbi.nlm.nih.gov/18669513
https://pubmed.ncbi.nlm.nih.gov/18669513
Autor:
Soon-Sun Hong, Golam M. I. Chowdhury, Ying Xia, Anant B. Patel, Gauri H. Malthankar-Phatak, Kevin L. Behar, James C. K. Lai, Isaac A. Orina
Mechanisms underlying hypoxia-induced neuronal adaptation have not been fully elucidated. In the present study we investigated glucose metabolism and the activities of glycolytic and TCA cycle enzymes in cerebro-cortical neurons exposed to hypoxia (3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcfdf16deb1ee2d44d09d695eb4e7204
https://europepmc.org/articles/PMC2658263/
https://europepmc.org/articles/PMC2658263/
Autor:
Dennis D. Spencer, James C. K. Lai, Jung H. Kim, Tore Eid, Nihal C. de Lanerolle, Susan S. Spencer, Gauri H. Malthankar-Phatak, Kevin L. Behar
Publikováno v:
Epilepsia. 47(8)
Summary: Purpose: Pathophysiologic mechanisms underlying temporal lobe epilepsy (TLE) are still poorly understood. One major hypothesis links alterations in energy metabolism to glutamate excitotoxicity associated with seizures in TLE. The purpose of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01506e1dd69a77c06504d5df68234b85
https://pubmed.ncbi.nlm.nih.gov/16922873
https://pubmed.ncbi.nlm.nih.gov/16922873
Autor:
Neil J. MacLusky, Cynthia L. Harden, Daniel P. McCloskey, Patrice Pearce, Daniel Friedman, Gauri H. Malthankar-Phatak, Helen E. Scharfman
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 94:2671-2671
Epilepsy in women is influenced by endocrine status and antiepileptic drugs (AEDs), but without an animal model, the effects of endocrine variables and AEDs cannot be easily dissociated from the influence of epilepsy itself. Animal models have had li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::039badfa28b3de1d4b2c5c5d581a4748
https://doi.org/10.1210/jcem.94.7.9997
https://doi.org/10.1210/jcem.94.7.9997
Autor:
Kathryn Sandberg, Daniel P. McCloskey, Tana M. Hintz, Darren M. Roesch, Helen E. Scharfman, Gauri H. Malthankar-Phatak, Neil J. MacLusky
Publikováno v:
American Journal of Obstetrics and Gynecology. 197:S125
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31fed70ff245aba48dd0934974c81f63
https://doi.org/10.1016/j.ajog.2007.10.436
https://doi.org/10.1016/j.ajog.2007.10.436
Autor:
Tore Eid, Arko Ghosh, Yue Wang, Henning Beckström, Hitten P. Zaveri, Tih-Shih W. Lee, James C. K. Lai, Gauri H. Malthankar-Phatak, Nihal C. de Lanerolle
Publikováno v:
Brain: A Journal of Neurology; Aug2008, Vol. 131 Issue 8, p2061-2061, 1p