Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gauravi Deshpande"'
Autor:
Dionysios C. Watson, Defne Bayik, Simon Storevik, Shannon Sherwin Moreino, Samuel A. Sprowls, Jianhua Han, Mina Thue Augustsson, Adam Lauko, Palavalasa Sravya, Gro Vatne Røsland, Katie Troike, Karl Johan Tronstad, Sabrina Wang, Katharina Sarnow, Kristen Kay, Taral R. Lunavat, Daniel J. Silver, Sahil Dayal, Justin Vareecal Joseph, Erin Mulkearns-Hubert, Lars Andreas Rømo Ystaas, Gauravi Deshpande, Joris Guyon, Yadi Zhou, Capucine R. Magaut, Juliana Seder, Laura Neises, Sarah E. Williford, Johannes Meiser, Andrew J. Scott, Peter Sajjakulnukit, Jason A. Mears, Rolf Bjerkvig, Abhishek Chakraborty, Thomas Daubon, Feixiong Cheng, Costas A. Lyssiotis, Daniel R. Wahl, Anita B. Hjelmeland, Jubayer A. Hossain, Hrvoje Miletic, Justin D. Lathia
Publikováno v:
Nature Cancer. 4:648-664
The transfer of intact mitochondria between heterogeneous cell types has been confirmed in various settings, including cancer. However, the functional implications of mitochondria transfer on tumor biology are poorly understood. Here we show that mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e2cd76169f757aefbec27866da906b8
https://doi.org/10.1038/s43018-023-00556-5
https://doi.org/10.1038/s43018-023-00556-5
Autor:
Fan Lu, Jianmin Liu, Sujay Subbayya Ithychanda, Marcin Apostol, Mitali Das, Gauravi Deshpande, Edward F. Plow, Jun Qin
Publikováno v:
Blood.
The communication of talin-activated integrin aIIbb3 with cytoskeleton (integrin outside-in signaling) is essential for platelet aggregation, wound healing, and hemostasis. Filamin, a large actin cross-linker and integrin binding partner critical for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8261969276b292615127fee6e39a84ae
https://doi.org/10.1182/blood.2022018333
https://doi.org/10.1182/blood.2022018333
Autor:
Sumeda Nandadasa, Daniel Martin, Gauravi Deshpande, Karyn L. Robert, M. Sharon Stack, Yoshifumi Itoh, Suneel S. Apte
SummaryThe secreted metalloproteases ADAMTS9 and ADAMTS20 are implicated in extracellular matrix (ECM) proteolysis and primary cilium biogenesis. Here, we show that clonal gene-edited RPE-1 cells in whichADAMTS9was inactivated, and which constitutive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3aac8acfc281635a147f5bb7a1b455
https://doi.org/10.1101/2022.10.17.512574
https://doi.org/10.1101/2022.10.17.512574
Autor:
Dionysios C. Watson, Defne Bayik, Simon Storevik, Shannon S. Moreino, Samuel S. Sprowls, Gauravi Deshpande, Palavalasa Sravya, Costas A. Lyssiotis, Daniel R. Wahl, Hrvoje Miletic, Justin D. Lathia
Publikováno v:
Cancer Research. 83:331-331
Mitochondrial transfer in the central nervous system occurs from astrocytes to neurons in stroke. Mitochondrial exchange has also been reported among tumor cells in glioblastoma (GBM), the most common primary brain tumor. However, the role of mitocho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc3ff4e0a850e648ab827151d20c019e
https://doi.org/10.1158/1538-7445.am2023-331
https://doi.org/10.1158/1538-7445.am2023-331
Autor:
Dionysios Watson, Defne Bayik, Adam Lauko, Samuel Sprowls, Gauravi Deshpande, Sarah Wilifford, Katie Troike, Daniel Silver, Sabrina Wang, Juliana Seder, Kristen Kay, Anita Hjelmeland, Justin Lathia
Publikováno v:
Neuro-Oncology. 24:vii286-vii287
Mitochondrial transfer occurs both in stroke (central nervous system) and inflammatory pain (peripheral nerves). However, its role in glioblastoma (GBM) remains poorly understood. We hypothesized that mitochondrial transfer from non-malignant to GBM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c48fd900218213d93f231afbb563a76
https://doi.org/10.1093/neuonc/noac209.1112
https://doi.org/10.1093/neuonc/noac209.1112
Autor:
Dionysios C. Watson, Juliana Seder, Gauravi Deshpande, Yadi Zhou, Sarah E Williford, Feixiong Cheng, Anita B. Hjelmeland, Adam Lauko, Justin D. Lathia, Defne Bayik, Jason A. Mears
Glioblastoma (GBM), the most common primary brain cancer in adults1, is characterized by numerous cell-intrinsic/extrinsic interactions that drive tumorigenesis. In addition to cell-surface and secreted protein/extracellular vesicle interactions2,3,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17bb6795769eb451c0bcc74809f47a4d
https://doi.org/10.21203/rs.3.rs-923533/v1
https://doi.org/10.21203/rs.3.rs-923533/v1
Autor:
Sarah E Williford, Justin D. Lathia, Defne Bayik, Yadi Zhou, Adam Lauko, Juliana Seder, Dionysios C. Watson, Jason A. Mears, Feixiong Cheng, Anita B. Hjelmeland, Gauravi Deshpande
While dynamic microenvironmental interactions drive tumor growth and therapeutic resistance, the underlying direct cell-cell communication mechanisms remain poorly understood. We identified horizontal mitochondrial transfer as a mechanism that enhanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::797623becf6bf64ed58d8d0b7fd701f8
https://doi.org/10.1101/2021.09.01.458565
https://doi.org/10.1101/2021.09.01.458565