Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gaurav V. Sarode"'
Autor:
Gaurav V. Sarode, Kari Neier, Noreene M. Shibata, Yuanjun Shen, Dmitry A. Goncharov, Elena A. Goncharova, Tagreed A. Mazi, Nikhil Joshi, Matthew L. Settles, Janine M. LaSalle, Valentina Medici
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1457-1477 (2021)
Background & Aims: The pathogenesis of Wilson disease (WD) involves hepatic and brain copper accumulation resulting from pathogenic variants affecting the ATP7B gene and downstream epigenetic and metabolic mechanisms. Prior methylome investigations i
Externí odkaz:
https://doaj.org/article/c5ffc517af1647e8b7ee2257791baec3
Autor:
Gaurav V. Sarode, Tagreed A. Mazi, Kari Neier, Noreene M. Shibata, Guillaume Jospin, Nathaniel H.O. Harder, Marie C. Heffern, Ashok K. Sharma, Shyam K. More, Maneesh Dave, Shannon M. Schroeder, Li Wang, Janine M. LaSalle, Svetlana Lutsenko, Valentina Medici
Publikováno v:
bioRxiv
Background and aimsMajor clinical manifestations of Wilson disease (WD) are related to copper accumulation in the liver and the brain, and little is known about other tissues involvement in metabolic changes in WD.In vitrostudies suggested that the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81091c2d37227a2143f15658b3dbf7d7
https://europepmc.org/articles/PMC9882126/
https://europepmc.org/articles/PMC9882126/
Autor:
Gaurav V. Sarode, Janine M. LaSalle, Tagreed A. Mazi, Gyu-Young Song, Cecilia R Giulivi, Tomasz Litwin, Anna Członkowska, Charles E. Mordaunt, Eleonora Napoli, Dorothy A. Kieffer, Andre Oliveira Guimarães, Noreene M. Shibata, Valentina Medici
Publikováno v:
Liver Int
BACKGROUND & AIMS: Wilson disease is caused by mutations in the copper transporter ATP7B, with its main pathology attributed to copper-mediated oxidative damage. The limited therapeutic effect of copper chelators and the early occurrence of mitochond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d7920840357f487cc5d6b37d02dd5b
https://doi.org/10.1111/liv.14646
https://doi.org/10.1111/liv.14646
Autor:
Nikhil Joshi, Tagreed A. Mazi, Valentina Medici, Gaurav V. Sarode, Dmitry A. Goncharov, Noreene M. Shibata, Yuanjun Shen, Matthew L. Settles, Janine M. LaSalle, Elena A. Goncharova, Kari Neier
Publikováno v:
Cellular and molecular gastroenterology and hepatology, vol 12, iss 4
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1457-1477 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1457-1477 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The pathogenesis of Wilson disease (WD) involves hepatic and brain copper accumulation resulting from pathogenic variants affecting the ATP7B gene and downstream epigenetic and metabolic mechanisms. Prior methylome investigations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2024060a3a5df6fc62b754ef0b849667
https://escholarship.org/uc/item/1p2359jk
https://escholarship.org/uc/item/1p2359jk
Autor:
Anna Członkowska, Kyoungmi Kim, Noreene M. Shibata, Tomas Litwin, Gaurav V. Sarode, Dorothy A. Kieffer, Valentina Medici
Publikováno v:
Metabolomics. 16
In the originally published version of this article, there was an error. The metabolomics platform used for the analysis is GC-TOF-MS, Gas Chromatography Time-of-Flight Mass Spectrometry and not Hydrophilic Interaction Liquid Chromatography-Quadrupol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a4a6414b32a0ab3cffcb45ef33f9922
https://doi.org/10.1007/s11306-019-1623-1
https://doi.org/10.1007/s11306-019-1623-1
Autor:
Gaurav V. Sarode, Tagreed A. Mazi, Noreene M. Shibata, Valentina Medici, Tomasz Litwin, Anna Członkowska, Kyoungmi Kim
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 23
International journal of molecular sciences, vol 20, iss 23
Volume 20
Issue 23
International journal of molecular sciences, vol 20, iss 23
Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis. Dysregulated methionine cycle is reported in animal models of WD, though not verified in humans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0bda881ae6f6016b8b8e59afdaeaa25
http://europepmc.org/articles/PMC6928853
http://europepmc.org/articles/PMC6928853
Autor:
Noreene M. Shibata, Anna Członkowska, Kyoungmi Kim, Valentina Medici, Tomas Litwin, Dorothy A. Kieffer, Gaurav V. Sarode
Publikováno v:
Metabolomics : Official journal of the Metabolomic Society, vol 15, iss 3
INTRODUCTION: Wilson disease (WD) is characterized by excessive intracellular copper accumulation in liver and brain due to defective copper biliary excretion. With highly varied phenotypes and a lack of biomarkers for the different clinical manifest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa84eeff0d54fa4a777500c94ceb1c5
https://escholarship.org/uc/item/7pg305sn
https://escholarship.org/uc/item/7pg305sn
Autor:
Christopher L. Bowlus, Gaurav V. Sarode, Tomasz Litwin, Anna Członkowska, Charles E. Mordaunt, Valentina Medici, Karl Heinz Weiss, Janine M. LaSalle, Noreene Shibata
Publikováno v:
Journal of Hepatology. 70:e587
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ef6ccd4a662609c80ba790bd9cc8eed
https://doi.org/10.1016/s0618-8278(19)31175-2
https://doi.org/10.1016/s0618-8278(19)31175-2