Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Gaurav S, Gulsin"'
Autor:
Noor Sharrack, Kristopher D. Knott, Gaurav S. Gulsin, Tushar Kotecha, Louise A. E. Brown, Jian L. Yeo, Aldostefano Porcari, Robert D. Adam, Sharmaine Thirunavukarasu, Amrit Chowdhary, Eylem Levelt, James C. Moon, Gerry P. McCann, Marianna Fontana, Peter Kellman, Theresa Munyombwe, Chris P. Gale, David L. Buckley, John P. Greenwood, Peter P. Swoboda, Sven Plein
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Metformin is an antihyperglycemic used to treat type 2 diabetes mellitus (T2DM). Patients with T2DM are at increased risk of cardiovascular disease. We explored the association between metformin use and cardiovascular magnetic resonance (CMR
Externí odkaz:
https://doaj.org/article/f658e09e703244519798bd09cc870527
Autor:
Saadia Aslam, Abhishek Dattani, Aseel Alfuhied, Gaurav S. Gulsin, Jayanth R. Arnold, Christopher D. Steadman, Michael Jerosch-Herold, Hui Xue, Peter Kellman, Gerry P. McCann, Anvesha Singh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Aortic valve replacement (AVR) leads to reverse cardiac remodeling in patients with aortic stenosis (AS). The aim of this secondary pooled analysis was to assess the degree and determinants of changes in myocardial perfusion post AVR, and it
Externí odkaz:
https://doaj.org/article/d4d91e400e664162ab2068acd0176686
Autor:
Joanna M. Bilak, Gaurav S. Gulsin, Vasiliki Bountziouka, Kelly S. Parke, Emma Redman, Joseph Henson, Lei Zhao, Phillipe Costet, Mary Ellen Cvijic, Juan Maya, Ching-Pin Chang, Melanie J. Davies, Thomas Yates, Gerry P. McCann, Emer M. Brady
Publikováno v:
Hearts, Vol 5, Iss 1, Pp 165-181 (2024)
Background: This study assesses the temporal responses of cardiovascular function, fibro-inflammation, and glucometabolic profiles in asymptomatic adults with type 2 diabetes, following a low-energy meal replacement plan (MRP) or exercise training. M
Externí odkaz:
https://doaj.org/article/d1bb9c4412824338a137d2822d795b4f
Autor:
Abhishek Dattani, Emer M. Brady, Prathap Kanagala, Svetlana Stoma, Kelly S. Parke, Anna-Marie Marsh, Anvesha Singh, Jayanth R. Arnold, Alastair J. Moss, Lei Zhao, Mary Ellen Cvijic, Matthew Fronheiser, Shuyan Du, Philippe Costet, Peter Schafer, Leon Carayannopoulos, Ching-Pin Chang, David Gordon, Francisco Ramirez-Valle, Michael Jerosch-Herold, Christopher P. Nelson, Iain B. Squire, Leong L. Ng, Gaurav S. Gulsin, Gerry P. McCann
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) frequently co-exist. There is a limited understanding on whether this coexistence is associated with distinct alterations in myocardial remodellin
Externí odkaz:
https://doaj.org/article/4215841e5eec4d4b893e3592affdca59
Autor:
Emer M. Brady, Thong H. Cao, Alastair J. Moss, Lavanya Athithan, Sarah L. Ayton, Emma Redman, Stavroula Argyridou, Matthew P. M. Graham-Brown, Colleen B. Maxwell, Donald J. L. Jones, Leong Ng, Thomas Yates, Melanie J Davies, Gerry P. McCann, Gaurav S. Gulsin
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Heart failure with preserved ejection fraction (HFpEF) is a heterogenous multi-system syndrome with limited efficacious treatment options. The prevalence of Type 2 diabetes (T2D) continues to rise and predisposes patients to HFpEF
Externí odkaz:
https://doaj.org/article/f14530763f914e7b9f6525e1d8bcef3b
Autor:
Abhishek Dattani, Jian L. Yeo, Emer M. Brady, Alice Cowley, Anna-Marie Marsh, Manjit Sian, Joanna M. Bilak, Matthew P.M. Graham-Brown, Anvesha Singh, Jayanth R. Arnold, David Adlam, Thomas Yates, Gerry P. McCann, Gaurav S. Gulsin
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss 2, Pp 101120- (2024)
ABSTRACT: Background: Type 2 diabetes (T2D) leads to cardiovascular remodeling, and heart failure has emerged as a major complication of T2D. There is a limited understanding of the impact of T2D on the right heart. This study aimed to assess subclin
Externí odkaz:
https://doaj.org/article/dd41c3e7edb84c94b5530b410af2a907
Autor:
Abhishek Dattani, Benjamin A. Marrow, Gaurav S. Gulsin, Jian L. Yeo, Amitha Puranik, Emer M. Brady, David Adlam, Anvesha Singh, Mohammedimran M. Ansari, Jayanth R. Arnold, Hui Xue, Peter Kellman, James S. Ware, Gerry P. McCann
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss 2, Pp 101108- (2024)
ABSTRACT: Background: Aerobic exercise capacity is an independent predictor of mortality in dilated cardiomyopathy (DCM), but the central mechanisms contributing to exercise intolerance in DCM are unknown. The aim of this study was to characterize co
Externí odkaz:
https://doaj.org/article/165ca752aab74d4b969c7f60f221768a
Autor:
Kelly S. Parke, Emer M. Brady, Aseel Alfuhied, Rishabh S. Motiwale, Cameron S. Razieh, Anvesha Singh, Jayanth R. Arnold, Matthew P.M. Graham-Brown, Joanna M. Bilak, Sarah L. Ayton, Abhishek Dattani, Jian L. Yeo, Gerry P. McCann, Gaurav S. Gulsin
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss 1, Pp 100001- (2024)
Background: Echocardiographic studies indicate South Asian people have smaller ventricular volumes, lower mass and more concentric remodelling than White European people, but there are no data using cardiac MRI (CMR). We aimed to compare CMR quantifi
Externí odkaz:
https://doaj.org/article/d63f01a5017c4c4982d0b67c14058113
Autor:
Abhishek Dattani, Saadia Aslam, Gaurav S. Gulsin, Aseel Alfuhied, Trisha Singh, Shruti S. Joshi, Lucy E. Kershaw, David E. Newby, Gerry P. McCann, Anvesha Singh
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss 2, Pp 101074- (2024)
Background: Dysregulated myocardial calcium handling has been demonstrated in ischemic, non-ischemic and diabetic cardiomyopathy. Manganese-enhanced MRI (MEMRI) provides a unique method to quantify in-vivo myocardial calcium uptake but no studies hav
Externí odkaz:
https://doaj.org/article/11f43cb0aed2418aa9545b01f4e3dc4e
Autor:
David Gordon, Kai Hogrefe, Thomas Yates, Anvesha Singh, Leong L Ng, Gerry P McCann, Lei Zhao, Emer M Brady, Hui Xue, John Greenwood, Peter Kellman, Gaurav S Gulsin, Christopher D Steadman, Dana Dawson, Michael Jerosch-Herold, Aseel Alfuhied, Saadia Aslam, Damian Kelly, J Ranjit Arnold, Jian L Yeo, Abhishek Dattani, Marko Banovic, Philippe Costet, Mary Ellen Cvijic, Christina Ebert, Laura Liu, Kushan Gunawardhana, Ching-Pin Chang
Publikováno v:
Open Heart, Vol 10, Iss 2 (2023)
Objective To characterise cardiac remodelling, exercise capacity and fibroinflammatory biomarkers in patients with aortic stenosis (AS) with and without diabetes, and assess the impact of diabetes on outcomes.Methods Patients with moderate or severe
Externí odkaz:
https://doaj.org/article/386c4fdb14d840bdac0f54bac8a4553b