Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Gaurav Kwatra"'
Autor:
Portia C. Mutevedzi, Vusie Lokotfwako, Gaurav Kwatra, Gugu Maphalala, Vicky Baillie, Lindiwe Dlamini, Senzokuhle Dlamini, Fortune Mhlanga, Tenelisiwe Dlamini, Nhlanhla Nhlabatsi, Marta C. Nunes, Simon Zwane, Shabir A. Madhi
Publikováno v:
COVID, Vol 4, Iss 3, Pp 317-333 (2024)
Background: Seroepidemiology studies are useful for quantifying the magnitude of past infections and estimating the extent of population-based immunity to inform risk mitigation strategies for the future. We report on the only national population-bas
Externí odkaz:
https://doaj.org/article/a0c4564477e4492d95b2bbb2a08d40e2
Autor:
Dennis Hoving, Alexandre H. C. Marques, Wesley Huisman, Beckley A. Nosoh, Alicia C. de Kroon, Oscar R. J. van Hengel, Bing-Ru Wu, Rosanne A. M. Steenbergen, Pauline M. van Helden, Britta C. Urban, Nisha Dhar, Daniela M. Ferreira, Gaurav Kwatra, Cornelis H. Hokke, Simon P. Jochems
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Bacterial capsular polysaccharides are important vaccine immunogens. However, the study of polysaccharide-specific immune responses has been hindered by technical restrictions. Here, we developed and validated a high-throughput method to ana
Externí odkaz:
https://doaj.org/article/9cc08f4b95f4401d8d74a185a887fc67
Autor:
Nisha Dhar, Ebrahim Mohamed, Frank Kirstein, Matthew Williams, Shantal Dorasamy, Petrus van Zyl, Madelyn Johnstone Robertson, Taigh Anderson, Lois M. Harden, Kimberly Jardine, Balaji Veeraraghavan, Seanette Wilson, Patrick Tippoo, Shabir A. Madhi, Gaurav Kwatra
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107380- (2023)
Summary: Immunization of pregnant women with Group B Streptococcus (GBS) capsular polysaccharide (CPS) conjugate vaccine (CV) could protect young infants against invasive GBS disease. We evaluated the immunogenicity of investigational five GBS monova
Externí odkaz:
https://doaj.org/article/4296eddc5fd247e4b0292c229f841e00
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
Invasive group B streptococcal (GBS) disease is the commonest perinatally-acquired bacterial infection in newborns; the burden is higher in African countries where intrapartum antibiotic prophylaxis strategies are not feasible. In sub-Saharan Africa,
Externí odkaz:
https://doaj.org/article/7144c297e63548f48cb1b4e74b154e73
Autor:
Kirsty Le Doare, Michelle A. Gaylord, Annaliesa S. Anderson, Nick Andrews, Carol J. Baker, Shanna Bolcen, Arif Felek, Peter C. Giardina, Christopher D. Grube, Tom Hall, Bassam Hallis, Alane Izu, Shabir A. Madhi, Pete Maniatis, Mary Matheson, Fatme Mawas, Andrew McKeen, Julia Rhodes, Bailey Alston, Palak Patel, Stephanie Schrag, Raphael Simon, Charles Y. Tan, Stephen Taylor, Gaurav Kwatra, Andrew Gorringe
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTMeasurement of IgG antibodies against group B streptococcus (GBS) capsular polysaccharide (CPS) by use of a standardized and internationally accepted multiplex immunoassay is important for the evaluation of candidate maternal GBS vaccines in
Externí odkaz:
https://doaj.org/article/46ead07e882e4125ad972a32edff7d7d
Autor:
Stephanie Leung, Clare F. Collett, Lauren Allen, Suzanna Lim, Pete Maniatis, Shanna J. Bolcen, Bailey Alston, Palak Y. Patel, Gaurav Kwatra, Tom Hall, Stephen Thomas, Stephen Taylor, Kirsty Le Doare, Andrew Gorringe
Publikováno v:
Vaccines, Vol 11, Iss 11, p 1703 (2023)
The placental transfer of antibodies that mediate bacterial clearance via phagocytes is likely important for protection against invasive group B Streptococcus (GBS) disease. A robust functional assay is essential to determine the immune correlates of
Externí odkaz:
https://doaj.org/article/250ee52f1a2c4f8eb115f75001b591e6
Autor:
Cathrine Scheepers, Josie Everatt, Daniel G. Amoako, Houriiyah Tegally, Constantinos Kurt Wibmer, Anele Mnguni, Arshad Ismail, Boitshoko Mahlangu, Bronwen E. Lambson, Darren P. Martin, Eduan Wilkinson, James Emmanuel San, Jennifer Giandhari, Nelia Manamela, Noxolo Ntuli, Prudence Kgagudi, Sandile Cele, Simone I. Richardson, Sureshnee Pillay, Thabo Mohale, Upasana Ramphal, Yeshnee Naidoo, Zamantungwa T. Khumalo, Gaurav Kwatra, Glenda Gray, Linda-Gail Bekker, Shabir A. Madhi, Vicky Baillie, Wesley C. Van Voorhis, Florette K. Treurnicht, Marietjie Venter, Koleka Mlisana, Nicole Wolter, Alex Sigal, Carolyn Williamson, Nei-yuan Hsiao, Nokukhanya Msomi, Tongai Maponga, Wolfgang Preiser, Zinhle Makatini, Richard Lessells, Penny L. Moore, Tulio de Oliveira, Anne von Gottberg, Jinal N. Bhiman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
The SARS-CoV-2 PANGO lineage C.1.2 has been under monitoring by global health authorities as it has spread worldwide. Here, Bhiman and colleagues characterise the emergence of the lineage, and its neutralisation sensitivity using data from vaccinees
Externí odkaz:
https://doaj.org/article/e365317a28774fd29c4b6a0f6a77a17a
Autor:
Marah G. Chibwana, Thandeka Moyo-Gwete, Gaurav Kwatra, Jonathan Mandolo, Tandile Hermanaus, Thopisang Motlou, Nonkululeko Mzindle, Frances Ayres, Mphatso Chaponda, Godwin Tembo, Percy Mwenechanya, Ndaona Mitole, Chisomo Jassi, Raphael Kamng’ona, Louise Afran, David Mzinza, Henry C. Mwandumba, Stephen B. Gordon, Khuzwayo Jere, Shabir Madhi, Penny L. Moore, Robert S. Heyderman, Kondwani C. Jambo
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background Binding and neutralising anti-Spike antibodies play a key role in immune defence against SARS-CoV-2 infection. Since it is known that antibodies wane with time and new immune-evasive variants are emerging, we aimed to assess the d
Externí odkaz:
https://doaj.org/article/b08b88ed1702406caaffe4634de9775e
Publikováno v:
BMC Medical Research Methodology, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Background Group B Streptococcus (GBS) infections are a major cause of invasive disease (IGbsD) in young infants and cause miscarriage and stillbirths. Immunization of pregnant women against GBS in addition to intrapartum antibiotic prophyla
Externí odkaz:
https://doaj.org/article/c8cc3d1c7a6841aa940ca764b5e4f6a3
Autor:
Jamisha D. Francis, Miriam A. Guevara, Jacky Lu, Shabir A. Madhi, Gaurav Kwatra, David M. Aronoff, Shannon D. Manning, Jennifer A. Gaddy
Publikováno v:
BMC Microbiology, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Streptococcus agalactiae or Group B Streptococcus (GBS) is an encapsulated gram-positive bacterial pathobiont that commonly colonizes the lower gastrointestinal tract and reproductive tract of human hosts. This bacterium can infec
Externí odkaz:
https://doaj.org/article/025e3e037b5f4953a372a109f7f05c55