Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Gaurav A. Mehta"'
Autor:
Gaurav A. Mehta, Steven P. Angus, Christen A. Khella, Kevin Tong, Pooja Khanna, Shelley A. H. Dixon, Michael P. Verzi, Gary L. Johnson, Michael L. Gatza
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-15 (2021)
Abstract Dysregulation of PI3K/Akt signaling is a dominant feature in basal-like or triple-negative breast cancers (TNBC). However, the mechanisms regulating this pathway are largely unknown in this subset of aggressive tumors. Here we demonstrate th
Externí odkaz:
https://doaj.org/article/b80593287fd5486295801c1046cbf0bb
Publikováno v:
EBioMedicine, Vol 50, Iss , Pp 191-202 (2019)
Background: Despite toxic side effects and limited durable response, the current standard-of-care treatment for high grade serous ovarian cancer (HGSOC) remains platinum/taxane-based chemotherapy. Given that the overall prognosis has not improved dra
Externí odkaz:
https://doaj.org/article/34b7b7bc756c462188acf3b5fb3b6a22
Autor:
Alexandra Thomas, Eric D. Routh, Ashok Pullikuth, Guangxu Jin, Jing Su, Jeff W. Chou, Katherine A. Hoadley, Cristin Print, Nick Knowlton, Michael A. Black, Sandra Demaria, Ena Wang, Davide Bedognetti, Wendell D. Jones, Gaurav A. Mehta, Michael L. Gatza, Charles M. Perou, David B. Page, Pierre Triozzi, Lance D. Miller
Publikováno v:
OncoImmunology, Vol 7, Iss 10 (2018)
Mounting evidence supports a role for the immune system in breast cancer outcomes. The ability to distinguish highly immunogenic tumors susceptible to anti-tumor immunity from weakly immunogenic or inherently immune-resistant tumors would guide devel
Externí odkaz:
https://doaj.org/article/5c1e86749b8f4e34bf035b1f784d1f98
Autor:
Namrata Shastri, Shulagna Sharma, Anushikha Thakur, H. Pai, Arnab Bera, Ramakrishnan Melarkode, Shankara Annegowda, Sneha Trivedi, Deepa Mohan, Abhilashi Sahu, Pradip Nair, Sheija Rohil, Pradeep Kabadi, Ranitendranath Tagore, Rajesh Ullanat, Malini Subbarao, Roshni Thomas, Gaurav R Mehta, Parag Goyal, Roopa Venkatachala, Bhavesh Vats, Chethan Gejjalagere Honnappa, Yatika Gokhale, Umamaheshwara Rao K, Laxmi Adhikari
Publikováno v:
Expert Opinion on Biological Therapy. 22:271-298
BACKGROUND Bevacizumab (BEV) is a recombinant humanized monoclonal immunoglobulin G1 antibody that binds to vascular endothelial growth factor (VEGF)-A and acts as an antiangiogenic agent. It is approved for treatment of many cancer indications, incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9635e2d2c904b03d145fa00a515d24fa
https://doi.org/10.1080/14712598.2021.1973426
https://doi.org/10.1080/14712598.2021.1973426
Autor:
Arnab Bera, Jeffrey Smith, Bhavesh Vats, Daniel J. Ranayhossaini, Rajesh Ullanat, H. Pai, Gaurav R Mehta, Pradeep Kabadi, Ankita Singh, Praveen Reddy Moole, Abhilashi Sahu, Ramakrishnan Melarkode, Maninder Kaur, Malini Subbarao, Parag Goyal, Laxmi Adhikary, Jyoti Iyer, Shankara Gouda, Arindam Saha, Ashwani Marwah
Publikováno v:
Future Medicinal Chemistry. 13:1531-1557
Aims: Preclinical comparative similarity studies of trastuzumab-dkst, a Herceptin® biosimilar, are reported. Materials & methods: Primary sequence and higher order structure and pharmacological mechanisms of action were compared using multiple techn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8564398914d00ad5e5deb9eb84a59c3f
https://doi.org/10.4155/fmc-2021-0113
https://doi.org/10.4155/fmc-2021-0113
Autor:
Gary K. Owens, Vanessa A. Hajzus, Gilbert R. Upchurch, Carl A. Whatling, Gaurav S. Mehta, Gorav Ailawadi, Gang Su, Akshaya K. Meher, Castigliano M. Bhamidipati, Morgan Salmon
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34:2669-2678
Objective— The impact of leukotriene production by the 5-lipoxygenase (5-LO) pathway in the pathophysiology of abdominal aortic aneurysms (AAAs) has been debated. Moreover, a clear mechanism through which 5-LO influences AAA remains unclear. Approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5132ff3ea94273e2147874a13be409
https://doi.org/10.1161/atvbaha.114.304016
https://doi.org/10.1161/atvbaha.114.304016
Publikováno v:
Journal of Cardiac Surgery. 31:203-205
Transcatheter valve placement complicated by left ventricular embolization is often treated with sternotomy, valve removal through the aorta, and conventional aortic valve replacement. We report three cases of ventricular embolization of aortic valve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a146c4e19bd7cd8b9a378a7bd2b54b6
https://doi.org/10.1111/jocs.12701
https://doi.org/10.1111/jocs.12701
Autor:
Guanyi Lu, Castigliano M. Bhamidipati, Christopher W. Moehle, Gilbert R. Upchurch, Gaurav S. Mehta, Irving L. Kron, Gorav Ailawadi, Adriana Laser, Carlos Barbery, Paul D. DiMusto
Publikováno v:
Surgery. 152:238-246
Background Our aim was to establish a novel model of abdominal aortic aneurysms (AAA) in mice using application of peri-adventitial elastase. Methods C57BL/6J male mice underwent infrarenal peri-adventitial application of either (1) sodium chloride (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcad61faf3ac9fd5135af0fbf5e89ae
https://doi.org/10.1016/j.surg.2012.02.010
https://doi.org/10.1016/j.surg.2012.02.010
Autor:
Damien J. LaPar, John A. Kern, Gorav Ailawadi, Castigliano M. Bhamidipati, Gaurav S. Mehta, Irving L. Kron, Gilbert R. Upchurch
Publikováno v:
Surgery. 152:5-11
Background We hypothesized that the incidence of previous percutaneous coronary intervention (PCI) is increasing and that prior PCI influences patient morbidity and mortality after coronary artery bypass grafting (CABG). Methods A total of 34,316 pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c2c3a944539e86c4bc8edc9d0db185
https://doi.org/10.1016/j.surg.2012.02.013
https://doi.org/10.1016/j.surg.2012.02.013
Publikováno v:
Phycological Research. 59:244-249
SUMMARY Galactans containing methylated galactan moieties were extracted from Indian agarophytes, namely, Gracilaria millardetii and Gracilaria textorii growing naturally along the west coast of India. The galactans were treated with α-amylase to re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15061684149a15844a615b1c04d3fe2f
https://doi.org/10.1111/j.1440-1835.2011.00622.x
https://doi.org/10.1111/j.1440-1835.2011.00622.x