Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gaurang P Bhide"'
Autor:
Gaurang P Bhide, Natalie E Bohrer, Danying Song, Jeanne Cabel, Marc R Lake, John E Harlan, Laura J Miesbauer
Publikováno v:
Glycobiology.
Monoclonal antibodies comprise a major class of biologic therapeutics and are also extensively studied in immunology. Given the importance of glycans on antibodies, fluorescent labeling of enzymatically released glycans and their LC/MS analysis is ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e7f25022f8c7c4340c4b1f7e4f19231
https://doi.org/10.1093/glycob/cwad020
https://doi.org/10.1093/glycob/cwad020
Autor:
Helena L. Palka-Hamblin, Karen J. Colley, Hao Jui Hsu, Michael Cheong, Seungpyo Hong, Gaurang P. Bhide, Ja Hye Myung
Publikováno v:
Analytical Chemistry. 90:3670-3675
Enumeration of circulating tumor cells (CTCs) of small-cell lung cancer (SCLC) patients has been shown to predict the disease progress and long-term survival. Most CTC detection methods rely on epithelial surface markers, such as epithelial cell adhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2cb29659be28d0c5214d543dafc135
https://doi.org/10.1021/acs.analchem.8b00427
https://doi.org/10.1021/acs.analchem.8b00427
Publikováno v:
Journal of Biological Chemistry. 293:701-716
Polysialic acid (polySia) is a large glycan polymer that is added to some glycoproteins by two polysialyltransferases (polySTs), ST8Sia-II and ST8Sia-IV. As polySia modulates cell adhesion and signaling, immune cell function, and tumor metastasis, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616561f3d7a32103a974715fa226eaee
https://doi.org/10.1074/jbc.ra117.000401
https://doi.org/10.1074/jbc.ra117.000401
Autor:
Karen J. Colley, Gaurang P. Bhide
Publikováno v:
Histochemistry and Cell Biology
Sialylated N-glycans play essential roles in the immune system, pathogen recognition and cancer. This review approaches the sialylation of N-glycans from three perspectives. The first section focuses on the sialyltransferases that add sialic acid to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb57f69e94d3941971a90bfbd91d5bce
http://europepmc.org/articles/PMC7088086
http://europepmc.org/articles/PMC7088086
Polysialic acid (polySia) is a unique post-translational modification found on a small set of mammalian glycoproteins. Composed of long chains of α2,8-linked sialic acid, this large, negatively charged polymer attenuates protein and cell adhesion an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44adc8ec4471301f9ff3a6bc4fafbb4
https://europepmc.org/articles/PMC5577389/
https://europepmc.org/articles/PMC5577389/
Sequence Requirements for Neuropilin-2 Recognition by ST8SiaIV and Polysialylation of Its O-Glycans*
Polysialic acid is an oncofetal glycopolymer, added to the glycans of a small group of substrates, that controls cell adhesion and signaling. One of these substrates, neuropilin-2, is a VEGF and semaphorin co-receptor that is polysialylated on its O-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad863f4609df076c9d96b6214a1f5b7
https://europepmc.org/articles/PMC4850285/
https://europepmc.org/articles/PMC4850285/