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SOX4-SMARCA4 complex promotes glycolysis-dependent TNBC cell growth through transcriptional regulation of Hexokinase 2.

Autor: Khanna P; Department of Radiation Oncology, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA.; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA., Mehta R; Department of Radiation Oncology, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA.; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA., Mehta GA; Department of Radiation Oncology, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA.; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA., Bhatt V; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA.; Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901.; Department of Chemical Biology, Rutgers Ernest Mario School of Pharmacy, Piscataway, New Jersey 08854., Guo JY; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA.; Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901.; Department of Chemical Biology, Rutgers Ernest Mario School of Pharmacy, Piscataway, New Jersey 08854., Gatza ML; Department of Radiation Oncology, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA.; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 13. Date of Electronic Publication: 2023 Sep 13.

Nuclear Receptor-Mediated Metabolic Reprogramming and the Impact on HR+ Breast Cancer.

Autor: Hussein S; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA.; Department of Radiation Oncology, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ 08903, USA., Khanna P; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA.; Department of Radiation Oncology, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ 08903, USA.; School of Arts and Sciences, Rutgers, The State University of New Jersey, New Brunswick, NJ 08903, USA., Yunus N; School of Arts and Sciences, Rutgers, The State University of New Jersey, New Brunswick, NJ 08903, USA., Gatza ML; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA.; Department of Radiation Oncology, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ 08903, USA.; School of Arts and Sciences, Rutgers, The State University of New Jersey, New Brunswick, NJ 08903, USA.

Publikováno v: Cancers [Cancers (Basel)] 2021 Sep 26; Vol. 13 (19). Date of Electronic Publication: 2021 Sep 26.

FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036.

Autor: Angus SP; Department of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA.; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, IN, USA., Stuhlmiller TJ; Department of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA., Mehta G; Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA., Bevill SM; Department of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA.; Massachusetts General Hospital, Cambridge, MA, USA., Goulet DR; Department of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA.; Koch Institute, Massachusetts Institute of Technology, Boston, MA, USA., Olivares-Quintero JF; Department of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA., East MP; Department of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA., Tanioka M; UNC Lineberger Comprehensive Cancer Center, UNC Chapel Hill, Chapel Hill, NC, USA.; Hyogo Cancer Center, Akashi, Japan., Zawistowski JS; Department of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA., Singh D; Department of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA., Sciaky N; Department of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA., Chen X; Department of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA., He X; Department of Genetics, UNC Chapel Hill, Chapel Hill, NC, USA., Rashid NU; UNC Lineberger Comprehensive Cancer Center, UNC Chapel Hill, Chapel Hill, NC, USA.; Department of Biostatistics, UNC Chapel Hill, Chapel Hill, NC, USA., Chollet-Hinton L; UNC Lineberger Comprehensive Cancer Center, UNC Chapel Hill, Chapel Hill, NC, USA., Fan C; UNC Lineberger Comprehensive Cancer Center, UNC Chapel Hill, Chapel Hill, NC, USA., Soloway MG; UNC Lineberger Comprehensive Cancer Center, UNC Chapel Hill, Chapel Hill, NC, USA., Spears PA; UNC Lineberger Comprehensive Cancer Center, UNC Chapel Hill, Chapel Hill, NC, USA., Jefferys S; Department of Genetics, UNC Chapel Hill, Chapel Hill, NC, USA., Parker JS; UNC Lineberger Comprehensive Cancer Center, UNC Chapel Hill, Chapel Hill, NC, USA.; Department of Genetics, UNC Chapel Hill, Chapel Hill, NC, USA., Gallagher KK; UNC Lineberger Comprehensive Cancer Center, UNC Chapel Hill, Chapel Hill, NC, USA.; Department of Surgery, UNC Chapel Hill, Chapel Hill, NC, USA., Forero-Torres A; University of Alabama-Birmingham School of Medicine, Birmingham, AL, USA.; Seattle Genetics, Inc., Seattle, WA, USA., Krop IE; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Thompson AM; Department of Breast Surgical Oncology, MD Anderson Cancer Center, Houston, TX, USA.; Baylor College of Medicine, Houston, TX, USA., Murthy R; Department of Breast Medical Oncology, MD Anderson Cancer Center, Houston, TX, USA., Gatza ML; Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA., Perou CM; UNC Lineberger Comprehensive Cancer Center, UNC Chapel Hill, Chapel Hill, NC, USA.; Department of Genetics, UNC Chapel Hill, Chapel Hill, NC, USA., Earp HS; Department of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA.; UNC Lineberger Comprehensive Cancer Center, UNC Chapel Hill, Chapel Hill, NC, USA.; Department of Medicine, UNC Chapel Hill, Chapel Hill, NC, USA., Carey LA; UNC Lineberger Comprehensive Cancer Center, UNC Chapel Hill, Chapel Hill, NC, USA.; Department of Medicine, UNC Chapel Hill, Chapel Hill, NC, USA., Johnson GL; Department of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA. glj@med.unc.edu.; UNC Lineberger Comprehensive Cancer Center, UNC Chapel Hill, Chapel Hill, NC, USA. glj@med.unc.edu.

Publikováno v: NPJ breast cancer [NPJ Breast Cancer] 2021 May 12; Vol. 7 (1), pp. 51. Date of Electronic Publication: 2021 May 12.