Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Gataree, Ngarmchamnanrith"'
Autor:
Hamid R. Amouzadeh, Isaiah Dimery, Jonathan Werner, Gataree Ngarmchamnanrith, Michael J Engwall, Hugo M. Vargas, Deborah Arrindell
Publikováno v:
Translational Oncology, Vol 12, Iss 10, Pp 1296-1304 (2019)
Off-target activities of drug candidates observed during in vitro pharmacological profiling frequently do not translate to adverse events (AEs) in human. This could be because off-target activities do not have functional consequences, are not observe
Externí odkaz:
https://doaj.org/article/56cc11ab4f8a45ae841a6b7a14ff28a5
Autor:
Ben Tran, Richard D. Carvajal, Aurelien Marabelle, Sandip Pravin Patel, Patricia M. LoRusso, Erik Rasmussen, Gloria Juan, Vijay V. Upreti, Courtney Beers, Gataree Ngarmchamnanrith, Patrick Schöffski
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-9 (2018)
Abstract Background This open-label, first-in-human, phase 1 study evaluated the safety, pharmacokinetics, pharmacodynamics, and maximum tolerated dose (MTD) of AMG 228, an agonistic human IgG1 monoclonal antibody targeting glucocorticoid-induced tum
Externí odkaz:
https://doaj.org/article/c2fbc142a7e5490699bc7de71158c8cb
Autor:
Marwan G Fakih, Scott Kopetz, Yasutoshi Kuboki, Tae Won Kim, Pamela N Munster, John C Krauss, Gerald S Falchook, Sae-Won Han, Volker Heinemann, Kei Muro, John H Strickler, David S Hong, Crystal S Denlinger, Gustavo Girotto, Myung-Ah Lee, Haby Henary, Qui Tran, Joseph K Park, Gataree Ngarmchamnanrith, Hans Prenen, Timothy J Price
Publikováno v:
The lancet oncology
Background Sotorasib, a specific, irreversible KRAS(G12C) protein inhibitor, has shown monotherapy clinical activity in KRAS(G12C)-mutated solid tumours, including colorectal cancer, in the CodeBreaK100 phase 1 trial. We aimed to investigate the acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c8895175769c7fb8e15873f4aba538
https://doi.org/10.1016/s1470-2045(21)00605-7
https://doi.org/10.1016/s1470-2045(21)00605-7
Autor:
Eunice L. Kwak, Gataree Ngarmchamnanrith, Rui Tang, Yuying C. Hwang, Benny M. Amore, Robert D. Loberg, Shirish M. Gadgeel, Tanios Bekaii-Saab, Emily Chan, Daniel V.T. Catenacci, Muaiad Kittaneh, Filip Janku, Omid Hamid, Patricia LoRusso, David S. Hong
Purpose:This first-in-human, open-label phase I study evaluated AMG 337, an oral, highly selective small-molecule inhibitor of MET in advanced solid tumors.Patients and Methods: Patients enrolled into dose-escalation cohorts received AMG 337 up to 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4174a7abe84e5f1a4d99e61d73ceae4c
https://doi.org/10.1158/1078-0432.c.6528722.v1
https://doi.org/10.1158/1078-0432.c.6528722.v1
Autor:
Joe Stephenson, John S. Hill, Dirk Nagorsen, Benny M. Amore, Erik Rasmussen, Gataree Ngarmchamnanrith, Anthony W. Tolcher, Anthony J. Olszanski, Lainie P. Martin, Larry Gluck, Kyriakos P. Papadopoulos
The Supplementary Material includes the full inclusion and exclusion criteria and additional methods for the skin punch biopsy. Supplementary Table 1 lists AMG 820 pharmacokinetic parameters, Figure S1 shows AMG 820 trough concentrations, Figure S2 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5621e57627366aeb6f38a0b183ce9db4
https://doi.org/10.1158/1078-0432.22467243.v1
https://doi.org/10.1158/1078-0432.22467243.v1
Autor:
Joe Stephenson, John S. Hill, Dirk Nagorsen, Benny M. Amore, Erik Rasmussen, Gataree Ngarmchamnanrith, Anthony W. Tolcher, Anthony J. Olszanski, Lainie P. Martin, Larry Gluck, Kyriakos P. Papadopoulos
Purpose: Binding of colony-stimulating factor 1 (CSF1) ligand to the CSF1 receptor (CSF1R) regulates survival of tumor-associated macrophages, which generally promote an immunosuppressive tumor microenvironment. AMG 820 is an investigational, fully h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57de853896f3132e4a75963ca3f7eb57
https://doi.org/10.1158/1078-0432.c.6526587
https://doi.org/10.1158/1078-0432.c.6526587
Autor:
Eunice L. Kwak, Gataree Ngarmchamnanrith, Rui Tang, Yuying C. Hwang, Benny M. Amore, Robert D. Loberg, Shirish M. Gadgeel, Tanios Bekaii-Saab, Emily Chan, Daniel V.T. Catenacci, Muaiad Kittaneh, Filip Janku, Omid Hamid, Patricia LoRusso, David S. Hong
Supplementary Material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096ba55500e189f615eb7c2718080d51
https://doi.org/10.1158/1078-0432.22474214
https://doi.org/10.1158/1078-0432.22474214
Autor:
John H. Strickler, Hironaga Satake, Thomas J. George, Rona Yaeger, Antoine Hollebecque, Ignacio Garrido-Laguna, Martin Schuler, Timothy F. Burns, Andrew L. Coveler, Gerald S. Falchook, Mark Vincent, Yu Sunakawa, Laetitia Dahan, David Bajor, Sun-Young Rha, Charlotte Lemech, Dejan Juric, Marko Rehn, Gataree Ngarmchamnanrith, Pegah Jafarinasabian, Qui Tran, David S. Hong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ed72e59de17abebe165b0ec95b371a
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85145641438
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85145641438
Autor:
John H, Strickler, Hironaga, Satake, Thomas J, George, Rona, Yaeger, Antoine, Hollebecque, Ignacio, Garrido-Laguna, Martin, Schuler, Timothy F, Burns, Andrew L, Coveler, Gerald S, Falchook, Mark, Vincent, Yu, Sunakawa, Laetitia, Dahan, David, Bajor, Sun-Young, Rha, Charlotte, Lemech, Dejan, Juric, Marko, Rehn, Gataree, Ngarmchamnanrith, Pegah, Jafarinasabian, Qui, Tran, David S, Hong
Publikováno v:
The New England journal of medicine. 388(1)
We conducted a single-group, phase 1-2 trial to assess the safety and efficacy of sotorasib treatment in patients withThe pooled population from phases 1 and 2 consisted of 38 patients, all of whom had metastatic disease at enrollment and had previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::690fa07411e695496d827dfc6df6ba2f
https://pubmed.ncbi.nlm.nih.gov/36546651
https://pubmed.ncbi.nlm.nih.gov/36546651
Autor:
Jin Wang, Hisaki Fujii, Andrew Spencer, Vijay V. Upreti, Xuguang Hu, Ola Landgren, Gataree Ngarmchamnanrith, Erik Rasmussen, Hans C. Lee, Ariel A. Avilion, Noopur Raje
Publikováno v:
Leukemia. 35:255-258
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99b6a2038b864f12cc84ac82c52bdb1b
https://doi.org/10.1038/s41375-020-0834-9
https://doi.org/10.1038/s41375-020-0834-9