Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gatambwa Mukandala"'
Publikováno v:
Brain Sciences, Vol 6, Iss 1, p 6 (2016)
Normal brain function is highly dependent on oxygen and nutrient supply and when the demand for oxygen exceeds its supply, hypoxia is induced. Acute episodes of hypoxia may cause a depression in synaptic activity in many brain regions, whilst prolong
Externí odkaz:
https://doaj.org/article/66ea7e3253aa4037820e9985c699b833
In the CNS short episodes of acute hypoxia can result in a decrease in synaptic transmission which may be fully reversible upon re-oxygenation. Stabilization of hypoxia-inducible factor (HIF) by inhibition of prolyl hydroxylase domain (PHD) enzymes h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a848ed32ca3dc2886e6588fa5a2011d
Publikováno v:
Journal of Neuroscience Research. 93:815-829
An inadequate supply of oxygen in the brain may lead to an inflammatory response through neuronal and glial cells that can result in neuronal damage. Tumor necrosis factor-α (TNF-α) is a proinflammatory cytokine that is released during acute hypoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b28003b1b2907120a81e98bb91ce8a5
https://doi.org/10.1002/jnr.23540
https://doi.org/10.1002/jnr.23540
Autor:
Katerina Akassoglou, Alban Gaultier, Shinako Takimoto, Natacha Le Moan, Steven L. Gonias, Xiaohua Wu, Gatambwa Mukandala, W. Marie Campana
Publikováno v:
Journal of Cell Science. 122:1155-1162
Multiple sclerosis (MS) is an autoimmune disease in which myelin is progressively degraded. Because degraded myelin may both initiate and accelerate disease progression, clearing degraded myelin from extracellular spaces may be critical. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27783fa288794c991e2d61751166933a
https://doi.org/10.1242/jcs.040717
https://doi.org/10.1242/jcs.040717
Publikováno v:
Journal of Biological Chemistry. 283:19904-19911
alpha(2)-Macroglobulin (alpha(2)M) is a plasma protease inhibitor, which reversibly binds growth factors and, in its activated form, binds to low density lipoprotein receptor-related protein (LRP-1), an endocytic receptor with cell signaling activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d1f00b2ec7d0680ac76ea061d0eb90
https://doi.org/10.1074/jbc.m801762200
https://doi.org/10.1074/jbc.m801762200
Publikováno v:
Journal of neuroscience research. 93(5)
An inadequate supply of oxygen in the brain may lead to the introduction of an inflammatory response through neuronal and glial cells that can result in neuronal damage. Tumor necrosis factor alpha (TNF-α) is a pro-inflammatory cytokine that is rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac0637859a147d792177aea5e9bff943
https://pubmed.ncbi.nlm.nih.gov/25641742
https://pubmed.ncbi.nlm.nih.gov/25641742
Publikováno v:
Brain Sciences
Brain Sciences, Vol 6, Iss 1, p 6 (2016)
Brain Sciences, Vol 6, Iss 1, p 6 (2016)
Normal brain function is highly dependent on oxygen and nutrient supply and when the demand for oxygen exceeds its supply, hypoxia is induced. Acute episodes of hypoxia may cause a depression in synaptic activity in many brain regions, whilst prolong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7107b373242ad11fa94a267a2210561
https://doi.org/10.3390/brainsci6010006
https://doi.org/10.3390/brainsci6010006