The Amaryllidaceae alkaloid, montanine, is a potential inhibitor of the Trypanosoma cruzi trans-sialidase enzyme.

Autor: Manu P; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Mensah JO; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Gasu EN; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; Central Laboratory, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Borquaye LS; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; Central Laboratory, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Publikováno v: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 Oct; Vol. 42 (17), pp. 8920-8936. Date of Electronic Publication: 2023 Oct 23.

Antileishmanial natural products as potential inhibitors of the Leishmania pteridine reductase: insights from molecular docking and molecular dynamics simulations.

Autor: Adomako AK; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Gasu EN; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; Central Laboratory, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Mensah JO; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Borquaye LS; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; Central Laboratory, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Publikováno v: In silico pharmacology [In Silico Pharmacol] 2024 Jul 30; Vol. 12 (2), pp. 70. Date of Electronic Publication: 2024 Jul 30 (Print Publication: 2024).

Molecular insights into the differential membrane targeting of maximin 1 in prokaryotic and eukaryotic cells.

Autor: Mensah JO; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Boakye A; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Laryea M; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Gasu EN; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Borquaye LS; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; Central Laboratory, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Publikováno v: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2023 Dec 12, pp. 1-14. Date of Electronic Publication: 2023 Dec 12.

Computational studies on potential small molecule inhibitors of Leishmania pteridine reductase 1.

Autor: Boakye A; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Gasu EN; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; Central Laboratory, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Mensah JO; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Borquaye LS; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; Central Laboratory, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Publikováno v: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2023; Vol. 41 (21), pp. 12128-12141. Date of Electronic Publication: 2023 Jan 12.

Alkaloids from Cryptolepis sanguinolenta as Potential Inhibitors of SARS-CoV-2 Viral Proteins: An In Silico Study.

Autor: Borquaye LS; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; Central Laboratory, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Gasu EN; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; Central Laboratory, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Ampomah GB; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Kyei LK; Central Laboratory, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Amarh MA; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Mensah CN; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Nartey D; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Commodore M; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Adomako AK; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Acheampong P; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Mensah JO; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Mormor DB; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Aboagye CI; Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Publikováno v: BioMed research international [Biomed Res Int] 2020 Sep 22; Vol. 2020, pp. 5324560. Date of Electronic Publication: 2020 Sep 22 (Print Publication: 2020).