Zobrazeno 1 - 10
of 1 052
pro vyhledávání: '"Gastrin-releasing peptide receptor"'
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
AbstractAim: This comprehensive review aims to explore the potential applications of Gastrin-releasing peptide receptor (GRPR) in the diagnosis and treatment of prostate cancer. Additionally, the study investigates the role of GRPR in prognostic asse
Externí odkaz:
https://doaj.org/article/65af275c981f4ff3991a38bbf8f9cf4f
Autor:
Lei Wang, Hsiou-Ting Kuo, Zhengxing Zhang, Chengcheng Zhang, Chao-Cheng Chen, Devon Chapple, Ryan Wilson, Nadine Colpo, François Bénard, Kuo-Shyan Lin
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Background Overexpressed in various solid tumors, gastrin-releasing peptide receptor (GRPR) is a promising cancer imaging marker and therapeutic target. Although antagonists are preferable for the development of GRPR-targeted radiopharmaceut
Externí odkaz:
https://doaj.org/article/24ff8b25475b4173968a9c483ac5e550
Autor:
Maria Bibika, Panagiotis Kanellopoulos, Maritina Rouchota, George Loudos, Berthold A. Nock, Eric P. Krenning, Theodosia Maina
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1223 (2024)
Background: The concept of radiotheranostics relies on the overexpression of a biomolecular target on malignant cells to direct diagnostic/therapeutic radionuclide-carriers specifically to cancer lesions. The concomitant expression of more than one t
Externí odkaz:
https://doaj.org/article/95e76b12426f4ce9b6e24d4e6a8838e3
Autor:
Hang Xu, Ping Yu, Rajendra P. Bandari, Charles J. Smith, Michael R. Aro, Amolak Singh, Lixin Ma
Publikováno v:
Nanomaterials, Vol 14, Iss 14, p 1177 (2024)
We developed a novel site-specific bimodal MRI/fluorescence nanoparticle contrast agent targeting gastrin-releasing peptide receptors (GRPrs), which are overexpressed in aggressive prostate cancers. Biocompatible ultra-small superparamagnetic iron ox
Externí odkaz:
https://doaj.org/article/ad6ff45980e44c6e98a4f22cf155c7b6
Autor:
Lei Wang, Hsiou-Ting Kuo, Chao-Cheng Chen, Devon Chapple, Nadine Colpo, Pauline Ng, Wing Sum Lau, Shireen Jozi, François Bénard, Kuo-Shyan Lin
Publikováno v:
Molecules, Vol 29, Iss 13, p 3102 (2024)
Gastrin-releasing peptide receptor (GRPR), overexpressed in many solid tumors, is a promising imaging marker and therapeutic target. Most reported GRPR-targeted radioligands contain a C-terminal amide. Based on the reported potent antagonist D-Phe-Gl
Externí odkaz:
https://doaj.org/article/90a3007f690d4f83bd84d2472d76249b
Autor:
Lei Wang, Chao-Cheng Chen, Zhengxing Zhang, Hsiou-Ting Kuo, Chengcheng Zhang, Nadine Colpo, Helen Merkens, François Bénard, Kuo-Shyan Lin
Publikováno v:
Pharmaceuticals, Vol 17, Iss 5, p 621 (2024)
Gastrin-releasing peptide receptor (GRPR) is overexpressed in various cancers and is a promising target for cancer diagnosis and therapy. However, the high pancreas uptake and/or metabolic instability observed for most reported GRPR-targeted radiolig
Externí odkaz:
https://doaj.org/article/16c02e200e2b477db4930b5913cbb995
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Breast Cancer (BC) is the most common cancer worldwide and, despite the advancements made toward early diagnosis and novel treatments, there is an urgent need to reduce its mortality. The Gastrin-Releasing Peptide Receptor (GRPR) is a promising targe
Externí odkaz:
https://doaj.org/article/d800166837b94aada0fe363fec5401d8
Autor:
Marjolein Verhoeven, Eline A. M. Ruigrok, Geert J. L. H. van Leenders, Lilian van den Brink, Hayri E. Balcioglu, Wytske M. van Weerden, Simone U. Dalm
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionCentral to targeted radionuclide imaging and therapy of prostate cancer (PCa) are prostate-specific membrane antigen (PSMA)-targeting radiopharmaceuticals. Gastrin-releasing peptide receptor (GRPR) targeting has been proposed as a potenti
Externí odkaz:
https://doaj.org/article/accb1ad6d1da457fba2d6b246b633125
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Akademický článek
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