Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Gastric Inhibitory Polypeptide/blood"'
Autor:
Anna Jonsson, Peter Weeke, Jørgen K. Kanters, Jens J. Holst, Henrik Vestergaard, Torben Hansen, Yuvaraj Mahendran, Signe S. Torekov, Daniel R. Witte, Line Engelbrechtsen, Oluf Pedersen, Marit E. Jørgensen, Kristine Færch, Niels Grarup, Anette P. Gjesing, Torben Jørgensen
Publikováno v:
Engelbrechtsen, L, Mahendran, Y, Jonsson, A, Gjesing, A P, Weeke, P E, Jørgensen, M E, Færch, K, Witte, D R, Holst, J J, Jørgensen, T, Grarup, N, Pedersen, O, Vestergaard, H, Torekov, S, Kanters, J K & Hansen, T 2018, ' Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses ', B M C Genetics, vol. 19, no. 1, 15, pp. 1-9 . https://doi.org/10.1186/s12863-018-0602-2
Engelbrechtsen, L, Mahendran, Y, Jonsson, A, Gjesing, A P, Weeke, P E, Jørgensen, M E, Færch, K, Witte, D R, Holst, J J, Jørgensen, T, Grarup, N, Pedersen, O, Vestergaard, H, Torekov, S, Kanters, J K & Hansen, T 2018, ' Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses ', BMC Genetics, vol. 19, 15 . https://doi.org/10.1186/s12863-018-0602-2
BMC Genetics, Vol 19, Iss 1, Pp 1-9 (2018)
Engelbrechtsen, L, Mahendran, Y, Jonsson, A, Gjesing, A P, Weeke, P E, Jørgensen, M E, Færch, K, Witte, D R, Holst, J J, Jørgensen, T, Grarup, N, Pedersen, O, Vestergaard, H, Torekov, S, Kanters, J K & Hansen, T 2018, ' Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses ', B M C Genetics, vol. 19, no. 1, 15, pp. 15 . https://doi.org/10.1186/s12863-018-0602-2
Engelbrechtsen, L, Mahendran, Y, Jonsson, A, Gjesing, A P, Weeke, P E, Jørgensen, M E, Færch, K, Witte, D R, Holst, J J, Jørgensen, T, Grarup, N, Pedersen, O, Vestergaard, H, Torekov, S, Kanters, J K & Hansen, T 2018, ' Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses ', BMC Genetics, vol. 19, no. 1, pp. 15 . https://doi.org/10.1186/s12863-018-0602-2
BMC Genetics
Engelbrechtsen, L, Mahendran, Y, Jonsson, A, Gjesing, A P, Weeke, P E, Jørgensen, M E, Færch, K, Witte, D R, Holst, J J, Jørgensen, T, Grarup, N, Pedersen, O, Vestergaard, H, Torekov, S, Kanters, J K & Hansen, T 2018, ' Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses ', BMC Genetics, vol. 19, 15 . https://doi.org/10.1186/s12863-018-0602-2
BMC Genetics, Vol 19, Iss 1, Pp 1-9 (2018)
Engelbrechtsen, L, Mahendran, Y, Jonsson, A, Gjesing, A P, Weeke, P E, Jørgensen, M E, Færch, K, Witte, D R, Holst, J J, Jørgensen, T, Grarup, N, Pedersen, O, Vestergaard, H, Torekov, S, Kanters, J K & Hansen, T 2018, ' Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses ', B M C Genetics, vol. 19, no. 1, 15, pp. 15 . https://doi.org/10.1186/s12863-018-0602-2
Engelbrechtsen, L, Mahendran, Y, Jonsson, A, Gjesing, A P, Weeke, P E, Jørgensen, M E, Færch, K, Witte, D R, Holst, J J, Jørgensen, T, Grarup, N, Pedersen, O, Vestergaard, H, Torekov, S, Kanters, J K & Hansen, T 2018, ' Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses ', BMC Genetics, vol. 19, no. 1, pp. 15 . https://doi.org/10.1186/s12863-018-0602-2
BMC Genetics
Background Patients with long QT syndrome due to rare loss-of-function mutations in the human ether-á-go-go-related gene (hERG) have prolonged QT interval, risk of arrhythmias, increased secretion of insulin and incretins and impaired glucagon respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665a5c8aa6803c6af810b746f20a8dcd
https://curis.ku.dk/ws/files/209465573/Engelbrechtsen_BMC.pdf
https://curis.ku.dk/ws/files/209465573/Engelbrechtsen_BMC.pdf
Autor:
Thomas Jespersen, Bolette Hartmann, Michael Christiansen, Nicolai J. Wewer Albrechtsen, Jørgen K. Kanters, Torben Hansen, Allan Linneberg, Eva W. Iepsen, Anniek F. Lubberding, Jens J. Holst, Henrik Vestergaard, Oluf Pedersen, Signe S. Torekov, Mathilde Svendstrup, Louise Hyltén-Cavallius
Publikováno v:
Hyltén-Cavallius, L, Iepsen, E W, Wewer Albrechtsen, N J, Svendstrup, M, Lubberding, A F, Hartmann, B, Jespersen, T, Linneberg, A, Christiansen, M, Vestergaard, H, Pedersen, O, Holst, J J, Kanters, J K, Hansen, T & Torekov, S S 2017, ' Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia ', Circulation, vol. 135, no. 18, pp. 1705-1719 . https://doi.org/10.1161/CIRCULATIONAHA.116.024279
Hyltén-Cavallius, L, Iepsen, E W, Wewer Albrechtsen, N J, Svendstrup, M, Lubberding, A F, Hartmann, B, Jespersen, T, Linneberg, A, Christiansen, M, Vestergaard, H, Pedersen, O, Holst, J J, Kanters, J K, Hansen, T & Torekov, S 2017, ' Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia ', Circulation, vol. 135, no. 18, pp. 1705-1719 . https://doi.org/10.1161/CIRCULATIONAHA.116.024279
Hyltén-Cavallius, L, Iepsen, E W, Wewer Albrechtsen, N J, Svendstrup, M, Lubberding, A F, Hartmann, B, Jespersen, T, Linneberg, A, Christiansen, M, Vestergaard, H, Pedersen, O, Holst, J J, Kanters, J K, Hansen, T & Torekov, S S 2017, ' Patients with Long-QT Syndrome Caused by Impaired hERG-Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia ', Circulation, vol. 135, no. 18, pp. 1705-1719 . https://doi.org/10.1161/CIRCULATIONAHA.116.024279
Hyltén-Cavallius, L, Iepsen, E W, Wewer Albrechtsen, N J, Svendstrup, M, Lubberding, A F, Hartmann, B, Jespersen, T, Linneberg, A, Christiansen, M, Vestergaard, H, Pedersen, O, Holst, J J, Kanters, J K, Hansen, T & Torekov, S 2017, ' Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia ', Circulation, vol. 135, no. 18, pp. 1705-1719 . https://doi.org/10.1161/CIRCULATIONAHA.116.024279
Hyltén-Cavallius, L, Iepsen, E W, Wewer Albrechtsen, N J, Svendstrup, M, Lubberding, A F, Hartmann, B, Jespersen, T, Linneberg, A, Christiansen, M, Vestergaard, H, Pedersen, O, Holst, J J, Kanters, J K, Hansen, T & Torekov, S S 2017, ' Patients with Long-QT Syndrome Caused by Impaired hERG-Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia ', Circulation, vol. 135, no. 18, pp. 1705-1719 . https://doi.org/10.1161/CIRCULATIONAHA.116.024279
Background: Loss-of-function mutations in hERG (encoding the K v 11.1 voltage-gated potassium channel) cause long-QT syndrome type 2 (LQT2) because of prolonged cardiac repolarization. However, K v 11.1 is also present in pancreatic α and β cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa3e5dfa6db2db84dd560e5c140b9ca
https://curis.ku.dk/portal/da/publications/patients-with-long-qt-syndrome-due-to-impaired-hergencoded-kv111-potassium-channel-have-exaggerated-endocrine-pancreatic-and-incretin-function-associated-with-reactive-hypoglycemia(b3415700-4dc0-4294-a7bc-f0de156cbde2).html
https://curis.ku.dk/portal/da/publications/patients-with-long-qt-syndrome-due-to-impaired-hergencoded-kv111-potassium-channel-have-exaggerated-endocrine-pancreatic-and-incretin-function-associated-with-reactive-hypoglycemia(b3415700-4dc0-4294-a7bc-f0de156cbde2).html