Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gaston Stanislas Marcell Diels"'
Autor:
Jan Jacobs, Norbert De Kimpe, Bart Kesteleyn, Gaston Stanislas Marcell Diels, Blaise Mavinga Mbala
Publikováno v:
Tetrahedron. 64:6364-6371
Related to our research on structural modifications of pentalongin, the active principle of the medicinal plant Pentas longiflora Oliv., a new synthesis of N -protected 1,2-dihydrobenz[ g ]isoquinoline-5,10-diones and their 4-methyl derivatives, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f982fcde8666f134ed772408b9467ee4
https://doi.org/10.1016/j.tet.2008.04.083
https://doi.org/10.1016/j.tet.2008.04.083
Autor:
Alex De Groot, Joannes Theodorus Maria Linders, Paul de Belser, Libuse Jaroskova, Louis Jozef Elisabeth Van Der Veken, Gaston Stanislas Marcell Diels
Publikováno v:
Tetrahedron Letters. 47:8063-8067
Reductive amination of 5-hydroxy-2-adamantanone with S-α-methylbenzylamine using 5% Rh–C as the catalyst in the presence of Al(iOPr)3 gave a 3:1 mixture of the E- and Z-5-hydroxy-adamantane-1-phenethylamines. Choice of catalyst, concentration, sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a28fd2b2765407ab7a924d6210a1ea39
https://doi.org/10.1016/j.tetlet.2006.09.056
https://doi.org/10.1016/j.tetlet.2006.09.056
Autor:
Kristof T. J. Loones, Gaston Stanislas Marcell Diels, Geert Rombouts, Steven Hostyn, Bert U. W. Maes
Publikováno v:
Tetrahedron
Batch wise scale-up of Buchwald–Hartwig aminations under microwave irradiation has been investigated for the first time. Multi-mode (microSYNTH and MARS) (several vessels irradiated in parallel per batch) as well as single-mode (Discover) (one vess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4027a2d97cf584713a2833c9bf0c4f8d
https://doi.org/10.1016/j.tet.2005.07.105
https://doi.org/10.1016/j.tet.2005.07.105
Norpiperidine Imidazoazepines as a New Class of Potent, Selective, and Nonsedative H1 Antihistamines
Autor:
Marcel Borgers, Jos Leenaerts, Janssens Frans Eduard, Xavier Langlois, Johan Beetens, Koen van Rossem, Gaston Stanislas Marcell Diels, Benoit Christian Albert Ghislain De Boeck, Anton Megens
Publikováno v:
Journal of Medicinal Chemistry. 48:2154-2166
Clinical doses of available H(1) antihistamines are limited mainly by sedative side effects. However, higher doses are often required to obtain optimal therapeutic activity, especially in dermatology. We report the synthesis of three norpiperidine im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e791d89f2b1876057025ee720647ddc6
https://doi.org/10.1021/jm049495j
https://doi.org/10.1021/jm049495j
Publikováno v:
QSAR & Combinatorial Science. 23:906-910
One of the major issues associated to microwave assisted organic chemistry is reproducibility. In the present article we demonstrate that reproducibility of results can be obtained from commercially available single-mode and multimode microwave react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8843a175aba6073a9fafaf7709aedfc3
https://doi.org/10.1002/qsar.200420035
https://doi.org/10.1002/qsar.200420035
Autor:
Steven Hostyn, Kristof T. J. Loones, Gaston Stanislas Marcell Diels, Geert Rombouts, Bert U. W. Maes
Publikováno v:
Tetrahedron
Rapid Buchwald–Hartwig amination of electron neutral and rich aryl chlorides and bromides have been achieved using temperature-controlled microwave heating. Primary and secondary aliphatic amines can be coupled with these substrates in good yields
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48d0588305be2652118569feea1eed8
https://doi.org/10.1016/j.tet.2004.09.071
https://doi.org/10.1016/j.tet.2004.09.071
Publikováno v:
Scopus-Elsevier
ARKIVOC, Vol 2003, Iss 4, Pp 46-50 (2003)
ARKIVOC, Vol 2003, Iss 4, Pp 46-50 (2003)
A one step synthesis of (±)-all-cis-1,2,4-cyclohexanetriol 1 by high pressure hydrogenation of the corresponding 1,2,4-benzenetriol in the presence of Raney-nickel or a catalytic amount of rhodium on aluminium oxide is disclosed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b569870b1abdcb2549de6324a4417b
https://doi.org/10.3998/ark.5550190.0004.404
https://doi.org/10.3998/ark.5550190.0004.404
Autor:
Luc Verschaeve, Sven Claessens, Roel Anthonissen, Tuyen Nguyen Van, Davie Cappoen, Maryse Fauville, Kris Huygen, Thorbjorg Einarsdottir, Norbert De Kimpe, Jan Jacobs, Gaston Stanislas Marcell Diels
Publikováno v:
European journal of medicinal chemistry. 48
In 1991, WHO recognized the resurgence of tuberculosis as a global health problem. Although modern chemotherapy is effective against the causative pathogen Mycobacterium tuberculosis, the current drug regimens have failed to eradicate the disease. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159714b3b64dbe07c0595b58ac3849c2
https://pubmed.ncbi.nlm.nih.gov/22182928
https://pubmed.ncbi.nlm.nih.gov/22182928
Publikováno v:
ChemInform. 38
Microwave irradiation has been used to enhance organic reactions since the mid 80s, its use within the field of medicinal chemistry is not so widely evident in the literature. The present review highlights the use of microwave chemistry as an importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cd8c0328e583b67b50bb69316045dba
https://doi.org/10.1002/chin.200731241
https://doi.org/10.1002/chin.200731241
Publikováno v:
Mini reviews in medicinal chemistry. 7(4)
Microwave irradiation has been used to enhance organic reactions since the mid 80's, its use within the field of medicinal chemistry is not so widely evident in the literature. The present review highlights the use of microwave chemistry as an import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658ca7282036c8e6e03ecfc85a381eb5
https://pubmed.ncbi.nlm.nih.gov/17430222
https://pubmed.ncbi.nlm.nih.gov/17430222