Length-limitation of astral microtubules orients cell divisions in intestinal crypts

Autor: Saleh Jad, Fardin Marc-Antoine, Frenoy Olivia, Soleilhac Matis, Gaston Cécile, Cui Hongyue, Dang Tien, Noémie Gaudin, Vincent Audrey, Minc Nicolas, Delacour Delphine

Publikováno v: BioRxiv
BioRxiv, 2022, ⟨10.1101/2022.09.02.506333⟩

SUMMARYPlanar spindle orientation is critical for epithelial tissue organization, and generally instructed from the long cell shape axis or cortical polarity domains. We introduced mouse intestinal organoid crypts to study spindle orientation in a mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2514cf8b047e2c2088afbbe3b7f627cd
https://doi.org/10.1101/2022.09.02.506333

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Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity

Autor: Salomon, Julie, Gaston, Cécile, Magescas, Jérémy, Duvauchelle, Boris, Canioni, Danielle, Sengmanivong, Lucie, Mayeux, Adeline, Michaux, Grégoire, Campeotto, Florence, Lemale, Julie, Viala, Jérôme, Poirier, Françoise, Minc, Nicolas, Schmitz, Jacques, Brousse, Nicole, Ladoux, Benoit, Goulet, Olivier, Delacour, Delphine

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8 (1), pp.13998. ⟨10.1038/ncomms13998⟩
Nature Communications, Nature Publishing Group, 2017, 8, pp.13998. 〈10.1038/ncomms13998〉
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)

Monolayered epithelia are composed of tight cell assemblies that ensure polarized exchanges. EpCAM, an unconventional epithelial-specific cell adhesion molecule, is assumed to modulate epithelial morphogenesis in animal models, but little is known re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1d8d3e01e81449bab39f99600d2d165f
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01439356

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Galectin-3 modulates epithelial cell adaptation to stress at the ER-mitochondria interface.

Autor: Coppin L; University of Lille, CNRS, Inserm, CHU Lille, UMR9020 - UMR-S 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000, Lille, France., Jannin A; University of Lille, CNRS, Inserm, CHU Lille, UMR9020 - UMR-S 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000, Lille, France., Ait Yahya E; CHU Lille, Institut de Biochimie & Biologie Moléculaire, Centre de Biologie et Pathologie, F-59000, Lille, France., Thuillier C; CHU Lille, Institut de Génétique, Centre de Biologie et Pathologie, F-59000, Lille, France., Villenet C; University of Lille, CHU Lille, Plate-forme de génomique fonctionnelle, Centre de Biologie et Pathologie, F-59000, Lille, France., Tardivel M; University of Lille, F-59000, Lille, France., Bongiovanni A; University of Lille, F-59000, Lille, France., Gaston C; Equipe Cell adhesion and mechanics, Institut Jacques Monod - UMR 7592 CNRS - Université Paris Diderot, F-75205, Paris Cedex 13, France., de Beco S; Equipe Cell adhesion and mechanics, Institut Jacques Monod - UMR 7592 CNRS - Université Paris Diderot, F-75205, Paris Cedex 13, France., Barois N; University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Center for Infection and Immunity of Lille, F-59000, Lille, France., van Seuningen I; University of Lille, CNRS, Inserm, CHU Lille, UMR9020 - UMR-S 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000, Lille, France., Durand E; University of Lille, CNRS, CHU Lille, Institut Pasteur de Lille, UMR 8199, EGID, F-59000, Lille, France., Bonnefond A; University of Lille, CNRS, CHU Lille, Institut Pasteur de Lille, UMR 8199, EGID, F-59000, Lille, France., Vienne JC; CHU Lille, Institut de Biochimie & Biologie Moléculaire, Centre de Biologie et Pathologie, F-59000, Lille, France., Vamecq J; CHU Lille, Institut de Biochimie & Biologie Moléculaire, Centre de Biologie et Pathologie, F-59000, Lille, France., Figeac M; University of Lille, CHU Lille, Plate-forme de génomique fonctionnelle, Centre de Biologie et Pathologie, F-59000, Lille, France., Vincent A; University of Lille, CNRS, Inserm, CHU Lille, UMR9020 - UMR-S 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000, Lille, France., Delacour D; Equipe Cell adhesion and mechanics, Institut Jacques Monod - UMR 7592 CNRS - Université Paris Diderot, F-75205, Paris Cedex 13, France., Porchet N; University of Lille, CNRS, Inserm, CHU Lille, UMR9020 - UMR-S 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000, Lille, France., Pigny P; University of Lille, CNRS, Inserm, CHU Lille, UMR9020 - UMR-S 1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000, Lille, France. pascal.pigny@inserm.fr.

Publikováno v: Cell death & disease [Cell Death Dis] 2020 May 12; Vol. 11 (5), pp. 360. Date of Electronic Publication: 2020 May 12.