Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase.

Autor: Hicks KG; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA., Cluntun AA; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA., Schubert HL; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA., Hackett SR; Calico Life Sciences LLC, South San Francisco, CA, USA., Berg JA; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA., Leonard PG; Core for Biomolecular Structure and Function, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Ajalla Aleixo MA; Laboratório de Cristalografia de Proteinas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil., Zhou Y; School of Computing, University of Utah, Salt Lake City, UT, USA.; Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT, USA., Bott AJ; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA., Salvatore SR; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Chang F; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Blevins A; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA., Barta P; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA., Tilley S; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA., Leifer A; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA., Guzman A; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA., Arok A; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA., Fogarty S; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.; Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City, UT, USA., Winter JM; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA., Ahn HC; Integrated Research Institute for Drug Development, College of Pharmacy, Dongguk University-Seoul, Goyang, The Republic of Korea., Allen KN; Department of Chemistry, Boston University, Boston, MA, USA., Block S; The Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Cardoso IA; Laboratório de Cristalografia de Proteinas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil., Ding J; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Shanghai, China., Dreveny I; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, UK., Gasper WC; Department of Biology, Boston University, Boston, MA, USA., Ho Q; Department of Biology, Boston University, Boston, MA, USA., Matsuura A; Integrated Research Institute for Drug Development, College of Pharmacy, Dongguk University-Seoul, Goyang, The Republic of Korea., Palladino MJ; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA., Prajapati S; Department of Molecular Enzymology, Göttingen Center of Molecular Biosciences, University of Göttingen, Göttingen, Germany.; Department of Structural Dynamics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany., Sun P; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Shanghai, China., Tittmann K; Department of Molecular Enzymology, Göttingen Center of Molecular Biosciences, University of Göttingen, Göttingen, Germany.; Department of Structural Dynamics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany., Tolan DR; Department of Biology, Boston University, Boston, MA, USA., Unterlass J; Department of Oncology and Pathology, Karolinska Institute, Stockholm, Sweden., VanDemark AP; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, USA., Vander Heiden MG; The Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA., Webb BA; Department of Biochemistry, West Virginia University, Morgantown, WV, USA., Yun CH; Department of Biophysics, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China., Zhao P; Department of Biophysics, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China., Wang B; School of Computing, University of Utah, Salt Lake City, UT, USA.; Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT, USA., Schopfer FJ; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, Pittsburgh, PA, USA.; Pittsburgh Liver Research Center, Pittsburgh, PA, USA.; Center for Metabolism and Mitochondrial Medicine, Pittsburgh, PA, USA., Hill CP; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA., Nonato MC; Laboratório de Cristalografia de Proteinas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil., Muller FL; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Cox JE; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA., Rutter J; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.; Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2023 Mar 10; Vol. 379 (6636), pp. 996-1003. Date of Electronic Publication: 2023 Mar 09.

X-ray crystal structure of the UCS domain-containing UNC-45 myosin chaperone from Drosophila melanogaster.

Autor: Lee CF; Department of Biology, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182-1030, USA., Hauenstein AV, Fleming JK, Gasper WC, Engelke V, Sankaran B, Bernstein SI, Huxford T

Publikováno v: Structure (London, England : 1993) [Structure] 2011 Mar 09; Vol. 19 (3), pp. 397-408.