Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Gaspard Cretenet"'
Autor:
Helga Simon-Molas, Nienke Goedhart, Chiara Montironi, Gaspard Cretenet, Chaja F Jacobs, Joanne Rietveld, Eric Eldering, Arnon Kater
Publikováno v:
HemaSphere, Vol 7, p e176027a (2023)
Externí odkaz:
https://doaj.org/article/78e3460392d34f72b862d2ee8b899ca2
Autor:
Chiara Montironi, Chaja F Jacobs, Gaspard Cretenet, Fleur Peters, Arnon Kater, Helga Simon-Molas, Eric Eldering
Publikováno v:
HemaSphere, Vol 7, p e845669e (2023)
Externí odkaz:
https://doaj.org/article/fc63d90a75eb4ed5941793b017b41487
Autor:
Zhenghao Chen, Gaspard Cretenet, Valeria Carnazzo, Helga Simon-Molas, Arnon P. Kater, Gerritje J. W. van der Windt, Eric Eldering
Publikováno v:
Haematologica, Vol 109, Iss 1 (2023)
CD40 signaling upregulates BCL-XL and MCL-1 expression in the chronic lymphocytic leukemia (CLL) lymph node microenvironment, affording resistance to the BCL-2 inhibitor, venetoclax. Venetoclax resistance in the therapeutic setting and after long-ter
Externí odkaz:
https://doaj.org/article/be69defe4fa440efaf2fcbe3e5d8aab7
Autor:
Céline Jouffe, Gaspard Cretenet, Laura Symul, Eva Martin, Florian Atger, Felix Naef, Frédéric Gachon
Publikováno v:
PLoS Biology, Vol 11, Iss 1, p e1001455 (2013)
Biological rhythms play a fundamental role in the physiology and behavior of most living organisms. Rhythmic circadian expression of clock-controlled genes is orchestrated by a molecular clock that relies on interconnected negative feedback loops of
Externí odkaz:
https://doaj.org/article/3532aea0231449a6ae9ceb96b305ef92
Autor:
Zhenghao Chen, Helga Simon-Molas, Gaspard Cretenet, Beatriz Valle-Argos, Lindsay D. Smith, Francesco Forconi, Bauke V. Schomakers, Michel van Weeghel, Dean J. Bryant, Jaco A. C. van Bruggen, Fleur S. Peters, Jeffrey C. Rathmell, Gerritje J. W. van der Windt, Arnon P. Kater, Graham Packham, Eric Eldering
Publikováno v:
Blood, 140(6), 630-643. American Society of Hematology
Chen, Z, Simon-Molas, H, Cretenet, G, Valle-Argos, B, Smith, L D, Forconi, F, Schomakers, B V, van Weeghel, M, Bryant, D J, van Bruggen, J A C, Peters, F S, Rathmell, J C, van der Windt, G J W, Kater, A P, Packham, G & Eldering, E 2022, ' Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment ', Blood, vol. 140, no. 6, pp. 630-643 . https://doi.org/10.1182/blood.2021013990
Chen, Z, Simon-Molas, H, Cretenet, G, Valle-Argos, B, Smith, L D, Forconi, F, Schomakers, B V, van Weeghel, M, Bryant, D J, van Bruggen, J A C, Peters, F S, Rathmell, J C, van der Windt, G J W, Kater, A P, Packham, G & Eldering, E 2022, ' Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment ', Blood, vol. 140, no. 6, pp. 630-643 . https://doi.org/10.1182/blood.2021013990
Altered metabolism is a hallmark of both cell division and cancer. Chronic lymphocytic leukemia (CLL) cells circulate between peripheral blood (PB) and lymph nodes (LNs), where they receive proliferative and prosurvival signals from surrounding cells
Autor:
Chaja Feige Jacobs, Fleur Peters, Gaspard Cretenet, Eric Eldering, Noam Zelcer, Arnon P. Kater, Helga Simon-Molas
Publikováno v:
Blood. 140:6998-6999
Autor:
Jaco A.C. Van Bruggen, Fleur Peters, Joanne M. Rietveld, Gaspard Cretenet, Joseph Melenhorst, Eric Eldering, Arnon P. Kater
Publikováno v:
Blood. 140:12688-12689
Autor:
Sriram Balasubramanian, Arnon P. Kater, Joel Leverson, Gaspard Cretenet, Eric Eldering, Anne W. J. Martens, Erik Slinger
Publikováno v:
Blood, 5(23), 5410-5414. American Society of Hematology
Blood advances, 5(23), 5410-5414. American Society of Hematology
Kater, A P, Slinger, E, Cretenet, G, Martens, A W, Balasubramanian, S, Leverson, J D & Eldering, E 2021, ' Combined ibrutinib and venetoclax treatment vs single agents in the TCL1 mouse model of chronic lymphocytic leukemia ', Blood, vol. 5, no. 23, pp. 5410-5414 . https://doi.org/10.1182/bloodadvances.2021004861
Blood advances, 5(23), 5410-5414. American Society of Hematology
Kater, A P, Slinger, E, Cretenet, G, Martens, A W, Balasubramanian, S, Leverson, J D & Eldering, E 2021, ' Combined ibrutinib and venetoclax treatment vs single agents in the TCL1 mouse model of chronic lymphocytic leukemia ', Blood, vol. 5, no. 23, pp. 5410-5414 . https://doi.org/10.1182/bloodadvances.2021004861
The covalent inhibitor of Bruton’s tyrosine kinase ibrutinib and the specific Bcl-2 inhibitor venetoclax are both highly efficacious single-agent drugs in the treatment of chronic lymphocytic leukemia (CLL). Based on their complementary modes of ac
Autor:
Arnon P. Kater, Jaco A. C. van Bruggen, Gaspard Cretenet, J. Joseph Melenhorst, Eric Eldering, Fleur S. Peters
Publikováno v:
Blood. 138:3714-3714
Introduction Success rates of autologous T cell-based therapies, such as CAR-T cell therapy, in chronic lymphocytic leukemia (CLL) have been suboptimal and correlate with failure of activation and proliferation of T cells in vitro and in vivo. Previo
Autor:
Gerritje J. W. van der Windt, Helga Simon-Molas, Michel van Weeghel, Dean Bryant, Arnon P. Kater, Beatriz Valle-Argos, Graham Packham, Jaco A. C. van Bruggen, Fleur S. Peters, Gaspard Cretenet, Bauke V. Schomakers, Eric Eldering, Francesco Forconi, Zhenghao Chen
Publikováno v:
Blood. 138:3717-3717
Introduction: For chronic lymphocytic leukemia (CLL), especially in the lymph node (LN) setting where cells receive proliferative and pro-survival signals, in-depth studies of altered metabolism and its relationship with therapeutic responses are sti