Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gaspar Peña-Münzenmayer"'
Autor:
José Sarmiento, Marcelo A. Catalán, Gaspar Peña-Münzenmayer, Constanza Salinas, Yusuke Kondo, Sebastian Brauchi
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Ae4 transporters are critical for Cl(−) uptake across the basolateral membrane of acinar cells in the submandibular gland (SMG). Although required for fluid secretion, little is known about the physiological regulation of Ae4. To investigate whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff48ffc766d606e5ad6666c25e822c8d
https://europepmc.org/articles/PMC8887885/
https://europepmc.org/articles/PMC8887885/
Publikováno v:
The Journal of General Physiology
AE4 is an anion exchanger known to counter transport Cl− and HCO3− across secretory cell membranes. Peña-Münzenmayer et al. show that AE4 is an electroneutral exchanger and that it also transports monovalent cations in the same direction as HCO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee6f4e180c948db9ceebd1af2aaf7af
https://doi.org/10.1085/jgp.201611571
https://doi.org/10.1085/jgp.201611571
Autor:
Yasna Jaramillo, Edward D. Crandall, Gary E. Shull, Gaspar Peña-Münzenmayer, James E. Melvin, Sooji Choi, Per Flodby, Zea Borok, Frances Liu, Yusuke Kondo, Marcelo A. Catalán
Publikováno v:
Proceedings of the National Academy of Sciences. 112:2263-2268
Activation of an apical Ca(2+)-activated Cl(-) channel (CaCC) triggers the secretion of saliva. It was previously demonstrated that CaCC-mediated Cl(-) current and Cl(-) efflux are absent in the acinar cells of systemic Tmem16A (Tmem16A Cl(-) channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c8cc1e6f6b27925f4fabea28d49139
https://doi.org/10.1073/pnas.1415739112
https://doi.org/10.1073/pnas.1415739112
Autor:
Elías Vera-Sigüenza, James Sneyd, Gaspar Peña-Münzenmayer, James E. Melvin, Marcelo A. Catalán
Publikováno v:
Bulletin of mathematical biology. 80(2)
We develop a mathematical model of a salivary gland acinar cell with the objective of investigating the role of two [Formula: see text] exchangers from the solute carrier family 4 (Slc4), Ae2 (Slc4a2) and Ae4 (Slc4a9), in fluid secretion. Water trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027598c5980670e6fbde37ef210eb7ae
https://pubmed.ncbi.nlm.nih.gov/29209914
https://pubmed.ncbi.nlm.nih.gov/29209914
Publikováno v:
Cell Calcium. 55:362-368
In the last 15 years, remarkable progress has been realized in identifying the genes that encode the ion-transporting proteins involved in exocrine gland function, including salivary glands. Among these proteins, Ca(2+)-dependent K(+) channels take p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02b915abe009cdc26a0e043ced1fa090
https://doi.org/10.1016/j.ceca.2014.01.005
https://doi.org/10.1016/j.ceca.2014.01.005
Autor:
María Isabel Niemeyer, Carolina Añazco, Gaspar Peña-Münzenmayer, Francisco V. Sepúlveda, L. Pablo Cid, Carla Araya
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 465:1715-1726
TASK-2 (K2P5.1) is a background K(+) channel opened by extra- or intracellular alkalinisation that plays a role in renal bicarbonate handling, central chemoreception and cell volume regulation. Here, we present results that suggest that TASK-2 is als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ddd8a55f0725f55f09697f5f54fcf6c
https://doi.org/10.1007/s00424-013-1314-0
https://doi.org/10.1007/s00424-013-1314-0
Autor:
Sebastian Brauchi, Marcelo A. Catalán, Gaspar Peña-Münzenmayer, Fernanda Fernandez, Juan José Viveros, Lisandra Flores
Publikováno v:
Biophysical Journal. 114:330a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1b3145fd6be457a53750366ff616ee5
https://doi.org/10.1016/j.bpj.2017.11.1851
https://doi.org/10.1016/j.bpj.2017.11.1851
Autor:
Marcelo A. Catalán, Gary E. Shull, Yasna Jaramillo, Yusuke Kondo, James E. Melvin, Frances Liu, Gaspar Peña-Münzenmayer
Publikováno v:
The Journal of biological chemistry. 290(17)
Transcellular Cl(-) movement across acinar cells is the rate-limiting step for salivary gland fluid secretion. Basolateral Nkcc1 Na(+)-K(+)-2Cl(-) cotransporters play a critical role in fluid secretion by promoting the intracellular accumulation of C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019dcc5980b05d0bc132dfc8be1aac33
https://pubmed.ncbi.nlm.nih.gov/25745107
https://pubmed.ncbi.nlm.nih.gov/25745107
Autor:
Karen I, López-Cayuqueo, Gaspar, Peña-Münzenmayer, María Isabel, Niemeyer, Francisco V, Sepúlveda, L Pablo, Cid
Publikováno v:
Pflugers Archiv : European journal of physiology. 467(5)
TASK-2 (K2P5) was one of the earliest members of the K2P two-pore, four transmembrane domain K(+) channels to be identified. TASK-2 gating is controlled by changes in both extra- and intracellular pH through separate sensors: arginine 224 and lysine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04f43aa8efb819d08be8be1db85faba7
https://pubmed.ncbi.nlm.nih.gov/25315981
https://pubmed.ncbi.nlm.nih.gov/25315981
Publikováno v:
PFLUGERS ARCHIV
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
TASK-2 is a K2P K(+) channel considered as a candidate to mediate CO2 sensing in central chemosensory neurons in mouse. Neuroepithelial cells in zebrafish gills sense CO2 levels through an unidentified K2P K(+) channel. We have now obtained zfTASK-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0b72f8ecb43f9d3588b9d3cde04159