Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Gasnat Shaboodien"'
Autor:
Thomas Aldersley, John Lawrenson, Paul Human, Gasnat Shaboodien, Blanche Cupido, George Comitis, Rik De Decker, Barend Fourie, Lenise Swanson, Alexia Joachim, Phaphama Magadla, Malebogo Ngoepe, Liam Swanson, Alistair Revell, Raj Ramesar, Andre Brooks, Nicole Saacks, Bianca De Koning, Karen Sliwa, John Anthony, Ayesha Osman, Bernard Keavney, Liesl Zühlke
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Objectives: The PartneRships in cOngeniTal hEart disease (PROTEA) project aims to establish a densely phenotyped and genotyped Congenital Heart Disease (CHD) cohort for southern Africa. This will facilitate research into the epidemiology and genetic
Externí odkaz:
https://doaj.org/article/c394123826a944d6ba99bca53a1a2b65
Autor:
Tafadzwa, Machipisa, Chishala, Chishala, Gasnat, Shaboodien, Liesl J, Zühlke, Babu, Muhamed, Shahiemah, Pandie, Jantina de, Vries, Nakita, Laing, Alexia, Joachim, Rezeen, Daniels, Mpiko, Ntsekhe, Christopher T, Hugo-Hamman, Bernard, Gitura, Stephen, Ogendo, Peter, Lwabi, Emmy, Okello, Albertino, Damasceno, Celia, Novela, Ana O, Mocumbi, Geoffrey, Madeira, John, Musuku, Agnes, Mtaja, Ahmed, ElSayed, Huda H M, Alhassan, Fidelia, Bode-Thomas, Christopher, Yilgwan, Ganiyu, Amusa, Esin, Nkereuwem, Nicola, Mulder, Raj, Ramesar, Maia, Lesosky, Heather J, Cordell, Michael, Chong, Bernard, Keavney, Guillaume, Paré, Mark E, Engel, C, Durojaiye-Amodu
Publikováno v:
Circulation. Genomic and precision medicine.
Background: The genetics of rheumatic heart disease (RHDGen) Network was developed to assist the discovery and validation of genetic variations and biomarkers of risk for rheumatic heart disease (RHD) in continental Africans, as a part of the global
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f9e749147625c1e7a54be9be665f76
https://pubmed.ncbi.nlm.nih.gov/36548480
https://pubmed.ncbi.nlm.nih.gov/36548480
Autor:
Stephen Kamuli, Polycarp Ndibangwi, Ntobeko A B Ntusi, Gasnat Shaboodien, Timothy F Spracklen, Carla Van Niekerk
Publikováno v:
Cardiovasc Diagn Ther
In sub-Saharan Africa (SSA), the burden of noncommunicable diseases (NCDs) is rising disproportionately in comparison to the rest of the world, affecting urban, semi-urban and rural dwellers alike. NCDs are predicted to surpass infections like human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b6e6c401afa74c61b7fc1e64be14e9
https://doi.org/10.21037/cdt.2019.10.03
https://doi.org/10.21037/cdt.2019.10.03
Publikováno v:
American Journal of Medical Genetics Part C: Seminars in Medical Genetics. 184:159-177
Genetic association studies in rheumatic heart disease (RHD) have the potential to contribute toward our understanding of the pathogenetic mechanism, and may shed light on controversies about RHD etiology. Furthermore, genetic association studies may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5cc0e93db686667d8e4d400841c45c5
https://doi.org/10.1002/ajmg.c.31773
https://doi.org/10.1002/ajmg.c.31773
Publikováno v:
Heart (British Cardiac Society). 108(23)
Over the past three decades numerous disease-causing genes have been linked to the pathogenesis of heritable cardiomyopathies, but many causal genes are yet to be identified. Next-generation sequencing (NGS) platforms have revolutionised clinical tes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d349520eb47b9663f41f01af838e56b1
https://pubmed.ncbi.nlm.nih.gov/35140110
https://pubmed.ncbi.nlm.nih.gov/35140110
Autor:
Nicole Saacks, Bernard Keavney, James Eales, Gasnat Shaboodien, Liesl Zühlke, Timothy F Spracklen
Publikováno v:
SA Heart. 18
As the leading non-infectious cause of paediatric morbidity and mortality worldwide, congenital heart disease (CHD) is a significant social and healthcare burden, especially in low- and lower-middle-income countries, including South Africa. The aetio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4b879a57a2395c97c267d289e8e2a38
https://doi.org/10.24170/18-2-4886
https://doi.org/10.24170/18-2-4886
Autor:
Andre Brooks, George Comitis, Phaphama Magadla, Thomas Aldersley, Blanche Cupido, Raj Ramesar, Bernard Keavney, James Eales, John Anthony, Timothy F Spracklen, Bianca de Koning, Karen Sliwa, Ayesha Osman, Liesl Zühlke, Alistair Revell, Paul Human, Lenise Swanson, Rik De Decker, Nicole Saacks, Alexia Joachim, Barend Fourie, John Lawrenson, Malebogo Ngoepe, Gasnat Shaboodien, Liam Swanson
Publikováno v:
Basic science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfcfb2096e00e3e6d40ba57780d764a6
https://doi.org/10.1136/heartjnl-2021-bcs.224
https://doi.org/10.1136/heartjnl-2021-bcs.224
Autor:
Tarryn L. Botha, Sarah Kraus, Nakita Laing, Stephen Kamuli, Zandile Booi, Ashley Chin, Timothy F Spracklen, Paul R. Kasher, Gasnat Shaboodien, Bernard Keavney, Donna J. Page, Ntobeko A B Ntusi
Publikováno v:
Circulation: Genomic and Precision Medicine. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc1977ea0dd91b913caaa9c13f3c337a
https://doi.org/10.1161/circgen.120.003138
https://doi.org/10.1161/circgen.120.003138
Autor:
Sarah M. Kraus, Gasnat Shaboodien, Veronica Francis, Nakita Laing, Jacqui Cirota, Ashley Chin, Shahiemah Pandie, John Lawrenson, George A.M. Comitis, Barend Fourie, Liesl Zühlke, Ambroise Wonkam, Helen Wainwright, Albertino Damasceno, Ana Olga Mocumbi, Lungile Pepeta, Khulile Moeketsi, Baby M. Thomas, Kandathil Thomas, Makoali Makotoko, Stephen Brown, Mpiko Ntsekhe, Karen Sliwa, Motasim Badri, Freedom Gumedze, Heather J. Cordell, Bernard Keavney, Vanessa Ferreira, Masliza Mahmod, Leslie T. Cooper, Magdi Yacoub, Stefan Neubauer, Hugh Watkins, Bongani M. Mayosi, Ntobeko A.B. Ntusi, Julius Mwita, Ahmed El-Guindy, Sir Magdi Yacoub, Tolno Sandy Kola, F. Ayub Barasa, Okechukwu Ogah, James Russell, Sarah Kraus, Bongani Mayosi, Ntobeko Ntusi, Shaheen Pandie, Blanche Cupido, George Comitis, Rik De Decker, Paul Brink, Marshall Heradien, Nomlindo Makubalo, Mahlubandile Nxele, Benjamin Longo-Mbenza, Baby Thomas, Kandithalal Thomas, Ahmed Suliman, Sulafa Ali, Kemilembe Tibazarwa, Charles Mondo, Michael Mungoma, Heather Cordell, Ellise Tapiwa Gambahaya
Publikováno v:
International journal of cardiology. 333
Background Heart failure (HF), the dominant form of cardiovascular disease in Africans, is mainly due to hypertension, rheumatic heart disease and cardiomyopathy. Cardiomyopathies pose a great challenge because of poor prognosis and high prevalence i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da6ed6491aa537129db31931f66b3ac
https://pubmed.ncbi.nlm.nih.gov/33607192
https://pubmed.ncbi.nlm.nih.gov/33607192
Autor:
Gaurang Deshpande, Bridget Hodkinson, Asgar Ali Kalla, Gasnat Shaboodien, T. F. Spracklen, Ayanda Gcelu, Mohammed Tikly, Bongani M. Mayosi
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-4 (2018)
Scientific Reports
Scientific Reports
Systemic sclerosis (SSc) is a prototypic systemic fibrotic disease with unclearly characterized genetic basis. We have discovered that mutations in family with sequence similarity 111, member B (FAM111B) gene cause hereditary fibrosing poikiloderma w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653d9703665b653721e26301d1905ed1
http://link.springer.com/article/10.1038/s41598-018-34341-7
http://link.springer.com/article/10.1038/s41598-018-34341-7