Zobrazeno 1 - 10
of 2 559
pro vyhledávání: '"Gasdermin D"'
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 8241-8259 (2024)
Xiaoxi Fan,1,2,* Wenli Zhang,2,3,* Ruihan Zheng,1 Yucong Zhang,1 Xianhui Lai,4 Jibo Han,5 Zimin Fang,1 Bingjiang Han,5 Weijian Huang,1 Bozhi Ye,1,2 Shanshan Dai1,6 1The Key Laboratory of Cardiovascular Disease of Wenzhou, Department of Cardio
Externí odkaz:
https://doaj.org/article/8fd829b22812414eacc68fd29063619a
Autor:
Fatma Karasabanoglu, Beyza Arpacı Saylar, Busra Seker Atas, Merve Topaktas Ozbas, Filiz Yarsilikal Guleroglu, Ali Cetin
Publikováno v:
Haseki Tıp Bülteni, Vol 62, Iss 3, Pp 128-135 (2024)
Aim: Gasdermin-D (GSDMD) and pannexin-1 (PANX1), which are proinflammatory proteins, may be involved in the pathogenesis of complications in pregnant women with obesity. We aimed to investigate the expression of GSDMD and PANX1 biochemically in sampl
Externí odkaz:
https://doaj.org/article/a0b420cba5d5499b8e7212934f9d815b
Autor:
Jiani Shen, Feng Li, Xu Han, Dongying Fu, Yiping Xu, Changjian Zhu, Zhou Liang, Ziwen Tang, Ruilin Zheng, Xinrong Hu, Ruoni Lin, Qiaoqiao Pei, Jing Nie, Ning Luo, Xiaoyan Li, Wei Chen, Haiping Mao, Yi Zhou, Xueqing Yu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Gasdermin D (GSDMD) is emerging as an important player in autoimmune diseases, but its exact role in lupus nephritis (LN) remains controversial. Here, we identified markedly elevated GSDMD in human and mouse LN kidneys, predominantly in CD11
Externí odkaz:
https://doaj.org/article/a604bdbced2a4e44a0dcd823c3e28a16
Autor:
XiaPing Zhang, Bo Yang
Publikováno v:
Renal Failure, Vol 46, Iss 1 (2024)
Objective This study aimed to explore the serum levels of gasdermin D (GSDMD) in uremic (end-stage kidney disease, ESKD) patients and their correlation with vascular calcification (VC) and clinical results.Methods This prospective observational cohor
Externí odkaz:
https://doaj.org/article/ba58ce28ae85481d874b8fd124803b72
Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Inflammatory diseases compromise a clinically common and diverse group of conditions, causing detrimental effects on body functions. Gasdermins (GSDM) are pore-forming proteins, playing pivotal roles in modulating inflammation. Belonging to the GSDM
Externí odkaz:
https://doaj.org/article/17dffbc30dc648d391c0610eac2c110b
Autor:
Bart Boersma, Viola Puddinu, Arnaud Huard, Sébastien Fauteux-Daniel, Pratyaksha Wirapati, Sofia Guedri, Jean-Christophe Tille, Thomas McKee, Mikael Pittet, Gaby Palmer, Carole Bourquin
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Inflammation plays a pivotal role in cancer development, with chronic inflammation promoting tumor progression and treatment resistance, whereas acute inflammatory responses contribute to protective anti-tumor immunity. Gasdermin D (GSDMD) mediates t
Externí odkaz:
https://doaj.org/article/f4b80242743a430885ba5c660f5b5289
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectiveThis study aimed to evaluate the role of absent in melanoma 2 (AIM2) inflammasome-mediated pyroptosis in the pathogenesis of acute gouty arthritis (AGA) and asymptomatic hyperuricemia(AHU).MethodsA cohort of 30 AGA patients, 30 AHU individua
Externí odkaz:
https://doaj.org/article/afde4ee3af184f0d9238c445e842676a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Non-alcoholic fatty liver disease (NAFLD) is a clinical pathological syndrome characterized by the excessive accumulation of fat within liver cells, which can progress to end-stage liver disease in severe cases, posing a threat to life. Pyroptosis is
Externí odkaz:
https://doaj.org/article/32edef78e3de4650afa1b3f735a825ec