Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Gary Weisinger"'
Autor:
Esther Osher, Yossi Anis, Ruth Singer-Shapiro, Nataly Urshanski, Tamar Unger, Shira Albeck, Oren Bogin, Gary Weisinger, Fortune Kohen, Avi Valevski, Aviva Fattal-Valevski, Liora Sagi, Michal Weitman, Yulia Shenberger, Nadav Sagiv, Ruth Navon, Meir Wilchek, Naftali Stern
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101300- (2024)
Tay-Sachs (TS) disease is a neurodegenerative disease resulting from mutations in the gene encoding the α-subunit (HEXA) of lysosomal β-hexosaminidase A (HexA). We report that (1) recombinant HEXA alone increased HexA activity and decreased GM2 con
Externí odkaz:
https://doaj.org/article/b46b268575554f2eb291b7d475a23c94
Publikováno v:
Cell Transplantation, Vol 2 (1993)
Combining genetic engineering and cell transplantation has been proposed as one way to overcome the limited availability of donor tissue that may restrict the application of graft therapy to neurological diseases. Important issues in this approach co
Externí odkaz:
https://doaj.org/article/20a31fbd2bd44fbdb57aaa1b7b5021a5
Autor:
Rona Limor, Gary Weisinger, Marielle Kaplan, Naftali Stern, Esther Knoll, Michal Naidich, Orly Sharon, Shlomo Keidar
Publikováno v:
Journal of Cellular Biochemistry. 108:1203-1210
Several lines of evidence suggest that aldosterone excess may have detrimental effects in the cardiovascular system, independent of its interaction with the renal epithelial cells. Here we examined the possibility that aldosterone modulates 12- and/o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d7dfeb0a9ea816899dee6620a52d45
https://doi.org/10.1002/jcb.22352
https://doi.org/10.1002/jcb.22352
Publikováno v:
American Journal of Hypertension. 21:219-223
Background Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) is a member of the nuclear receptor family that has been implicated in cell differentiation and proliferation, glucose metabolism, macrophage development, and inflammatory respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3a7b278cf2f72ba638202a1b7318de
https://doi.org/10.1038/ajh.2007.39
https://doi.org/10.1038/ajh.2007.39
Autor:
Yonit Marcus-Perlman, Rona Limor, Naftali Stern, Fortune Kohen, Michael Firer, Gary Weisinger, Esther Knoll, Vera Schinder
Publikováno v:
Biochemical and Biophysical Research Communications. 356:554-560
The current study sets out to characterize the intracellular localization of the platelet-type 12S-lipoxygenase (12-LO), an enzyme involved in angiotensin-II induced signaling in vascular smooth muscle cells (VSMC). Immunohistochemical analysis of VS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16eab776e571bd65f5f8672ed574b3a3
https://doi.org/10.1016/j.bbrc.2007.03.012
https://doi.org/10.1016/j.bbrc.2007.03.012
Publikováno v:
Molecular and Cellular Endocrinology. 252:201-206
Activation of the 5 lipoygenase (5LO) system within the vascular bed requires the presence of several cell types with distinct transcellular cross-talk mechanisms, resulting in the generation of 5LO produced metabolites and increased expression of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81cf8ee811d0121244f79a4ae525aee7
https://doi.org/10.1016/j.mce.2006.03.038
https://doi.org/10.1016/j.mce.2006.03.038
Autor:
Gavril W. Pasternak, Moshe Gavish, Solomon H. Snyder, Abraham Weizman, Evgeny Levin, Leo Veenman, Arumugam Premkumar, Wilfried Kugler, Max Lakomek, Ilana Spanier, Svetlana Leschiner, Gary Weisinger
Publikováno v:
Biochemistry. 44:9924-9935
Peripheral-type benzodiazepine receptors (PBR) are constituted by three protein components, the isoquinoline binding protein (IBP), the voltage-dependent anion channel (VDAC), and the adenine nucleotide transporter (ANT). Recently, we found that high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155d62574297fb87f4674fd16b87c00d
https://doi.org/10.1021/bi050150s
https://doi.org/10.1021/bi050150s
Autor:
Moshe Gavish, Svetlana Leschiner, Ilana Spanier, Gary Weisinger, Leo Veenman, Ela Kelly-Hershkovitz
Publikováno v:
Biochemistry. 43:12315-12321
Peripheral benzodiazepine receptors (PBR), first described more than 20 years ago, have been attributed with many putative functions including ones in cellular proliferation and cellular respiration. Hence, it is quite conceivable that deregulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798f5553fde8697cb26d0374652ee2e4
https://doi.org/10.1021/bi030251v
https://doi.org/10.1021/bi030251v
Autor:
Moshe Gavish, Abraham Weizman, Gary Weisinger, Hans Scherübl, Joseph Yanai, N. Eckstein, Rona Limor, Idit Golani, Ilana Spanier, Svetlana Leschiner, Kerstin Maaser
Publikováno v:
Biochemistry. 40:10213-10222
The peripheral benzodiazepine receptor (PBR) is composed of three subunits with molecular masses of 18, 30, and 32 kDa. Many physiological functions have been attributed to the PBR, including regulation of steroidogenesis. Furthermore, the PBR itself
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23e81187546060a23500d8f7f1497c2
https://doi.org/10.1021/bi010431+
https://doi.org/10.1021/bi010431+
Autor:
A P Kozikowski, Abraham Weizman, Hans Scherübl, Kerstin Maaser, A. Jansen, Martin Zeitz, Pierre Carayon, Ernst-Otto Riecken, Moshe Gavish, Michael Höpfner, Gary Weisinger
Publikováno v:
British Journal of Cancer
The peripheral benzodiazepine receptor (PBR) has been implicated in growth control of various tumour models. Although colorectal cancers were found to overexpress PBR, the functional role of PBR in colorectal cancer growth has not been addressed to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f8f57d94dc90d17fa42108d4435bb0
http://europepmc.org/articles/PMC2363981
http://europepmc.org/articles/PMC2363981