Genome-wide Methyl-Seq analysis of blood-brain targets of glucocorticoid exposure

Autor: Fayaz Seifuddin, Gary Wand, Olivia Cox, Mehdi Pirooznia, Laura Moody, Xiaoju Yang, Jonathan Tai, Gretha Boersma, Kellie Tamashiro, Peter Zandi, Richard Lee

Publikováno v: Epigenetics, Vol 12, Iss 8, Pp 637-652 (2017)

Chronic exposure to glucocorticoids (GCs) can lead to psychiatric complications through epigenetic mechanisms such as DNA methylation (DNAm). We sought to determine whether epigenetic changes in a peripheral tissue can serve as a surrogate for those

Externí odkaz: https://doaj.org/article/a11c189eacb548589acbbf7149ccf216

Single nucleotide polymorphism rs17849071 G/T in the PIK3CA gene is inversely associated with follicular thyroid cancer and PIK3CA amplification.

Autor: Jeffrey C Xing, Ralph P Tufano, Avaniyapuram Kannan Murugan, Dingxie Liu, Gary Wand, Paul W Ladenson, Mingzhao Xing, Barry Trink

Publikováno v: PLoS ONE, Vol 7, Iss 11, p e49192 (2012)

The proto-oncogene PIK3CA has been well studied for its activating mutations and genomic amplifications but not single nucleotide polymorphism (SNP) in thyroid cancer. We investigated SNP rs17849071 (minor allele G and major allele T) in PIK3CA in th

Externí odkaz: https://doaj.org/article/218b82739f21463894d12be1fe8add86

No allelic association of an exon 13 polymorphism of the Gsα gene to alcohol and/or drug dependence

Autor: Henry R. Kranzler, Mary E. McCaul, Joel Gelernter, Gary Wand

Publikováno v: Addiction Biology. 2:309-316

The adenylyl cyclase signal transduction system, a ubiquitous second messenger system, has been identified as a potential marker for genetic risk of alcohol and drug dependence. Using the polymerase chain reaction (PCR) to amplify exon 13 of the Gsα

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac9b864f110144af3d69def81ca970d
https://doi.org/10.1080/13556219772606

Stress and the HPA axis: role of glucocorticoids in alcohol dependence

Autor: Mary Ann C, Stephens, Gary, Wand

Publikováno v: Alcohol Research : Current Reviews

Stress has long been suggested to be an important correlate of uncontrolled drinking and relapse. An important hormonal response system to stress—the hypothalamic–pituitary–adrenal (HPA) axis—may be involved in this process, particularly stre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::66105de0a368d5411ed004b905d6017b
https://pubmed.ncbi.nlm.nih.gov/23584113

Contributors

Autor: Lloyd Paul Aiello, Erik K. Alexander, Carolyn A. Allan, Bruno Allolio, Peter Angelos, Sree Appu, Richard J. Auchus, Joseph Avruch, Lloyd Axelrod, Rebecca S. Bahn, H.W.G. Baker, Randall B. Barnes, Murat Bastepe, John D. Baxter, Paolo Beck-Peccoz, Graeme I. Bell, John P. Bilezikian, Stephen R. Bloom, Manfred Blum, Steen J. Bonnema, Diego Botero, Roger Bouillon, Andrew J.M. Boulton, Glenn D. Braunstein, F. Richard Bringhurst, Frank J. Broekmans, Marcello D. Bronstein, Edward M. Brown, Chuong Bui, Col. Henry B. Burch, Henry G. Burger, Richard O. Burney, John B. Buse, Peter C. Butler, Paolo Cappabianca, Maria Luiza Avancini Caramori, Robert M. Carey, Esther Carlton, David Carmody, Jose F. Caro, Francesco Cavagnini, Jerry Cavallerano, Luigi M. Cavallo, Shu Jin Chan, R. Jeffrey Chang, Roland D. Chapurlat, V. Krishna Chatterjee, Luca Chiovato, Kyung J. Cho, Daniel Christophe, Teng-Teng Chung, John A. Cidlowski, Adrian J.L. Clark, Peter E. Clark, David R. Clemmons, Robert V. Considine, Georges Copinschi, Kyle D. Copps, C. Hamish Courtney, Leona Cuttler, Melita L. Daley, Mehul Dattani, Stephen N. Davis, Oreste de Divitiis, Mario De Felice, Ralph A. DeFronzo, Leslie J. De Groot, David de Kretser, Ahmed J. Delli, Pierre D. Delmas, Marie B. Demay, Paul Devroey, Roberto Di Lauro, Sean F. Dinneen, Jacques E. Dumont, Kathleen M. Dungan, Daniel J. Drucker, Michael J. Econs, David A. Ehrmann, Graeme Eisenhofer, Gregory F. Erickson, Barbro Eriksson, Eric Espiner, Felice Esposito, Victoria Esser, Erica A. Eugster, Sadaf Farooqi, Martin Fassnacht, Bart C.J.M. Fauser, Gianfranco Fenzi, Ele Ferrannini, David M. Findlay, Courtney Finlayson, Delbert A. Fisher, Maguelone G. Forest, Daniel W. Foster, Mason Wright Freeman, Mark Frydenberg, Peter Fuller, Robert F. Gagel, Jason L. Gaglia, Gianluigi Galizia, Chuanyun Gao, Thomas J. Gardella, Bruce D. Gaylinn, Harry K. Genant, Michael S. German, Mohammad A. Ghatei, Linda C. Giudice, Anna Glasier, Francis H. Glorieux, Javier González-Maeso, Louis J. Gooren, David F. Gordon, Karen A. Gregerson, Milton D. Gross, Ashley Grossman, Valéria C. Guimarães, Mark Gurnell, Nadine Haddad, Daniel J. Haisenleder, David J. Handelsman, John B. Hanks, Mark John Hannon, Simon W. Hayward, Matthias Hebrok, Laszlo Hegedüs, Georg Hennemann, Maria K. Herndon, Peter Hindmarsh, Ken K.Y. Ho, Nelson D. Horseman, Mara J. Horwitz, Mimi Hu, Ieuan A. Hughes, Christopher J. Hupfeld, Hero K. Hussain, Peter Illingworth, J. Larry Jameson, Nathalie Josso, Harald Jüppner, Jeffrey Kalish, Edwin L. Kaplan, Jeffrey B. Kerr, Ronald Klein, Meyer Knobel, Efstratios Kolibianakis, John J. Kopchick, Peter Kopp, Márta Korbonits, Melvyn Korobkin, Stephen M. Krane, Knut Krohn, Henry M. Kronenberg, John M. Kyriakis, Sue Lynn Lau, John H. Lazarus, Diana L. Learoyd, Harold E. Lebovitz, Paul Lee, Åke Lernmark, Laura J. Lewis-Tuffin, Zhi-Liang Lu, Paolo Emidio Macchia, Noel K. Maclaren, Carine Maenhaut, Christa Maes, Katharina M. Main, Carl D. Malchoff, Diana Mark Malchoff, Rayaz A. Malik, Susan J. Mandel, Christos Mantzoros, Eleftheria Maratos-Flier, Stefania Marchisotta, Michele Marinò, John C. Marshall, Thomas F.J. Martin, T. John Martin, Gabriel Á. Martos-Moreno, Christopher J. Mathias, Michael Mauer, Elizabeth A. McGee, Neil J. McKenna, Robert I. McLachlan, Geraldo Medeiros-Neto, Juris J. Meier, Shlomo Melmed, Boyd E. Metzger, Robert Millar, Walter L. Miller, Madhusmita Misra, Mark E. Molitch, David D. Moore, Damian G. Morris, Allan U. Munck, Jon Nakamoto, Anikó Náray-Fejes-Tóth, Ralf Nass, David M. Nathan, Maria I. New, Carolyn Nguyen, Lynnette K. Nieman, John H. Nilson, Jeffrey A. Norton, Robert H. Oakley, Kjell Öberg, Jerrold M. Olefsky, Stephen O’Rahilly, Umut Ozcan, Karel Pacak, Furio Pacini, Shetal H. Padia, Ralf Paschke, Adam Pawson, Alison C. Peck, Francesca Pecori Giraldi, Luca Persani, Richard L. Phelps, Louis H. Philipson, Kevin Phillips, Aldo Pinchera, Frank B. Pomposelli, John T. Potts, Charmian A. Quigley, Marcus Quinkler, Christine Campion Quirk, Miriam T. Rademaker, Ewa Rajpert-De Meyts, Eric Ravussin, David W. Ray, Nancy King Reame, Samuel Refetoff, Ravi Retnakaran, Rodolfo A. Rey, Christopher J. Rhodes, E. Chester Ridgway, Gail P. Risbridger, Robert A. Rizza, Bruce Robinson, Pierre P. Roger, Michael G. Rosenfeld, Robert L. Rosenfield, James H. Rosing, Peter Rossing, Robert T. Rubin, Neil Ruderman, Irma H. Russo, Jose Russo, Wael Antoine Salameh, Isidoro B. Salusky, Mary H. Samuels, Richard J. Santen, Nanette Santoro, Virginia D. Sarapura, Stuart C. Sealfon, Patrick M. Sexton, Gerald I. Shulman, Paolo S. Silva, Shonni J. Silverberg, Frederick R. Singer, Niels E. Skakkebaek, Dorota Skowronska-Krawczyk, Carolyn L. Smith, Philip W. Smith, Roger Smith, Steven R. Smith, Peter J. Snyder, Richard Stanhope, René St-Arnaud, Donald F. Steiner, Adam Stevens, Andrew F. Stewart, Paul M. Stewart, Donald L. St. Germain, Jim Stockigt, Jerome F. Strauss, Lillian Marie Swiersz, Lyndal J. Tacon, Shahrad Taheri, Rajesh V. Thakker, Chris Thompson, Michael O. Thorner, Henri J.L.M. Timmers, Jorma Toppari, Cristina Traggiai, Michael L. Traub, Yolanda Tseng, Fred W. Turek, Eve Van Cauter, Greet Van den Berghe, André C. Van Steirteghem, Gilbert Vassart, Eric Vilain, Theo J. Visser, Michael P. Wajnrajch, Gary Wand, Paul Webb, Anthony P. Weetman, Nancy L. Weigel, Gordon C. Weir, Roy E. Weiss, Katherine Wesseling-Perry, Anne White, Kenneth E. White, Morris F. White, Michael P. Whyte, Wilmar M. Wiersinga, Joseph I. Wolfsdorf, Bernard Zinman

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9bb0969ef3a1b0777dd9cfe46cc319b0
https://doi.org/10.1016/b978-1-4160-5583-9.00158-1