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Autor:
Gary W. Morrow
Building on the foundation of a one-year introductory course in organic chemistry, Bioorganic Synthesis: An Introduction focuses on organic reactions involved in the biosynthesis of naturally-occurring organic compounds with special emphasis on natur
Autor:
Gary W. Morrow
Publikováno v:
Comprehensive Heterocyclic Chemistry IV ISBN: 9780128186565
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab72104118ee931dbdec459e9b267e4a
https://doi.org/10.1016/b978-0-12-818655-8.00035-4
https://doi.org/10.1016/b978-0-12-818655-8.00035-4
Publikováno v:
Synthetic Communications. 43:1676-1682
Mitsunobu coupling of 3-hydroxymethylbenzofurans with o-iodophenols affords 3-(2-iodophenoxy)methylbenzofurans which under go a useful 6-endo Heck cyclization under Jeffery conditions to afford pterocarpene-type heterocycles. The unsubstituted parent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f6ebce503078574431c3c22898a9126
https://doi.org/10.1080/00397911.2012.661910
https://doi.org/10.1080/00397911.2012.661910
Autor:
Gary W. Morrow
Publikováno v:
Bioorganic Synthesis
We have already seen that some of the basic building blocks used in the biosynthesis of natural products are amino acids such as phenylalanine, tyrosine, and others. These and other crucial construction materials such as the acyl group in acetyl-CoA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93e2d171cee309e28e6a0811bcad8783
https://doi.org/10.1093/oso/9780199860531.003.0006
https://doi.org/10.1093/oso/9780199860531.003.0006
Autor:
Gary W. Morrow
Publikováno v:
Bioorganic Synthesis
Though definitions may vary from source to source, the term alkaloid generally refers to members of a large set of naturally occurring, slightly basic (i.e., alkaline) nitrogen-containing organic compounds. Generally excluded from this group are amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3cfc5938d1e12ba447a83386cc1d1de
https://doi.org/10.1093/oso/9780199860531.003.0010
https://doi.org/10.1093/oso/9780199860531.003.0010
Autor:
Gary W. Morrow
Publikováno v:
Bioorganic Synthesis
Like other amino acids, the aromatic amino acids phenylalanine, tyrosine, and tryptophan are vitally important for protein synthesis in all organisms. However, while animals can synthesize tyrosine via oxidation of phenylalanine, they can synthesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63a4f5a41f9573805453f1a27b617c9c
https://doi.org/10.1093/oso/9780199860531.003.0009
https://doi.org/10.1093/oso/9780199860531.003.0009
Autor:
Gary W. Morrow
Publikováno v:
Bioorganic Synthesis
We saw in the previous chapter how Otto Wallach’s early proposal regarding the structural origin of terpenoid natural products was later refined by the insightful work of Leopold Rudzicka, leading to the biogenetic isoprene rule and all that it imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d50c177e7a28a18ae43d21cfa47450f0
https://doi.org/10.1093/oso/9780199860531.003.0008
https://doi.org/10.1093/oso/9780199860531.003.0008
Autor:
Gary W. Morrow
Publikováno v:
Bioorganic Synthesis
The German chemist Friedrich Wöhler is generally credited with the first laboratory synthesis of a known organic compound (urea) from inorganic materials. He accomplished this by the simple heating of an inorganic salt, ammonium cyanate (NH4OCN).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b04cc9da681e45de5088e82bd9456b9
https://doi.org/10.1093/oso/9780199860531.003.0011
https://doi.org/10.1093/oso/9780199860531.003.0011
Autor:
Gary W. Morrow
Publikováno v:
Bioorganic Synthesis
It was Otto Wallach (1847– 1931) who first coined the term “terpene” and made the observation that many plant-derived essential oils had chemical structures whose composition was based on multiples of a basic five-carbon unit. His work with tur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c57530835e42f2168031f263b915b396
https://doi.org/10.1093/oso/9780199860531.003.0007
https://doi.org/10.1093/oso/9780199860531.003.0007
Autor:
Gary W. Morrow
It is not essential to have a background in enzymology or biochemistry to gain at least an introductory-level understanding of many biosynthetic processes, so this book does not deal with enzymology or enzyme structure or function in any significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd14bd1bae69aea023dfd1f997ad8c98
https://doi.org/10.1093/oso/9780199860531.003.0005
https://doi.org/10.1093/oso/9780199860531.003.0005