Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Gary W. Harding"'
Publikováno v:
Hearing Research. 344:158-169
From our permanent collection of plastic-embedded flat preparations of chinchilla cochleae, 22 controls and 199 ears from noise-exposed animals were used to determine when, postexposure, hair cell (HC) and supporting cell (SC) degeneration were compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1b37f16b4e7970c84a4a3542d61fec
https://doi.org/10.1016/j.heares.2016.11.009
https://doi.org/10.1016/j.heares.2016.11.009
Autor:
Barbara A. Bohne, Gary W. Harding
Publikováno v:
Hearing Research. 254:54-63
In a previous study, we examined the relation between total energy in a noise exposure and the percentage losses of outer (OHC) and inner (IHC) hair cells in the basal and apical halves of 607 chinchilla cochleae [Harding, G.W., Bohne, B.A., 2004a. N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36495d086454002352922ad64e9a80d0
https://doi.org/10.1016/j.heares.2009.04.011
https://doi.org/10.1016/j.heares.2009.04.011
Autor:
Gary W. Harding, Barbara A. Bohne, William M. Landau, Kai Sun, Diego Torres-Russotto, P. M. Sinatra
Publikováno v:
Neurology. 72:1595-1600
Determination of auditory function is a fundamental part of a complete neurologic examination. Disability from permanent hearing loss is common in the general population. Current bedside auditory tests are unreliable and cumbersome. We evaluated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a2cbec585ada8a94a8e42d61348a0b
https://doi.org/10.1212/wnl.0b013e3181a41280
https://doi.org/10.1212/wnl.0b013e3181a41280
Publikováno v:
The Open Otorhinolaryngology Journal. 2:29-43
Objective: To determine what death pathways are followed by noise-damaged outer hair cells (OHCs). Methods: Chinchillas were exposed to a 0.5-kHz octave band of noise for 24 h. Administration of trypan blue in vivo was used to stain nuclei in cells w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa7e0238085d51aa1d6e68fcbcb9ace5
https://doi.org/10.2174/1874428100802010029
https://doi.org/10.2174/1874428100802010029
Publikováno v:
Hearing Research. 225:128-138
Infrasound (i.e.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc17bd1a0c3bee7dc6e937fac146100
https://doi.org/10.1016/j.heares.2007.01.016
https://doi.org/10.1016/j.heares.2007.01.016
Publikováno v:
Hearing Research. 204:90-100
Inbred C57BL/6J mice carry two copies of an age-related hearing loss gene (Ahl). It has been shown that these mice begin losing high-frequency hearing at two months. Several functional studies have reported that the Ahl gene renders mice more suscept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29e09861a5aa29be0a12a0fb2edea4d
https://doi.org/10.1016/j.heares.2005.01.004
https://doi.org/10.1016/j.heares.2005.01.004
Publikováno v:
Hearing Research. 175:82-100
An in vivo tracer was used to determine if the reticular lamina and/or the cell membranes abutting the endolymphatic space are temporarily disrupted after intense noise exposure (4-kHz OBN, 108-dB SPL, 1.75 h). Using a double-barreled micropipette, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e4171a5d4d18ee0c2a2ed9023457b4
https://doi.org/10.1016/s0378-5955(02)00713-x
https://doi.org/10.1016/s0378-5955(02)00713-x
Publikováno v:
Hearing Research. 145:123-129
An anatomically based frequency-place map was created for the mouse using C57BL/CBA F1 hybrids by matching noise-induced lesions in the organ of Corti with permanent hearing losses as determined by auditory brainstem response (ABR) thresholds. Twenty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9662e54be6b869594812ea806dbf3c5f
https://doi.org/10.1016/s0378-5955(00)00082-4
https://doi.org/10.1016/s0378-5955(00)00082-4
Publikováno v:
Hearing Research. 124:132-145
Eleven chinchillas between 1 and 2.4 years of age had the malleus/incus complex removed from one middle ear and then lived in the Washington University animal facilities for 4 years post-surgery. Each animal had one ear (termed ambient-noise) in whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5596f23c5a6d50eb1c0cb4ad18f8ee8a
https://doi.org/10.1016/s0378-5955(98)00132-4
https://doi.org/10.1016/s0378-5955(98)00132-4
Autor:
Gary W. Harding, Barbara A. Bohne
Publikováno v:
Hearing Research. 109:34-45
A technique has been developed for preparing the mouse temporal bone for histopathological examination: first, as a whole mount to detect any gross malformations of the bony or membranous labyrinths; second, in dissected segments to localize damage i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407f81857453d7749a36fff933c7d2f7
https://doi.org/10.1016/s0378-5955(97)00019-1
https://doi.org/10.1016/s0378-5955(97)00019-1