Zobrazeno 1 - 10
of 4 277
pro vyhledávání: '"Gary V"'
Autor:
Xiaojia Guo, Valerie Blanc, Nicholas O. Davidson, Heino Velazquez, Tian-min Chen, Dennis G. Moledina, Gilbert W. Moeckel, Robert L. Safirstein, Gary V. Desir
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Cisplatin (CP) induces acute kidney injury (AKI) whereby proximal tubules undergo regulated necrosis. Repair is almost complete after a single dose. We now demonstrate a role for Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
Externí odkaz:
https://doaj.org/article/cbd6c09daa0349ee9f062655e85219b0
Autor:
Georgia Charkoftaki, Reza Aalizadeh, Alvaro Santos-Neto, Wan Ying Tan, Emily A. Davidson, Varvara Nikolopoulou, Yewei Wang, Brian Thompson, Tristan Furnary, Ying Chen, Elsio A. Wunder, Andreas Coppi, Wade Schulz, Akiko Iwasaki, Richard W. Pierce, Charles S. Dela Cruz, Gary V. Desir, Naftali Kaminski, Shelli Farhadian, Kirill Veselkov, Rupak Datta, Melissa Campbell, Nikolaos S. Thomaidis, Albert I. Ko, Yale IMPACT Study Team, David C. Thompson, Vasilis Vasiliou
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-17 (2023)
Abstract Over the last century, outbreaks and pandemics have occurred with disturbing regularity, necessitating advance preparation and large-scale, coordinated response. Here, we developed a machine learning predictive model of disease severity and
Externí odkaz:
https://doaj.org/article/2f4a257343224b1581834ef8402d7d6e
Autor:
Marcelo V. Negrao, MD, Vassiliki A. Papadimitrakopoulou, MD, Andrew C. Price, MD, PhD, Alda L. Tam, MD, MBA, Muhammad Furqan, MD, Sandeep T. Laroia, MD, Erminia Massarelli, MS, MD, PhD, Jose Pacheco, MD, John V. Heymach, MD, PhD, Anne S. Tsao, MD, Gary V. Walker, MD, Lalit Vora, MD, David Mauro, MD, PhD, Heather Kelley, MA, James E. Wooldridge, MD, Arthur M. Krieg, MD, Jiaxin Niu, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 3, Pp 100423- (2023)
Introduction: Vidutolimod, a CpG-A TLR9 agonist, was investigated in a phase 1b study (CMP-001-003; ClinicalTrials.gov, NCT03438318) in combination with atezolizumab with and without radiation therapy (RT) in patients with advanced NSCLC. Methods: Pa
Externí odkaz:
https://doaj.org/article/375520c714da4dd0a0459208063f6fc7
Autor:
Andrew D. Richardson, Gary V. Kong, Katrina M. Taylor, James M. Le Moine, Matthew A. Bowker, Jarrett J. Barber, David Basler, Mariah S. Carbone, Michaela Hayer, George W. Koch, Mark R. Salvatore, A. Wesley Sonnemaker, David E. Trilling
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Biological soil crusts (biocrusts) are critical components of dryland and other ecosystems worldwide, and are increasingly recognized as novel model ecosystems from which more general principles of ecology can be elucidated. Biocrusts are often diver
Externí odkaz:
https://doaj.org/article/261fadb45459407cb58deb2a545311de
Autor:
Siu-Fun Wong, Joseph M. Unger, James L. Wade, Lynne I. Wagner, Mario E. Lacouture, Keisha C. Humphries, Anna Moseley, Kathryn Arnold, Mario R. Velasco, Justin D. Floyd, Benjamin T. Esparaz, Afsaneh Barzi, Heinz-Josef Lenz, Marianna Koczywas, Shaker Dakhil, Gary V. Burton, Michael J. Fisch, N. Lynn Henry, Dawn L. Hershman, Carol M. Moinpour
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 4, Iss 1, Pp 1-12 (2020)
Abstract Background Papulopustular rash is a common class effect of epidermal growth factor receptor inhibitors (EGFRI) that can affect patients’ health-related quality of life and cause disruptions to treatment. SWOG S1013 (NCT01416688) is a multi
Externí odkaz:
https://doaj.org/article/cc8f4d5ab8574139b368be4cd9f29553
Autor:
Yang Wang, Chen Chen, Gui-Lin Hu, Chao Chu, Xiao-Yu Zhang, Ming-Fei Du, Ting Zou, Qing Zhou, Yue-Yuan Liao, Qiong Ma, Ke-Ke Wang, Yue Sun, Dan Wang, Yu Yan, Yan Li, Hao Jia, Ze-Jiaxin Niu, Xi Zhang, Lan Wang, Zi-Yue Man, Wei-Hua Gao, Chun-Hua Li, Jie Zhang, Ke Gao, Hui-Xian Li, John Chang, Gary V. Desir, Wan-Hong Lu, Jian-Jun Mu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectiveRenalase, a novel secretory flavoprotein with amine oxidase activity, is secreted into the blood by the kidneys and is hypothesized to participate in blood pressure (BP) regulation. We investigated the associations of renalase with BP and th
Externí odkaz:
https://doaj.org/article/a93ebb4ad37246bbbc5833cb7129e0ac
Autor:
Basmah Safdar, Melinda Wang, Xiaojia Guo, Charles Cha, Hyung J. Chun, Yanhong Deng, James Dziura, Joe M. El-Khoury, Fred Gorelick, Albert I. Ko, Alfred I. Lee, Robert Safirstein, Michael Simonov, Bin Zhou, Gary V. Desir
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Renalase is a secreted flavoprotein with anti-inflammatory and pro-cell survival properties. COVID-19 is associated with disordered inflammation and apoptosis. We hypothesized that blood renalase levels would correspond to severe COVID-19 and surviva
Externí odkaz:
https://doaj.org/article/d2c603f908be4672a0159684fac8b1b7
Autor:
Stephen Y Wang, Takehiro Takahashi, Alexander B Pine, William E Damsky, Michael Simonov, Yanhua Zhang, Elizabeth Kieras, Christina C Price, Brett A King, Mark D Siegel, Gary V Desir, Alfred I Lee, Akiko Iwasaki, Hyung J Chun
Publikováno v:
PLoS Biology, Vol 19, Iss 8, p e3001373 (2021)
Challenges in using cytokine data are limiting Coronavirus Disease 2019 (COVID-19) patient management and comparison among different disease contexts. We suggest mitigation strategies to improve the accuracy of cytokine data, as we learn from experie
Externí odkaz:
https://doaj.org/article/47065a92e2014c37b9affe9000d8b92f
Autor:
Hesham Elhalawani, Baher Elgohari, Timothy A. Lin, Abdallah S.R. Mohamed, Thomas J. Fitzgerald, Fran Laurie, Kenneth Ulin, Jayashree Kalpathy-Cramer, Thomas Guerrero, Emma B. Holliday, Gregory Russo, Abhilasha Patel, William Jones, Gary V. Walker, Musaddiq Awan, Mehee Choi, Roi Dagan, Omar Mahmoud, Anna Shapiro, Feng-Ming (Spring) Kong, Daniel Gomez, Jing Zeng, Roy Decker, Femke O.B. Spoelstra, Laurie E. Gaspar, Lisa A. Kachnic, Charles R. Thomas, Jr., Paul Okunieff, Clifton D. Fuller
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 15, Iss , Pp 83-92 (2019)
Introduction: Target delineation variability is a significant technical impediment in multi-institutional trials which employ intensity modulated radiotherapy (IMRT), as there is a real potential for clinically meaningful variances that can impact th
Externí odkaz:
https://doaj.org/article/fdbeec815fa241a584403517dfdc590d
Autor:
Yasheen Gao, Melinda Wang, Xiaojia Guo, Joanna Hu, Tian-Min Chen, Sade M B Finn, Jill Lacy, John W Kunstman, Charles H Cha, Melena D Bellin, Marie E Robert, Gary V Desir, Fred S Gorelick
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0250539 (2021)
Dysregulated expression of the secretory protein renalase can promote pancreatic ductal adenocarcinoma (PDAC) growth in animal models. We characterized renalase expression in premalignant and malignant PDAC tissue and investigated whether plasma rena
Externí odkaz:
https://doaj.org/article/df608288a0c2416eaf83a695166bb52d