Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Gary Tarpley"'
Autor:
Robert B. Kargbo, Alexander Sherwood, Andrew Walker, Nicholas V. Cozzi, Raymond E. Dagger, Jessica Sable, Kelsey O’Hern, Kristi Kaylo, Tura Patterson, Gary Tarpley, Poncho Meisenheimer
Publikováno v:
ACS Omega, Vol 5, Iss 27, Pp 16959-16966 (2020)
Externí odkaz:
https://doaj.org/article/48d2c06570584f16b165e38b99e1fef2
Autor:
Tura Patterson, Andrew Walker, Poncho Meisenheimer, Robert B. Kargbo, Raymond E. Dagger, Jessica Sable, Kristi W. Kaylo, Alexander M. Sherwood, Kelsey O’Hern, Nicholas V. Cozzi, Gary Tarpley
Publikováno v:
ACS Omega, Vol 5, Iss 27, Pp 16959-16966 (2020)
ACS Omega
ACS Omega
A second-generation kilogram-scale synthesis of the psychedelic tryptamine psilocybin has been developed. The synthesis was designed to address several challenges first encountered with the scale-up of previously described literature procedures, whic
Publikováno v:
Synthesis. 52:688-694
Described herein is an improved synthesis of 3-[2-(dimethylamino)ethyl]-1H-indol-4-yl dihydrogen phosphate (psilocybin). The protocol outlines: synthesis of multigram quantities of psilocybin, identification of critical in-process parameters, and iso
Autor:
Richard A. Nugent, Donn G. Wishka, Lester A. Dolak, Azhwarsamy Jeganathan, Eric P. Seest, Laurice A. Kopta, Randall G. Stehle, Joel Morris, Wendy L. White, Stephen T. Schlachter, Janice M. Friis, Susan M. Poppe, Wade J. Adams, Murphy Michael J, David R. Graber, Robert A. Olmsted, Fusen Han, John D. Hosley, Cleek Gary J, Richard L. Voorman, Poel Toni-Jo, and W. Gary Tarpley, William Watt, Keiser Bj, Y. Yagi, Kevin Stefanski, Richard C. Thomas, Steven M. Swaney, Thomas M. Castle
Publikováno v:
Journal of Medicinal Chemistry. 41:1357-1360
Autor:
Mariano Busso, Kuo-Chen Chou, W. Gary Tarpley, Kathleen M. Downey, Donna L. Romero, Paul A. Aristoff, Kellie M. Franks, Fritz Reusser, Richelle J. Lemay, Lionel Resnick, Ferenc J. Kezdy, Martin R. Deibel, Irene W. Althaus, Antero G. So, Richard C. Thomas
Publikováno v:
Biochemical Pharmacology. 51:743-750
U-31,355, or 4-amino-2-(benzylthio)-6-chloropyrimidine is an inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) and possesses anti-HIV activity in HIV-1-infected lymphocytes grown in tissue culture. The compound acts
Autor:
Suvit Thaisrivongs, Harvey I. Skulnick, Steve R. Turner, Joseph W. Strohbach, Ruben A. Tommasi, Paul D. Johnson, Paul A. Aristoff, Thomas M. Judge, Ronald B. Gammill, Jeanette K. Morris, Karen R. Romines, Robert A. Chrusciel, Roger R. Hinshaw, Kong-Teck Chong, W. Gary Tarpley, Susan M. Poppe, David E. Slade, Janet C. Lynn, Miao-Miao Horng, Paul K. Tomich, Eric P. Seest, Lester A. Dolak, W. Jeffrey Howe, Gina M. Howard, Francis J. Schwende, Lisa N. Toth, Guy E. Padbury, Grace J. Wilson, Lihua Shiou, Gail L. Zipp, Karen F. Wilkinson, Bob D. Rush, Mary J. Ruwart, Kenneth A. Koeplinger, Zhiyang Zhao, Serena Cole, Renee M. Zaya, Thomas J. Kakuk, Musiri N. Janakiraman, Keith D. Watenpaugh
Publikováno v:
Journal of Medicinal Chemistry. 39:4349-4353
Autor:
Satish K. Sharma, Kenneth B. Rank, Carol A. Bannow, Joseph W. Leone, Alfredo G. Tomasselli, Donna J. Rothrock, Robert L. Heinrikson, Clark W. Smith, Susan M. Poppe, David B. Evans, Naisheng Fan, W. Gary Tarpley
Publikováno v:
Journal of Biological Chemistry. 270:13573-13579
Active, recombinant p68 reverse transcriptase (RT) from human immunodeficiency virus type 2 (HIV-2), with an NH2-terminal extension containing a hexahisti-dine sequence was isolated from extracts of Escherichia coli by immobilized metal affinity chro
Autor:
Kenneth B. Rank, Satish K. Sharma, Richard C. Thomas, Naisheng Fan, W. Gary Tarpley, David B. Evans
Publikováno v:
FEBS Letters. 359:233-238
Bisheteroarylpiperazines (BHAPs) are highly specific inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). BHAP-resistant HIV-1 is sensitized to other classes of nonnucleoside RT inhibitors and this has been primarily
Autor:
Daniel R. Kuritzkes, Joseph J. Eron, Thomas B. Campbell, Richard T. D'Aquila, W. Gary Tarpley, Russell K. Young
Publikováno v:
Journal of Infectious Diseases. 168:318-326
The bisheteroarylpiperazine nonnucleoside reverse transcriptase (RT) inhibitor atevirdine effectively inhibits human immunodeficiency virus type 1 (HIV-1) in vitro. Clinical isolates with a wide range of 50% inhibitory concentrations (IC50s) of zidov