Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Gary Taniguchi"'
Autor:
Boris Gorovits, Gopi Shankar, Steven J. Swanson, Deborah Finco-Kent, Yuchen Barrett, Shalini Gupta, Holly W. Smith, Bonita Rup, Linda Zuckerman, Gary Taniguchi, Anthony Mire-Sluis, Valerie Quarmby, Michael Moxness, Viswanath Devanarayan, Thomas Parish, Elizabeth Shores, Eugen Koren, Christopher Stebbins
Publikováno v:
Journal of Immunological Methods. 333:1-9
The appropriate evaluation of the immunogenicity of biopharmaceuticals is of major importance for their successful development and licensure. Antibodies elicited by these products in many cases cause no detectable clinical effects in humans. However,
Autor:
Eugene Koren, Anthony Mire-Sluis, Steven J. Swanson, Linda Zuckerman, Daniel Wierda, Viswanath Devanarayan, Gary Taniguchi, Mauricio Maia, Elizabeth Shores, Gopi Shankar, Thomas Parish, Yu Chen Barrett, George Scott, Hank Liu
Publikováno v:
Journal of Immunological Methods. 289:1-16
Most biopharmaceutical therapeutics elicit some level of antibody response against the product. This antibody response can, in some cases, lead to potentially serious side effects and/or loss of efficacy. Therefore, the immunogenicity of therapeutic
Publikováno v:
Molecular Genetics and Metabolism. 111:S77
Fabry disease is a life-threatening X-linked genetic disorder caused by deficient activity of the lysosomal enzyme α-galactosidase A. As a result of the enzyme deficiency, glycosphingolipids (GSLs)with terminal α-D-galactosyl moieties, primarily gl