Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gary T. Borrett"'
Autor:
Erica Vit, Jerome F. Hayes, Francois-Rene Alexandre, Cyril B. Dousson, Christophe Claude Parsy, David D. Pascoe, Catherine Caillet, Marie-Pierre Lioure, Neil Hodnett, Elodie Rosinovsky, John Edward Richardson, Guillaume Bret, Stéphanie Bot, Agnès Amador, Gary T. Borrett, Bernadette Choudary, Arlène Roland, Daniel Da Costa, Alan Ironmonger, John D. Hayler, Augustine Ochen, Séverine Bonaric, David Colclough, Richard K. Bellingham
Publikováno v:
Organic Process Research & Development. 22:200-206
A new and improved synthetic route to an intermediate in the synthesis of the phosphinate ester GSK2248761A is described. In the key step, we describe the first process-scale example of a palladium-catalyzed phosphorus–carbon coupling to give the e
Autor:
Gary T. Borrett, Graham R. Slater, Stephen A. Hermitage, Ian P. Andrews, Peter M. Kincey, Smith Neil, Mahesh J. Sanganee, Geracimos Rassias
Publikováno v:
Organic Process Research & Development. 13:774-780
The original medicinal chemistry synthesis of an iNOS inhibitor presented several challenges that had to be overcome in order to constitute a supply route suitable for operation on a multikilo scal...
Publikováno v:
ChemInform. 24
The trans-adduct 8 derived from indene and N, N-dichlorourethane serves as a precursor for the cis-1, 2-diaminoindane 6 and the trans-diamines 7 and 14. Conversion of 6 and 14 into the triazabenzocycloheptafluorenes 1 and 2, respectively, via the ind
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1299
The trans-adduct 8 derived from indene and N, N-dichlorourethane serves as a precursor for the cis-1, 2-diaminoindane 6 and the trans-diamines 7 and 14. Conversion of 6 and 14 into the triazabenzocycloheptafluorenes 1 and 2, respectively, via the ind