Výsledky vyhledávání - "Gary T Burger"

Interspecies Variations in the Histology of Toxicologically Important Areas in the Larynges of CRL:CD Rats and Syrian Golden Hamsters*†

Autor: Roger A. Renne, John W. Sagartz, Gary T. Burger

Publikováno v: Toxicologic Pathology. 21:542-546

Specific regions in the rodent larynx exhibit cellular changes in response to inhaled xenobiotics. These regions include the base of the epiglottis, ventral pouch, and medial surfaces of the vocal processes of the arytenoid cartilages. There are inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8b70cadcfeb0b8b7a99b6d086d8843
https://doi.org/10.1177/019262339302100604

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2-Week and 13-Week Inhalation Studies of Aerosolized Glycerol in Rats

Autor: Gary T. Burger, Ray L. Buschbom, Alfred P. Wehner, H. S. Deford, Roger A. Renne, R. L. Suber, Arnold T. Mosberg, A. W. Hayes, H. A. Ragan, B. J. Greenspan, R. B. Westerberg

Publikováno v: Inhalation Toxicology. 4:95-111

The potential toxicity of aerosolized glycerol was studied by 2-wk and 13-wk nose-only inhalation exposures in Sprague-Dawley-derived (Cr1:CD) rats. In the first study, 10 ratslsedgroup received 10...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dfb40939d34d7739012cc76f536e382e
https://doi.org/10.3109/08958379209145307

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Histological Sectioning of the Rodent Larynx for Inhalation Toxicity Testing

Autor: Mark A. Forsell, John W. Sagartz, Arpad J. Madarasz, Christopher R. E. Coggins, Paul H. Ayres, Gary T. Burger

Publikováno v: Toxicologic Pathology. 20:118-121

In rodents, the larynx is a major site of histopathologic alteration following inhalation exposure to particulates, vapors, and aerosols. Specifically, the epithelial lining of a narrowly delineated region on the ventral floor of the larynges of rats

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9eeb0a2cc809a383508696e20a8100
https://doi.org/10.1177/019262339202000115

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Comparative genotoxicity testing of mainstream whole smoke from cigarettes which burn or heat tobacco

Autor: Gary T. Burger, Chin K. Lee, David J. Doolittle, A. Wallace Hayes

Publikováno v: Mutation Research/Genetic Toxicology. 242:37-45

The genotoxic potential of mainstream whole smoke (MWS) from cigarettes which heat tobacco (TEST) was compared to the genotoxic potential of MWS from a cigarette which burns tobacco (REFERENCE). MWS was collected from a University of Kentucky 1R4F ci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c1b35ab0df21df1585c1c18547d867
https://doi.org/10.1016/0165-1218(90)90097-l

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Chemical and Biological Studies of a Cigarette That Heats Rather Than Burns Tobacco

Autor: David J. Doolittle, Michael F. Borgerding, A. Wallace Hayes, J. Donald deBethizy, Johnnie R. Hayes, John Hughes Reynolds, Kevin T. McManus, Riley A. Davis, Gary T. Burger, Carolyn A. Rahn, John H. Robinson

Publikováno v: The Journal of Clinical Pharmacology. 30:755-763

Cigarettes can be developed that heat rather than burn tobacco. Such products would be expected to have less "tar" and other combustion products than cigarettes that burn tobacco. With one product of this type, benzo(a)pyrene, N-nitrosamines, phenoli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d8da77fe526b1c537e63e79a004d65
https://doi.org/10.1002/j.1552-4604.1990.tb03639.x

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Genetic toxicology studies comparing the activity of sidestream smoke from cigarettes which burn or only heat tobacco

Autor: J. L. Ivett, C. J. Rudd, Jon C. Mirsalis, Gary T. Burger, David J. Doolittle, Edward S. Riccio, A.W. Hayes, Chin K. Lee

Publikováno v: Mutation Research/Genetic Toxicology. 240:59-72

The results of in vitro genetic toxicology studies of sidestream cigarette smoke (SSCS) from cigarettes which heat but do not burn tobacco were compared to those of sidestream smoke from cigarettes which burn tobacco. SSCSs from 5 cigarettes were com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79228a286e5b553cf7fd692e492b0ff9
https://doi.org/10.1016/0165-1218(90)90008-p

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Comparative Subchronic Inhalation Bioassay in Hamsters of a Cicarette that only Heats Tobacco

Autor: H. S. Deford, Arnold T. Mosberg, Roger A. Renne, B. J. Greenspan, Ray L. Buschbom, Alfred P. Wehner, H. A. Ragan, A. W. Hayes, Gary T. Burger, Christopher R. E. Coggins, R. B. Mterberg, C. W. Wright

Publikováno v: Inhalation Toxicology. 2:255-283

This subchronic inhalation study compared the effects of nose-only exposure in hamsters to the smoke from the University of Kentucky 1R4F reference cigarette, which burns tobacco, and a test cigarette, which only heats tobacco. Thirty-four Syrian gol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be36fc541ebac7770690e11075a2e341
https://doi.org/10.3109/08958379009145258

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Histopathology, Urine Mutacenicity, and Bone Marrow Cytocenetics of Mice Exposed Nose-Only to Smoke from Cigarettes that Burn or Heat Tobacco

Autor: A. Wallace Hayes, Chin K. Lee, Christopher R. E. Coggins, Arnold T. Mosberg, Paul H. Ayres, David C. Bolin, Gary T. Burger, David J. Doolittle

Publikováno v: Inhalation Toxicology. 2:407-431

Male and female B6C3F1 mice were exposed nose-only to smoke from a test cigarette that heats tobacco, or from a reference cigarette that burns tobacco. Cigarette smoke was generated by a smoking machine, and the concentrations of wet total particulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fba29ced7b7bce0fcee434f854d100b3
https://doi.org/10.3109/08958379009145266

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Myoepithelioma, Salivary Glands, Mouse

Autor: James W. Townsend, Gary T. Burger, Charles H. Frith

Publikováno v: Digestive System ISBN: 9780944398753
Digestive System ISBN: 9783642969126
Digestive System ISBN: 9783642644214

Myoepitheliomas usually occur in the major salivary glands and appear in the subcutis of the ventral neck. They are seen as reddish-yellow masses, which may be solid or a mixture of solid and cystic. The cystic structures are filled with mucoid mater

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d742ea44b673159714f7d2ed13cbb8d
https://doi.org/10.1007/978-3-662-25996-2_34

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Bioassay for carcinogenicity of rotenone in female Wistar rats

Autor: David L. Greenman, Ralph L. Kodell, Gary T. Burger, William T. Allaben

Publikováno v: Fundamental and applied toxicology : official journal of the Society of Toxicology. 20(3)

Rotenone, a pesticide extracted from the Derris root, consistently was reported by a series of investigators to have induced mammary fibroadenomas in female Wistar rats when administered ip or by gavage in a sunflower (SF) oil or SF oil:chloroform ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506ac885cb8961ecd99edf8ab0f074f3
https://pubmed.ncbi.nlm.nih.gov/8504913

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