Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Gary S. Bird"'
Autor:
Lucía Núñez, James W. Putney, Gary S. Bird, Enrique Pérez-Riesgo, Elena Hernando-Pérez, Carlos Villalobos
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1866:1124-1136
Store operated Ca2+ entry (SOCE) is the most important Ca2+ entry pathway in non-excitable cells. However, SOCE can also play a pivotal role in excitable cells such as anterior pituitary (AP) cells. The AP gland contains five different cell types tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47458897c2c0170ce150724eed13e322
https://doi.org/10.1016/j.bbamcr.2018.11.006
https://doi.org/10.1016/j.bbamcr.2018.11.006
Autor:
Yu-Ping Lin, Matthias A. Hediger, Carina Monico, Rajesh Bhardwaj, Nader Amin, Pulak Kar, Charles J. Tucker, Gary S. Bird, Anant B. Parekh
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Kar, Pulak; Lin, Yu-Ping; Bhardwaj, Rajesh; Tucker, Charles J; Bird, Gary S; Hediger, Matthias A.; Monico, Carina; Amin, Nader; Parekh, Anant B (2021). The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca2+ entry. Proceedings of the National Academy of Sciences of the United States of America-PNAS, 118(19) National Academy of Sciences NAS 10.1073/pnas.2012908118
Kar, Pulak; Lin, Yu-Ping; Bhardwaj, Rajesh; Tucker, Charles J; Bird, Gary S; Hediger, Matthias A.; Monico, Carina; Amin, Nader; Parekh, Anant B (2021). The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca2+ entry. Proceedings of the National Academy of Sciences of the United States of America-PNAS, 118(19) National Academy of Sciences NAS 10.1073/pnas.2012908118
Significance Store-operated Orai1 Ca2+ channels are a major route for trigger Ca2+ in immune cells. Local Ca2+ entry through the channels activates NFAT transcription factors, which in turn increase expression of chemokines and cytokines that orchest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3c4a83acd17943de98517312d7603c
http://europepmc.org/articles/PMC8126794
http://europepmc.org/articles/PMC8126794
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20542 (2011)
BackgroundExposure to cadmium is associated with human pathologies and altered gene expression. The molecular mechanisms by which cadmium affects transcription remain unclear. It has been proposed that cadmium activates transcription by altering intr
Externí odkaz:
https://doaj.org/article/22c73d72eb0e4120b11030704808799d
Autor:
Yoichi Hayakawa, Na Young Yi, Outa Uryu, Huanchen Wang, Masanori Ochiai, Stephen B. Shears, Eui Jae Sung, Gary S. Bird, Masasuke Ryuda, Molly E. Cook, James W. Putney, Hitoshi Matsumoto
Publikováno v:
Proceedings of the National Academy of Sciences. 114:13786-13791
A systems-level understanding of cytokine-mediated, intertissue signaling is one of the keys to developing fundamental insight into the links between aging and inflammation. Here, we employed Drosophila, a routine model for analysis of cytokine signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ebe352c1a28990cb89474fddf0b5d13
https://doi.org/10.1073/pnas.1712453115
https://doi.org/10.1073/pnas.1712453115
Autor:
Lucía, Núñez, Gary S, Bird, Elena, Hernando-Pérez, Enrique, Pérez-Riesgo, James W, Putney, Carlos, Villalobos
Publikováno v:
Biochim Biophys Acta Mol Cell Res
Store operated Ca(2+) entry (SOCE) is the most important Ca(2+) entry pathway in non-excitable cells. However, SOCE can also play a pivotal role in excitable cells such as anterior pituitary (AP) cells. The AP gland contains five different cell types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::660ff8130013471ffe3cf2281d8e3a05
https://pubmed.ncbi.nlm.nih.gov/30452936
https://pubmed.ncbi.nlm.nih.gov/30452936
Publikováno v:
Biophysical Journal. 116:236a-237a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c4aae4dc0e4541093fb7555177588af
https://doi.org/10.1016/j.bpj.2018.11.1299
https://doi.org/10.1016/j.bpj.2018.11.1299
Autor:
Eui Jae, Sung, Masasuke, Ryuda, Hitoshi, Matsumoto, Outa, Uryu, Masanori, Ochiai, Molly E, Cook, Na Young, Yi, Huanchen, Wang, James W, Putney, Gary S, Bird, Stephen B, Shears, Yoichi, Hayakawa
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(52)
Invertebrates are productive models for understanding basic molecular principles that link cytokine-mediated inflammatory pathways to aging in humans. Here, we use a high-throughput dsRNA screen to determine that the multifunctional Drosophila cytoki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17e0f210544cc4d754a363bbe696c2a5
https://pubmed.ncbi.nlm.nih.gov/29229844
https://pubmed.ncbi.nlm.nih.gov/29229844
Autor:
Gary S. Bird, James W. Putney
In general, calcium signaling in non-excitable cells is primarily initiated by the activation of surface membrane receptors coupled to phospholipase C (PLC) and stimulates a calcium signaling process that is complex both spatially and temporally, inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8487b1a0c3fa95239345acf0857d8c2d
https://doi.org/10.1201/9781315152592-16
https://doi.org/10.1201/9781315152592-16
Autor:
Felicity M. Davis, Gary S. Bird, Natacha Steinckwich-Besancon, Pooja N. Desai, Takuro Numaga-Tomita, Diane M. D’Agostin, Shilan Wu, James W. Putney
Publikováno v:
JW, P, N, S-B, T, N-T, FM, D, PN, D, DM, DA, S, W & GS, B 2017, ' The functions of store-operated calcium channels. ', Biochimica et biophysica acta. Molecular cell research . https://doi.org/10.1016/j.bbamcr.2016.11.028
Store-operated calcium channels provide calcium signals to the cytoplasm of a wide variety of cell types. The basic components of this signaling mechanism include a mechanism for discharging Ca 2 + stores (commonly but not exclusively phospholipase C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef54c219037144f25d452125edf5b02b
https://pure.au.dk/portal/da/publications/the-functions-of-storeoperated-calcium-channels(c9790efb-aad9-49f8-ad34-35f4f4729a34).html
https://pure.au.dk/portal/da/publications/the-functions-of-storeoperated-calcium-channels(c9790efb-aad9-49f8-ad34-35f4f4729a34).html
Autor:
Pooja N. Desai, Juan Xing, Gary S. Bird, John G. Petranka, James W. Putney, Felicity M. Davis
Publikováno v:
The Journal of Physiology. 592:927-939
Lacrimal glands function to produce an aqueous layer, or tear film, that helps to nourish and protect the ocular surface. Lacrimal glands secrete proteins, electrolytes and water, and loss of gland function can result in tear film disorders such as d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fdc54586743ea185bb9f6fe8f30d783
https://doi.org/10.1113/jphysiol.2013.267740
https://doi.org/10.1113/jphysiol.2013.267740