Zobrazeno 1 - 10
of 333
pro vyhledávání: '"Gary S, Hoffman"'
Autor:
Paul A. Monach, Roscoe L. Warner, Robert Lew, Gunnar Tómasson, Ulrich Specks, John H. Stone, Fernando C. Fervenza, Gary S. Hoffman, Cees G. M. Kallenberg, Carol A. Langford, Philip Seo, E. William St. Clair, Robert Spiera, Kent J. Johnson, Peter A. Merkel
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 2, Pp 168-176 (2022)
Objective Improved biomarkers of current disease activity and prediction of relapse are needed in antineutrophil cytoplasmic antibody–associated vasculitis (AAV). For clinical relevance, biomarkers must perform well longitudinally in patients on tr
Externí odkaz:
https://doaj.org/article/1b4d66b46e4b402cb73650c340d67054
Autor:
Gary W. Procop, Charis Eng, Alison Clifford, Alexandra Villa-Forte, Leonard H. Calabrese, Eric Roselli, Lars Svensson, Douglas Johnston, Gosta Pettersson, Edward Soltesz, Lisa Lystad, Julian D. Perry, Alexander Blandford, Deborah A. Wilson, Gary S. Hoffman
Publikováno v:
Pathogens and Immunity, Vol 2, Iss 2, Pp 228-238 (2017)
Objective: It is controversial whether microorganisms play a role in the pathogenesis of large and medium vessel vasculitides (eg, giant cell arteritis [GCA], Takayasu arteritis [TAK] and focal idiopathic aortitis [FIA]). Recent studies have reported
Externí odkaz:
https://doaj.org/article/0677ac503dc84e1ab63b8ea4c08d15cd
Autor:
Lucy Lin, Mavis R. Swerdel, Michael P. Lazaropoulos, Gary S. Hoffman, Alana J. Toro-Ramos, Jennifer Wright, Howard Lederman, Jianmin Chen, Jennifer C. Moore, Ronald P. Hart
Publikováno v:
Stem Cell Reports, Vol 5, Iss 6, Pp 1097-1108 (2015)
A spontaneously reverted iPSC line was identified from an A-T subject with heterozygous ATM truncation mutations. The reverted iPSC line expressed ATM protein and was capable of radiation-induced phosphorylation of CHK2 and H2A.X. Genome-wide SNP ana
Externí odkaz:
https://doaj.org/article/94721fb9df1c44888e21a588cc88d000
Autor:
Gabriele Gamerith, Finn Mildner, Peter A Merkel, Kristina Harris, Laura Cooney, Noha Lim, Robert Spiera, Philip Seo, Carol A Langford, Gary S Hoffman, E William St Clair, Fernando C Fervenza, Paul Monach, Steven R Ytterberg, Duvuru Geetha, Arno Amann, Dominik Wolf, Ulrich Specks, John H Stone, Andreas Kronbichler
Publikováno v:
Annals of the rheumatic diseases.
ObjectivesWe investigated whether soluble immune checkpoints (sICPs) predict treatment resistance, relapse and infections in patients with antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV).MethodsPlasma sICP concentrations from ava
Autor:
Ulrich Specks, Gary S. Hoffman, Paul A. Monach, Peter A. Merkel, Kent J. Johnson, Robert Spiera, John H. Stone, Gunnar Tomasson, Carol A. Langford, Roscoe L. Warner, Robert A. Lew, Fernando C. Fervenza, E. William St. Clair, Philip Seo, Cees G. M. Kallenberg
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 2, Pp 168-176 (2022)
ACR open rheumatology, 4(2), 168-176. Wiley
ACR open rheumatology, 4(2), 168-176. Wiley
Objective Improved biomarkers of current disease activity and prediction of relapse are needed in antineutrophil cytoplasmic antibody-associated vasculitis (AAV). For clinical relevance, biomarkers must perform well longitudinally in patients on trea
Autor:
Gary S. Hoffman
Publikováno v:
Clinical and Developmental Immunology, Vol 11, Iss 3-4, Pp 275-279 (2004)
Studies of autoimmune diseases have not yet elucidated why certain organs or vessels become the objects of injury while others are spared. This paper will explore the hypothesis that important differences exist in regions of the aorta that determi
Externí odkaz:
https://doaj.org/article/05a22e79b30243b785d41214423ee1c6
Autor:
Ruchika Goel, Curry L. Koening, Antoine G. Sreih, Christian Pagnoux, Carol A. Langford, Sathish Kumar, Aswin Nair, Simon Carette, Gary S. Hoffman, Paul A. Monach, Raheesh Ravindran, Steven R. Ytterberg, George Joseph, Peter C. Grayson, Kathleen Maksimowicz-McKinnon, Debashish Danda, Kenneth J. Warrington, Larry W. Moreland, David Cuthbertson, K. Bates Gribbons, Philip Seo, Carol A. McAlear, Nader Khalidi, Kaitlin A. Quinn, Peter A. Merkel
Publikováno v:
Rheumatology (Oxford)
Objectives To develop and replicate, using data-driven methods, a novel classification system in Takayasu’s arteritis based on distribution of arterial lesions. Methods Patients were included from four international cohorts at major academic centre
Autor:
Jae Il Shin, Andreas Kronbichler, Carol A. Langford, Paul A. Monach, E. William St. Clair, Philip Seo, John H. Stone, Cees G. M. Kallenberg, Duvuru Geetha, Gert Mayer, Gary S. Hoffman, Fernando C. Fervenza, Robert Spiera, Peter A. Merkel, Ulrich Specks, Karina A. Keogh, Steven R. Ytterberg, Johannes Leierer, Paul Brunetta
Publikováno v:
Arthritis & Rheumatology, 71(11), 1888-1893. Wiley
Arthritis & Rheumatology (Hoboken, N.j.)
Arthritis & Rheumatology (Hoboken, N.j.)
Objective To assess the frequency of venous thromboembolism (VTE) events in the Rituximab in Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (RAVE) trial and identify novel potential risk factors. Methods VTE events in 197 patients e
Autor:
Douglas R. Johnston, Gary S. Hoffman, Leonard H. Calabrese, Alexandra Villa-Forte, Eric E. Roselli, Alison H. Clifford, Edward G. Soltesz, Gösta B. Pettersson, Roshan Padmanabhan, Charis Eng, Lars G. Svensson, Eugene H. Blackstone, Ted M Getz
Publikováno v:
Pathogens and Immunity, Vol 4, Iss 1, Pp 105-123 (2019)
Pathogens & Immunity
Pathogens & Immunity
Objective: We sought to characterize microbiomes of thoracic aortas from patients with non-infectious aortitis due to giant cell arteritis (GCA) and clinically isolated aortitis (CIA) and to compare them to non-inflammatory aorta aneurysm controls. W
Autor:
Albert Y. Benneh, Gary S. Hoffman, Ziad C. Sifri, Philip M. Mshelbwala, Benedict C. Nwomeh, Vennila Padmanaban, Fatemeh P. Parvin-Nejad
Publikováno v:
Surgery. 170(2)
Background The global burden of disease treatable by surgical subspecialists remains an outstanding area of need, and yet little is known about the subspecialist workforce worldwide, especially in sub-Saharan Africa. This study aims to quantify the s