Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Gary R. Kunkel"'
Autor:
Laura Huning, Gary R. Kunkel
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background ZNF143 is an important transcriptional regulator protein conserved in metazoans and estimated to bind over 2000 promoter regions of both messenger RNA and small nuclear RNA genes. The use of zebrafish is a useful model system to s
Externí odkaz:
https://doaj.org/article/579ba7d670e24071a9ac4c06de8b1b7f
Publikováno v:
Biochemical and Biophysical Research Communications. 532:190-194
Chromodomain-Helicase-DNA-binding protein 8 (CHD8) is a chromatin remodeler that is central to regulation of gene expression pathways during brain development. Many loss-of-function mutations in transcribed regions of the chd8 gene have been identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef6a5cff3db2f52b6feac4c1d439831
https://doi.org/10.1016/j.bbrc.2020.08.051
https://doi.org/10.1016/j.bbrc.2020.08.051
Publikováno v:
Gene. 641:303-309
Chromodomain-Helicase-DNA binding protein 8 (CHD8) is a member of a large family of eukaryotic ATP-dependent chromatin remodeling complexes. Loss of function alleles of human chd8 are correlated with autism spectrum disorder. The CHD subfamily member
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9991db6d69b7f8202783d118a241097
https://doi.org/10.1016/j.gene.2017.10.058
https://doi.org/10.1016/j.gene.2017.10.058
Publikováno v:
Gene. 421:89-94
Promoters for vertebrate small nuclear RNA (snRNA) genes contain a relatively simple array of transcriptional control elements, divided into proximal and distal regions. Most of these genes are transcribed by RNA polymerase II (e.g., U1, U2), whereas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1417d2b33dfa1d365a245e88e5d0a12f
https://doi.org/10.1016/j.gene.2008.06.019
https://doi.org/10.1016/j.gene.2008.06.019
Publikováno v:
Genomics. 83:119-129
Aldehyde reductase is involved in the reductive detoxification of reactive aldehydes that can modify cellular macromolecules. To analyze the mechanism of basal regulation of aldehyde reductase expression, we cloned the murine gene and adjacent regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05cda30535ab271c88eaa83fe8c1ca71
https://doi.org/10.1016/s0888-7543(03)00213-1
https://doi.org/10.1016/s0888-7543(03)00213-1
Publikováno v:
BMC Molecular Biology
BMC Molecular Biology, Vol 13, Iss 1, p 3 (2012)
BMC Molecular Biology, Vol 13, Iss 1, p 3 (2012)
Background ZNF143 is a sequence-specific DNA-binding protein that stimulates transcription of both small RNA genes by RNA polymerase II or III, or protein-coding genes by RNA polymerase II, using separable activating domains. We describe phenotypic e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c9d409f0ac6d300200d30a2a44fe4f
https://doi.org/10.1186/1471-2199-13-3
https://doi.org/10.1186/1471-2199-13-3
Publikováno v:
Gene. 148:269-275
The proximal promoter of a human U6 small nuclear RNA (snRNA)-encoding gene contains two separate elements, the proximal sequence element (PSE) and the TATA box. We investigated the interaction of the PSE- and TATA-binding proteins (PBP and TBP) with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5676e06d811ec9d43b1007497a284dc
https://doi.org/10.1016/0378-1119(94)90698-x
https://doi.org/10.1016/0378-1119(94)90698-x
Autor:
Andras Perl, Gary R. Kunkel, Graciela B. Sala-Newby, Andrew C. Newby, Ivette Hernández-Negrete, Mark Bond
Publikováno v:
The Biochemical journal. 436(1)
Cell adhesion is essential for cell cycle progression in most normal cells. Loss of adhesion dependence is a hallmark of cellular transformation. The F-box protein Skp2 (S-phase kinase-associated protein 2) controls G1–S-phase progression and is su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5b41e6142dce0ed6ca917b15c5b9af
https://pubmed.ncbi.nlm.nih.gov/21352097
https://pubmed.ncbi.nlm.nih.gov/21352097
Autor:
Gary R. Kunkel, D.A. Danzeiser
Publikováno v:
Journal of Biological Chemistry. 267:14250-14258
Vertebrate U6 small nuclear RNA (snRNA) loci exemplify a novel class of polymerase III-transcribed genes that lack an intragenic control region (ICR). Instead important transcriptional control elements are located in the 5‘-flanking region and rese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b042b1e25ba4e8a25c55cd2042b4b0d1
https://doi.org/10.1016/s0021-9258(19)49705-6
https://doi.org/10.1016/s0021-9258(19)49705-6
Autor:
Gary R. Kunkel
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1088:1-9
Revue traitant de la structure et de l'organisation du promoteur des genes de classe III des Eucaryotes (codant pour les ARN 55, VA, U6 et 75 K). Analyse de leur transcription grâce a la RNA polymerase pol III. Proposition d'un schema precisant les
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e24edb5e2249eadb75ba00ea15becdb
https://doi.org/10.1016/0167-4781(91)90146-d
https://doi.org/10.1016/0167-4781(91)90146-d