Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Gary R. Hutchison"'
Autor:
Jennifer A. Fraser, Sadie Kemp, Lesley Young, Mark Ross, Morag Prach, Gary R. Hutchison, Eva Malone
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Neutrophil surveillance is central to nanoparticle clearance. Silver nanoparticles (AgNP) have numerous uses, however conflicting evidence exists as to their impact on neutrophils and whether they trigger damaging inflammation. Neutrophil’
Externí odkaz:
https://doaj.org/article/61fcc56d8c0947fba710c0fa6677bcfa
Autor:
Christopher Green, Antoaneta Bilyanska, Mags Bradley, Jason Dinsdale, Lorraine Hutt, Thomas Backhaus, Frank Boons, David Bott, Chris Collins, Sarah E. Cornell, Mark Craig, Michael Depledge, Bob Diderich, Richard Fuller, Tamara S. Galloway, Gary R. Hutchison, Nicola Ingrey, Andrew C. Johnson, Rachael Kupka, Peter Matthiessen, Robin Oliver, Stewart Owen, Susan Owens, John Pickett, Sam Robinson, Kerry Sims, Pete Smith, John P. Sumpter, Svetlana Tretsiakova‐McNally, Mengjiao Wang, Tom Welton, Katherine J. Willis, Iseult Lynch
Publikováno v:
Environmental Toxicology and Chemistry. 42:1212-1228
Data Availability Statement: All data are included in the Supporting Information for publication online. Supporting Information is available online at https://setac.onlinelibrary.wiley.com/doi/10.1002/etc.5620#support-information-section . Copyright
Autor:
Robert Fraser, Susan Owens, Gary R Hutchison, Peter Matthiessen, Richard J. Murphy, Chris D. Collins, Michael H. Depledge, John P. Sumpter, Andrew C. Johnson
Publikováno v:
Environment International, Vol 137, Iss, Pp-(2020)
© 2020 The Authors Chemicals policies have spawned a wide range of regulations aimed at limiting damage to the environment and human health. Most instruments are reactive and fragmented. We propose a simple underpinning philosophy, “Do no harm”,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2f93b6e7f69207fef17d089a2f1523
Autor:
Richard A. Anderson, Laura Kennedy, Chris McKinnell, Matthew S. Jobling, Ana Calarrao, Sander van den Driesche, Rod T. Mitchell, Richard M. Sharpe, Gary R. Hutchison, Lenka Hrabalkova, Sheila Macpherson
Publikováno v:
van den Driesche, S, McKinnell, C, Calarrão, A, Kennedy, L, Hutchison, G R, Hrabalkova, L, Jobling, M S, Macpherson, S, Anderson, R A, Sharpe, R M & Mitchell, R T 2015, ' Comparative Effects of Di(n-Butyl) Phthalate Exposure on Fetal Germ Cell Development in the Rat and in Human Fetal Testis Xenografts ', Environmental Health Perspectives . https://doi.org/10.1289/ehp.1408248
Environmental Health Perspectives
Environmental Health Perspectives
Background Phthalate exposure induces germ cell effects in the fetal rat testis. Although experimental models have shown that the human fetal testis is insensitive to the steroidogenic effects of phthalates, the effects on germ cells have been less e
Autor:
Börje Sellergren, Keld Alstrup Jensen, Dagmar Bilanicova, Ali Kermanizadeh, Renie K. Birkedal, Vicki Stone, Antonio Marcomini, Gary R Hutchison, Håkan Wallin, Giulio Pojana, Birgit K Gaiser
Publikováno v:
Nanotoxicology
Effects on the liver C3A cell line treated with a panel of engineered nanomaterials (NMs) consisting of two zinc oxide particles (ZnO; coated 100 nm and uncoated 130 nm), two multi-walled carbon nanotubes (MWCNTs), one silver (Ag < 20 nm), one 7 nm a
Publikováno v:
International Journal of Andrology. 34:e386-e396
Summary Environmental factors are implicated in increased incidence of human testicular germ-cell cancer (TGCC). TGCC has foetal origins and may be one component of a testicular dysgenesis syndrome (TDS). Certain phthalates induce TDS in rats, includ
Autor:
Karin Aschberger, S. M. Hankin, Vicki Stone, Sheona Peters, Gary R Hutchison, Helinor Jane Johnston, Frans M Christensen
Publikováno v:
Nanotoxicology. 4:207-246
This critical review of the available human health safety data, relating to carbon nanotubes (CNTs), was conducted in order to assess the risks associated with CNT exposure. Determining the toxicity related to CNT exploitation is of great relevance a
Autor:
Sander van den Driesche, Amanda J. Drake, Hayley M. Scott, Richard M. Sharpe, Jonathan R. Seckl, Gary R. Hutchison
Publikováno v:
Endocrinology. 150:5055-5064
Common male reproductive abnormalities including cryptorchidism, hypospadias, and low sperm counts may comprise a testicular dysgenesis syndrome (TDS), resulting from fetal testis dysfunction during a critical developmental period involving reduced a
Autor:
Chris McKinnell, Hayley M. Scott, Matthew S. Jobling, Richard M. Sharpe, Amanda J. Drake, Gary R. Hutchison
Publikováno v:
Endocrinology. 149:5280-5287
Fetal androgen action is an important determinant of Sertoli cell (SC) number at birth. Androgens “program” reproductive tract development in rats between embryonic d (e) 15.5 and e17.5 (“male programming window”), and this is reflected for l
Autor:
Matt Jobling, I. Kim Mahood, Marion F Walker, Richard M. Sharpe, Chris McKinnell, J. Ian Mason, Hayley M. Scott, Gary R. Hutchison
Publikováno v:
International Journal of Andrology. 31:103-111
A testicular dysgenesis-like syndrome is induced in rats by fetal exposure to di(n-butyl) phthalate (DBP). A key feature of this is the formation of focal dysgenetic areas comprising malformed seminiferous cords/tubules and intratubular Leydig cells