Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Gary R. Hayes"'
Autor:
Raina N Fichorova, Yujin Lee, Hidemi S Yamamoto, Yuko Takagi, Gary R Hayes, Russell P Goodman, Xenia Chepa-Lotrea, Olivia R Buck, Ryan Murray, Tomasz Kula, David H Beach, Bibhuti N Singh, Max L Nibert
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48418 (2012)
Wide-spread protozoan parasites carry endosymbiotic dsRNA viruses with uncharted implications to the human host. Among them, Trichomonas vaginalis, a parasite adapted to the human genitourinary tract, infects globally ∼250 million each year renderi
Externí odkaz:
https://doaj.org/article/a371a654c5c347e49be077f5808b1211
Autor:
Hassan Y. Dawood, Gary R. Hayes, Stanthia Ryan, Titilayo Fashemi, Noah Beatty, Sachiko Sato, Evan Foley, Bibhuti N. Singh, Guillaume St-Pierre, Hidemi S. Yamamoto, Raina N. Fichorova
Publikováno v:
The Journal of Biological Chemistry
Trichomoniasis is the most common non-viral sexually transmitted infection caused by the vaginotropic extracellular protozoan parasite Trichomonas vaginalis. The infection is recurrent, with no lasting immunity, often asymptomatic, and linked to preg
Autor:
Rosaria Rita Sassi, John J. Lucas, Ulf Sommer, Radiana T. Trifonova, Raina N. Fichorova, Catherine E. Costello, Bibhuti N. Singh, Nelly Viseux, Gary R. Hayes, Ekaterina Mirgorodskaya
Publikováno v:
Glycoconjugate Journal. 26:3-17
Trichomonas vaginalis causes the most common non-viral sexually transmitted infection linked to increased risk of premature birth, cervical cancer and HIV. This study defines molecular domains of the parasite surface glycoconjugate lipophosphoglycan
Autor:
Robert O. Gilbert, John J. Lucas, Shelley Kummer, Gary R. Hayes, Bibhuti N. Singh, David H. Beach
Publikováno v:
Microbial Pathogenesis. 44:197-203
Trichomonas vaginalis is an understudied parasitic organism whose mechanisms of pathogenesis remain unclear. The adherence to host cells, the induction of host cell cytotoxicity and protease activity are all, however, thought to be contributing facto
Autor:
John J. Lucas, Bibhuti N. Singh, Ulf Sommer, Gary R. Hayes, Catherine E. Costello, David H. Beach, Robert O. Gilbert
Publikováno v:
Journal of Biological Chemistry. 280:23853-23860
A secreted cysteine protease (CP) fraction from Trichomonas vaginalis is shown here to induce apoptosis in human vaginal epithelial cells (HVEC) and is analyzed by mass spectrometry. The trichomonad parasite T. vaginalis causes one of the most common
Publikováno v:
Biochemistry. 36:5276-5284
The human transferrin receptor (TfR) has three N-linked oligosaccharides. A combination of site-directed mutagenesis and carbohydrate and protein chemistry was used to characterize the structures of the N-linked oligosaccharides and to map their loca
Publikováno v:
Diabetes. 40:300-303
Clustering of cell-surface insulin receptors has led to the speculation that intermolecular phosphorylation of unoccupied receptors catalyzed by ligand-occupied receptors within the cluster could be a mechanism by which the insulin-binding signal is
Autor:
Yongchool Choe, Hardip K. Kalsi, John J. Lucas, Gary R. Hayes, Robert O. Gilbert, Charles S. Craik, Bibhuti N. Singh
Publikováno v:
Archives of biochemistry and biophysics. 477(2)
Tritrichomonas foetus is a serious veterinary pathogen, causing bovine trichomoniasis and affecting cattle herds world-wide, resulting in inflammation of the genital tract, infertility and huge economic losses. The parasite secretes a cysteine protea
Autor:
Raina N. Fichorova, Radiana T. Trifonova, Robert O. Gilbert, Catherine E. Costello, John J. Lucas, Gary R. Hayes, Bibhuti N. Singh
Publikováno v:
Infection and immunity. 74(10)
Trichomonas vaginalisis one of the most common nonviral sexually transmitted human infections and, worldwide, has been linked to increased incidence of human immunodeficiency virus type 1 transmission, preterm delivery, low birth weight, cervical can
Publikováno v:
American journal of veterinary research. 66(7)
Objective—To evaluate the cytopathic effects of Tritrichomonas foetus and a purified cysteine protease (ie, CP30) of T foetus on cultured bovine uterine epithelial cells (BUECs) in vitro. Sample Population—10 reproductive tracts were obtained fro