Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gary Pettman"'
Autor:
Charlotte L, Godfrey, Emma J, Mead, Olalekan, Daramola, Sarah, Dunn, Diane, Hatton, Ray, Field, Gary, Pettman, C Mark, Smales
Publikováno v:
Biotechnology journal. 12(8)
mRNA translation is a key process determining growth, proliferation and duration of a Chinese hamster ovary (CHO) cell culture and influences recombinant protein synthesis rate. During bioprocessing, CHO cells can experience stresses leading to repro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1677dea3e02ec08da12bc8c20779c9f
https://pubmed.ncbi.nlm.nih.gov/28504349
https://pubmed.ncbi.nlm.nih.gov/28504349
Autor:
Sumitra Ramachandran, Angela A. Dunne, Neil Derek Miller, Laiq Chaudry, Vincent Jaquet, Craig Allan, Aleksandra Filippova, Jean Lim, Ceri H. Davies, Agnes B. Ong, May Thu Ma, Shabina Nasir, Woei Shin Chen, Nicole Y. Ye, Edward R. Browne, Kiew Ching K Lee, Shihua Liao, Douglas G. Johns, Angela Bridges, Yasuji Matsuoka, Chiu Cheong Aw, A. Richard Rutter, Adeline L.W. Chueng, Dizheng Li, Deborah W. Chen, Sri Mulyanidewi, Sarah Duncan, Tamara Seredenina, Gary Pettman, Kazufumi Hirano, Pamela P. Oon
Publikováno v:
Antioxidants & redox signaling, Vol. 23, No 5 (2015) pp. 358-374
Aims: The NADPH oxidase (NOX) family of enzymes catalyzes the formation of reactive oxygen species (ROS). NOX enzymes not only have a key role in a variety of physiological processes but also contribute to oxidative stress in certain disease states.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7ea3e136424a97ddab898f120e2665
https://europepmc.org/articles/PMC4545375/
https://europepmc.org/articles/PMC4545375/
Autor:
Jane P. Hughes, Marc G. Wilkinson, Andrew Clarke, Paul S. Carter, Kathrine J. Smith, Alastair D. Reith, Murray J. B. Brown, Angela Bridges, Pete Horrocks, Ceri J. Lewis, Gary Pettman, Benjamin D. Bax
Publikováno v:
Structure. 12(6):1067-1077
Mitogen and stress-activated kinase-1 (MSK1) is a serine/threonine protein kinase that is activated by either p38 or p42ERK MAPKs in response to stress or mitogenic extracellular stimuli. MSK1 belongs to a family of protein kinases that contain two d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927bc89db35f50df90202956f9a2708d
Autor:
Angela Bridges, Benjamin D. Bax, Ainsley A. Culbert, Ceri J. Lewis, Gary Pettman, Smith David Glynn, Paul S. Carter, Murray J. B. Brown, Angela R. Guy, Alastair D. Reith, Chris Mannix, Robert Tanner
Publikováno v:
Structure. 9:1143-1152
Background: Glycogen synthase kinase-3 (GSK-3) sequentially phosphorylates four serine residues on glycogen synthase (GS), in the sequence SxxxSxxxSxxx-SxxxS(p), by recognizing and phosphorylating the first serine in the sequence motif SxxxS(P) (wher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f46b9ec7d3cc4e85aba3d3dd9f3dc3d
https://doi.org/10.1016/s0969-2126(01)00679-7
https://doi.org/10.1016/s0969-2126(01)00679-7
Autor:
Sandra Turconi, Caretha L. Creasy, Robin V. Ward, Eric Karran, Owen Jenkins, Carol W. Gray, Paul S. Carter, Gary Pettman, John Savopoulos
Publikováno v:
Protein Expression and Purification. 19:227-234
HumHtrA2 or Omi is a recently described member of a novel family of mammalian serine proteases homologous to the Escherichia coli htrA gene product. Although the physiological function of members of this new family is unclear, the current understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a797c61b4b5973833accb925a27310db
https://doi.org/10.1006/prep.2000.1240
https://doi.org/10.1006/prep.2000.1240
Autor:
Greg Dean, Diane Hatton, Jessica Stevenson, Gary Pettman, Ray Field, Olalekan Daramola, William Holmes
Publikováno v:
Biotechnology progress. 30(1)
An efficient rapid protein expression system is crucial to support early drug development. Transient gene expression is an effective route, and to facilitate the use of the same host cells as for subsequent stable cell line development, we have creat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bfc0ca8089f93e72e937313845906d1
https://pubmed.ncbi.nlm.nih.gov/24106171
https://pubmed.ncbi.nlm.nih.gov/24106171
Autor:
Frank S. Walsh, David J. Powell, Paul S. Carter, Owen Jenkins, Karen Louise Philpott, John W. Savopoulos, Gary Pettman, David Mills, Carolyn Armour, Stephen Dowd, Catherine J. Greenwood
Publikováno v:
Protein expression and purification. 24(1)
The mitogen-activated protein (MAP) kinases are a group of serine/threonine kinases that mediate intracellular signal transduction in response to environmental stimuli including stress, growth factors, and various cytokines. Of this family, the c-Jun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845f02420829cf76574277745e9d1414
https://pubmed.ncbi.nlm.nih.gov/11812219
https://pubmed.ncbi.nlm.nih.gov/11812219