Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gary Patrick Reid"'
Autor:
Robin Marshall, Catherine Smyth, J. Alf Davis, Alasdair Garnett, Julian Scott Northen, John S. Carey, Stephen J. Byard, Urvish Pandya, Stephen John Martin, Antonio Codina, Gary Patrick Reid, John Mykytiuk, Sophie L. Berrell, Katherine Filer, Lesa Watson
Publikováno v:
Organic Process Research & Development. 23:762-770
This paper describes the process development conducted toward the multi-kilogram synthesis of a hemiadipic acid pro-drug of buprenorphine. The major challenges were to control the levels of the dibuprenorphine monoadipate impurity and to improve the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::878ee5f6f614c4c5a97ffeffdec68649
https://doi.org/10.1021/acs.oprd.9b00025
https://doi.org/10.1021/acs.oprd.9b00025
Autor:
Colin Hogg, Julian Northern, Michael Reader, Christopher N. Johnson, Alistair Meek, Martyn Frederickson, Gary Patrick Reid, James Edward Harvey Day
Publikováno v:
Synlett. 26:2570-2574
A range of azaindolines was prepared in three steps from heterocyclic amines using halogenation, alkylation with 3-bromo-2-methylpropene, and a palladium-catalysed reductive cyclisation. The chemistry proved applicable to a multigram-scale operation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34fe23c859b7470e4223a544347aa8d3
https://doi.org/10.1055/s-0035-1560320
https://doi.org/10.1055/s-0035-1560320
Autor:
Thomas McInally, Darren S. Lee, Steve Brough, Zacharias Amara, Thomas Harman, Martyn Poliakoff, Barrie Rhodes, Gary Patrick Reid, Simon Woodward
Publikováno v:
Organic Process Research & Development. 19:831-840
Methods for the batch scale up of DABAL-Me3 promoted direct ester to amide synthesis have been demonstrated at 10–100 g scales using a tert-amide model compound. Procedures for 20 g scale couplings in standard laboratory glassware and up to 0.1 kg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e97653002cabae39d093938ce73c8953
https://doi.org/10.1021/acs.oprd.5b00101
https://doi.org/10.1021/acs.oprd.5b00101
Autor:
Christopher N. Johnson, Julian Northern, Alistair Meek, Gary Patrick Reid, Michael Reader, Colin Hogg, Martyn Frederickson, James Edward Harvey Day
Publikováno v:
ChemInform. 47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9913f8537908596d7078ce7f47034f53
https://doi.org/10.1002/chin.201613037
https://doi.org/10.1002/chin.201613037
Autor:
Martyn Poliakoff, Zacharias Amara, Thomas Harman, Simon Woodward, Barrie Rhodes, Steve Brough, Gary Patrick Reid, Thomas McInally, Darren S. Lee
Publikováno v:
ChemInform. 46
Methods for the batch scale up of DABAL-Me3 promoted direct ester to amide synthesis have been demonstrated at 10–100 g scales using a tert-amide model compound. Procedures for 20 g scale couplings in standard laboratory glassware and up to 0.1 kg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3355ded6bc19fec32a9f6dd9008a5599
https://doi.org/10.1002/chin.201547090
https://doi.org/10.1002/chin.201547090
Publikováno v:
Tetrahedron: Asymmetry. 15:793-801
Conjugate addition of Grignard reagents to N,N′-fumaroylbis[(2R)-bornane-10,2-sultam] 1 occurred with moderate to high levels of diastereoselectivity. Diastereomeric excesses were estimated by analysis of the 1H NMR spectra of the succinamide mixtu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b7161a993cc67ec0e3558b17354ca44
https://doi.org/10.1016/j.tetasy.2003.12.010
https://doi.org/10.1016/j.tetasy.2003.12.010