Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gary P. Watters"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Atherosclerosis is a complex process involving progressive pathological events, including monocyte adhesion to the luminal endothelial surface. We have developed a functional in vitro adhesion assay using BioFlux microfluidic technology to i
Externí odkaz:
https://doaj.org/article/2bff10ca82594bb2a0a8f3cd115024d0
Publikováno v:
Journal of Nucleic Acids, Vol 2010 (2010)
The role of topoisomerase IIβ was investigated in cell lines exposed to two DNA damaging agents, ionising radiation (IR) or etoposide, a drug which acts on topoisomerase II. The appearance and resolution of γH2AX foci in murine embryonic fibroblast
Externí odkaz:
https://doaj.org/article/e0215dca65734e43a08a095cc6106d09
Autor:
Sarah Phillips, Victoria Hargreaves, Gary P. Watters, Teresa Chirom, Julie Clements, Robert Smith, James Whitwell, Mel Lloyd
Publikováno v:
Mutagenesis. 34:217-237
The in vitro micronucleus (IVMN) test was endorsed for regulatory genotoxicity testing with adoption of the Organisation for Economic Co-operation and Development (OECD) test guideline (TG) 487 in 2010. This included two equally acceptable options fo
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Atherosclerosis is a complex process involving progressive pathological events, including monocyte adhesion to the luminal endothelial surface. We have developed a functional in vitro adhesion assay using BioFlux microfluidic technology to investigat
Autor:
Damien Breheny, Gina A. Smith, Gary P. Watters, Hannah Flockton, W. Fields, O. Makwana, Frazer Lowe
Publikováno v:
Science meets clinical practice.
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 58
Chronic exposure to cigarette smoke can lead to endothelial dysfunction and potentially endothelial cell death. Here, we exposed Human Aortic Endothelial Cells (HAECs) to whole smoke conditioned media (WSCM) over a range of nicotine equivalence (n.e.
Autor:
Om Makwana, Wanda R. Fields, Gina A. Smith, Hannah Flockton, Betsy Bombick, Gary P. Watters, Rizwan Nisar
Publikováno v:
Alternatives to laboratory animals : ATLA. 45(4)
Although chronic progressive cardiovascular diseases such as atherosclerosis are often challenging to fully model in vitro, it has been shown that certain in vitro methods can effectively evaluate some aspects of disease progression. This has been de