Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gary P. Dowthwaite"'
Autor:
Rebecca Williams, Ilyas M Khan, Kirsty Richardson, Larissa Nelson, Helen E McCarthy, Talal Analbelsi, Sim K Singhrao, Gary P Dowthwaite, Rhiannon E Jones, Duncan M Baird, Holly Lewis, Selwyn Roberts, Hannah M Shaw, Jayesh Dudhia, John Fairclough, Timothy Briggs, Charles W Archer
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13246 (2010)
BackgroundArticular cartilage displays a poor repair capacity. The aim of cell-based therapies for cartilage defects is to repair damaged joint surfaces with a functional replacement tissue. Currently, chondrocytes removed from a healthy region of th
Externí odkaz:
https://doaj.org/article/5d9c1dff7d2e4706b3841b4a41b1b7c7
Autor:
Rosemary F L, Suswillo, Behzad, Javaheri, Simon C F, Rawlinson, Gary P, Dowthwaite, Lance E, Lanyon, Andrew A, Pitsillides
Publikováno v:
Cell Biochemistry and Function
Identifying mechanisms by which cells of the osteoblastic lineage communicate in vivo is complicated by the mineralised matrix that encases osteocytes, and thus, vital mechanoadaptive processes used to achieve load-bearing integrity remain unresolved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ae889f4c1f44f2f15d2761febd80d54b
http://europepmc.org/articles/PMC5299599
http://europepmc.org/articles/PMC5299599
Publikováno v:
Journal of Anatomy. 215:159-169
The development of limb cartilage involves complex signalling pathways allowing the formation of distinct segments of cartilage that are maintained in the fully developed joint. In this study, we investigated the Notch signalling pathway and its role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c0d261a01f451952e94100fe2e9a46
https://doi.org/10.1111/j.1469-7580.2009.01089.x
https://doi.org/10.1111/j.1469-7580.2009.01089.x
Autor:
Ilyas M. Khan, Gary P. Dowthwaite, James Robert Ralphs, W. Terence Coakley, Charles W. Archer, Despina Bazou
Publikováno v:
Molecular Membrane Biology. 23:195-205
Particles or cells suspended in an appropriately designed ultrasound standing wave field can be aggregated at a node to form a single monolayer in a plane that can be interrogated microscopically. The approach is applied here to investigate the tempo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84bbdf9cbff1844d185ba48c942070f
https://doi.org/10.1080/09687860600555906
https://doi.org/10.1080/09687860600555906
Autor:
Rosemary F. L. Suswillo, Gary P. Dowthwaite, Simon C.F. Rawlinson, Andrew A. Pitsillides, Behzad Javaheri, Lance E. Lanyon
Publikováno v:
Cell Biochemistry and Function. 35:244-244
Biotechnology and Biological Sciences Research Council BB/I014608/1, Arthritis Research UK 20413, 20581, 20039.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53332e33b95fbba0e538bf9c8cd82579
https://doi.org/10.1002/cbf.3268
https://doi.org/10.1002/cbf.3268
Publikováno v:
Journal of Histochemistry & Cytochemistry. 46:641-651
We studied the expression of hyaluronan binding proteins (HABPs) during the development of embryonic chick joints, using immunocytochemistry and biotinylated HA. The expression of actin capping proteins and of actin itself was also studied because th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8ac71cbe73b6db6bbd09ae24e88234
https://doi.org/10.1177/002215549804600509
https://doi.org/10.1177/002215549804600509
Autor:
Ilyas M. Khan, Laura Haughton, Charles W. Archer, S. F. Oldfield, Samantha Redman, James Robert Ralphs, Gary P. Dowthwaite
Publikováno v:
Culture of Human Stem Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56d829455580530adea6453ff5dfab33
https://doi.org/10.1002/9780470167526.ch10
https://doi.org/10.1002/9780470167526.ch10
Autor:
S. F. Oldfield, Charles W. Archer, Gary P. Dowthwaite, Ilyas M. Khan, Rebecca Williams, Samantha Redman
During vertebrate evolution, successful adaptation of animal limbs to a variety of ecological niches depended largely on the formation and positioning of synovial joints. The function of a joint is to allow smooth articulation between opposing skelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f88c6f734cb29f5906fcfd7aa54db33
https://doi.org/10.1016/s0070-2153(06)79001-9
https://doi.org/10.1016/s0070-2153(06)79001-9
Autor:
Joanna Bishop, Charles W. Archer, Paul Rooney, Sam Boyer, Zubeyde Bayram, Michael S. Wolfe, Brian Mark Thomson, Laura Haughton, Gary P. Dowthwaite, Ilyas M. Khan, Samantha Redman, Darrell J. R. Evans
Publikováno v:
Journal of cell science. 117(Pt 6)
It is becoming increasingly apparent that articular cartilage growth is achieved by apposition from the articular surface. For such a mechanism to occur, a population of stem/progenitor cells must reside within the articular cartilage to provide tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a15416417a77d23129e3327acac2c9
https://pubmed.ncbi.nlm.nih.gov/14762107
https://pubmed.ncbi.nlm.nih.gov/14762107
Publikováno v:
Birth defects research. Part C, Embryo today : reviews. 69(2)
Synovial joints arise through two main processes. In long bone elements, cartilaginous differentiation occurs across the locations of the prospective joints that then segment secondarily. This process occurs through the development of a noncartilagin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8615e6223bc56c3b0964dcb4264e1c14
https://pubmed.ncbi.nlm.nih.gov/12955858
https://pubmed.ncbi.nlm.nih.gov/12955858