Gene expression patterns in larval Schistosoma mansoni associated with infection of the mammalian host.

Autor: Sophia J Parker-Manuel, Alasdair C Ivens, Gary P Dillon, R Alan Wilson

Publikováno v: PLoS Neglected Tropical Diseases, Vol 5, Iss 8, p e1274 (2011)

The infective schistosome cercaria develops within the intramolluscan daughter sporocyst from an undifferentiated germ ball, during which synthesis of proteins essential for infection occurs. When the aquatic cercaria locates the mammalian host it ra

Externí odkaz: https://doaj.org/article/e5d8acbef1564b978b98b9f6a1d5cb70

Altered patterns of gene expression underlying the enhanced immunogenicity of radiation-attenuated schistosomes.

Autor: Gary P Dillon, Theresa Feltwell, Jason Skelton, Patricia S Coulson, R Alan Wilson, Alasdair C Ivens

Publikováno v: PLoS Neglected Tropical Diseases, Vol 2, Iss 5, p e240 (2008)

Schistosome cercariae only elicit high levels of protective immunity against a challenge infection if they are optimally attenuated by exposure to ionising radiation that truncates their migration in the lungs. However, the underlying molecular mecha

Externí odkaz: https://doaj.org/article/fcbd7385125045babb1faa090f7c187a

Schistosome albumin is of host, not parasite, origin

Autor: William Mathieson, R. Alan Wilson, Gary P. Dillon, Ricardo DeMarco

Publikováno v: International Journal for Parasitology. 37:1201-1208

Recent work has implicated schistosome albumin as part of a mechanism for neutralizing the oxidative assault by host immune defenses and suggested that the gene had been acquired by horizontal transfer from the mammalian host. In the course of proteo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e08980f828c948c32ab99b5bd1c1312
https://doi.org/10.1016/j.ijpara.2007.03.004

‘Oming in on schistosomes: prospects and limitations for post-genomics

Autor: Gary P. Dillon, Alasdair Ivens, Simon Braschi, Peter D. Ashton, R. Alan Wilson, Matthew Berriman

Publikováno v: Trends in Parasitology. 23:14-20

The recent release of version 3 of the Schistosoma mansoni genome assembly has made a wealth of information available to researchers. Here, progress made in schistosome genomics and post-genomics is considered. The current status of knowledge about t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2365704a6cc25b85b9ddefca76b0eb9f
https://doi.org/10.1016/j.pt.2006.10.002

A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni

Autor: Richard Clark, Martin Hunt, Jacquelline McQuillan, Claire Davidson, Guilherme Oliveira, Tim J. Anderson, Sophia J. Parker-Manuel, Nishadi De Silva, Sarah Nichol, Philip T. LoVerde, Martin Aslett, David W. Dunne, Giles S. Velarde, Nancy Holroyd, Anna V. Protasio, Adhemar Zerlotini, Michael A. Quail, Gary P. Dillon, Thomas D. Otto, A K Babbage, R. Alan Wilson, Christine Lloyd, Isheng J. Tsai, Matthew Berriman

Publikováno v: PLoS Neglected Tropical Diseases, Vol 6, Iss 1, p e1455 (2012)
PLoS Neglected Tropical Diseases
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice)
Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA

Schistosomiasis is one of the most prevalent parasitic diseases, affecting millions of people in developing countries. Amongst the human-infective species, Schistosoma mansoni is also the most commonly used in the laboratory and here we present the s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f36a3a97c40d24f8d1907739f5811f
http://europepmc.org/articles/PMC3254664?pdf=render