Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gary P. Adams"'
Autor:
Richard B. Gillis, Hodaya V. Solomon, Lata Govada, Neil J. Oldham, Vlad Dinu, Shahwar Imran Jiwani, Philemon Gyasi-Antwi, Frank Coffey, Andy Meal, Paul S. Morgan, Stephen E. Harding, John R. Helliwell, Naomi E. Chayen, Gary G. Adams
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract This study concerns glulisine, a rapid-acting insulin analogue that plays a fundamental role in diabetes management. We have applied a combination of methods namely X-ray crystallography, and biophysical characterisation to provide a detaile
Externí odkaz:
https://doaj.org/article/1baf07d48a3740889f7ac839d941f0d3
Autor:
Gary G. Adams, Qushmua Alzahrani, Shahwar I. Jiwani, Andrew Meal, Paul S. Morgan, Frank Coffey, Samil Kok, Arthur J. Rowe, Stephen E. Harding, Naomi Chayen, Richard B. Gillis
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Single, double and triple doses of the synthetic insulins glargine and degludec currently used in patient therapy are characterised using macromolecular hydrodynamic techniques (dynamic light scattering and analytical ultracentrifugation) in
Externí odkaz:
https://doaj.org/article/b78d16e655964b44a202114d783230a1
Autor:
Gary G Adams, Andrew Meal, Paul S Morgan, Qushmua E Alzahrani, Hanne Zobel, Ryan Lithgo, M Samil Kok, David T M Besong, Shahwar I Jiwani, Simon Ballance, Stephen E Harding, Naomi Chayen, Richard B Gillis
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0195010 (2018)
The structure and function of clinical dosage insulin and its analogues were assessed. This included 'native insulins' (human recombinant, bovine, porcine), 'fast-acting analogues' (aspart, glulisine, lispro) and 'slow-acting analogues' (glargine, de
Externí odkaz:
https://doaj.org/article/6f88f3f9db90488b922c9a3749e8fc14
Autor:
Stephen E. Harding, Richard B. Gillis, Fahad Almutairi, Tayyibe Erten, M. Şamil Kök, Gary G. Adams
Publikováno v:
Biology, Vol 4, Iss 1, Pp 237-250 (2015)
Sedimentation in the analytical ultracentrifuge is a matrix free solution technique with no immobilisation, columns, or membranes required and can be used to study self-association and complex or “hetero”-interactions, stoichiometry, reversibilit
Externí odkaz:
https://doaj.org/article/0a6e0a8c36904919811024e3fda7c391
Autor:
George Kerrison, Richard B. Gillis, Shahwar I. Jiwani, Qushmua Alzahrani, Samil Kok, Stephen E. Harding, Ian Shaw, Gary G. Adams
Publikováno v:
Journal of Diabetes Research, Vol 2017 (2017)
Diabetes prevalence is increasing exceptionally worldwide and with this come associated healthcare costs. The primary outcome of this systematic review was to assess glycaemic control and incidence of Type 2 diabetes mellitus (T2DM) diagnosis after e
Externí odkaz:
https://doaj.org/article/99160720a02545a9901ea2f56e1ec573
Publikováno v:
Crystals, Vol 9, Iss 9, p 462 (2019)
Glulisine is a US Food and Drug Administration (FDA) approved insulin analogue, used for controlling hyperglycaemia in patients with diabetes mellitus (DM). It is fast acting which better approximates physiological insulin secretion, improving patien
Externí odkaz:
https://doaj.org/article/974537393fd142aa94492ecf1ff8f1a1
Autor:
Theo Varzakas, Asma Alghamdi, Hanan Alghamdi, Robert Linforth, Vlad Dinu, Tabot D. Besong, Richard B. Gillis, Gary G. Adams, D. Arapoglou, Ian F. Connerton, Stephen E. Harding, Cleanthes Israilides
Publikováno v:
Cogent Food & Agriculture, Vol 2, Iss 1 (2016)
Starches from three organically produced cultivars of potato tuber (Lady Rosetta, Spunta and Voyager) have been studied in relation to (i) acrylamide production (ii) macromolecular integrity after frying with extra virgin olive oil, soybean oil and c
Externí odkaz:
https://doaj.org/article/a17b4984eafe4c82962915a7e33744b6
Autor:
Gary P. Adams, Robert D. McDonald, Richard John Weiland, Lisa Michelle Wills, Terry C. Rooney
Publikováno v:
All Days.
Abstract Salt diapirism to very shallow depths below seabed in the deepwater Gulf of Mexico Puma appraisal area has extensively tilted, thinned and faulted supra-salt strata, and permitted the migration of asphalt, oil and gas to the seafloor and int