Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Gary M. Wildey"'
Autor:
Gary M. Wildey, Philip H. Howe
Publikováno v:
Journal of Biological Chemistry. 284:20227-20239
Transforming growth factor beta (TGFbeta) regulates essential cellular functions such as cellular proliferation, differentiation, and apoptosis. The Bcl-2 family of proteins has been implicated as mediators of TGFbeta-induced apoptosis. We demonstrat
Publikováno v:
Cell Cycle. 8:11-17
Transforming growth factor beta (TGFbeta) regulates essential cellular functions such as cellular proliferation, differentiation and apoptosis. Multiple apoptotic mediators and signaling pathways have been implicated in TGFbeta-induced apoptosis. Bim
Autor:
Lianfu Wang, Gary M. Wildey, Horng Ren Yang, Guoping Jiang, John J. Fung, Shiguang Qian, Lina Lu
Publikováno v:
Transplantation. 86:1492-1502
Organ transplantation has been successfully practiced for decades, but the outcome of cell transplantation remains disappointing. This is the case in animal models; liver allografts in mice are spontaneously accepted without requirement of immunosupp
Publikováno v:
Journal of Biological Chemistry. 281:813-823
Bim, the Bcl-2 interacting mediator of cell death, is a member of the BH3-only family of pro-apoptotic proteins. Recent studies have demonstrated that the apoptotic activity of Bim can be regulated through a post-translational mechanism whereby ERK p
Publikováno v:
Journal of Biological Chemistry. 278:18069-18077
Transforming growth factor-beta (TGFbeta) is a potent growth inhibitor and inducer of apoptosis in B lymphocytes and is essential for immune regulation and maintenance of self-tolerance. Here we show that exogenous overexpression of Smad3 potentiates
Autor:
Gary M. Wildey, Philip H. Howe
Publikováno v:
Atlas of Genetics and Cytogenetics in Oncology and Haematology.
Autor:
John J. Letterio, Gary M. Wildey, Jeffery D. Molkentin, Xiao Jun Qi, Philip H. Howe, Sneha Ramesh, Janet Robinson
Publikováno v:
EMBO reports. 9(10)
Transforming growth factor-beta (TGFbeta) induces the expression of the pro-apoptotic protein BIM, and mediates apoptosis in hepatocytes and B lymphocytes. BIM is regulated through a post-translational mechanism involving ERK-dependent phosphorylatio
Publikováno v:
Journal of biomedical materials research. Part A. 67(2)
The extracellular matrices of connective tissues contain growth factors such as transforming growth factor (TGF)-beta1. The possibility arises, therefore, that animal connective tissues that have been excised and rendered acellular in the sterilizati
Publikováno v:
The Journal of biological chemistry. 275(49)
Transforming growth factor-beta (TGF-beta) is a potent inducer of apoptosis in B-lymphocytes and is essential for immune regulation and maintenance of self-tolerance. Here we show that concomitant signaling through CD40 sustains proliferation and res
Detection of low molecular weight GTP-binding proteins associated with rat atrial secretory granules
Autor:
Albert E. Matyas, Gary M. Wildey
Publikováno v:
Journal of molecular and cellular cardiology. 25(4)
Recent studies suggest that low molecular weight (LMW) GTP-binding proteins are involved in the vesicular transport of proteins along the secretory pathway. In order to determine whether LMW GTP-binding proteins are potentially involved in the regula