Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Gary M. Skinner"'
Autor:
Alfred J. Meixner, Maxime Dahan, Brahim Lounis, Felix Koberling, W. E. Moerner, Alex S. Clark, Paul W. Bohn, Himangshu Prabal Goswami, Sanli Faez, Francisco Balzarotti, Jens Michaelis, Xin Shi, Thorben Cordes, Gary M. Skinner, Lisa-Maria Needham, Ana Peñaherrera, Sergey Sekatskii, Arindam Chowdhury, Victoria Birkedal, Niek F. van Hulst, Lukas Novotny, Michel Orrit, Lukasz Piatkowski, Phil Williams, Wolfgang Werner Langbein, Vahid Sandoghdar
Publikováno v:
Cordes, T, Moerner, W, Orrit, M, Needham, L-M, Sekatskii, S, Faez, S, Goswami, H, Clark, A, Meixner, A, Piatkowski, L, Sandoghar, V, Skinner, G, Balzarotti, F, Langbein, W, Novotny, L, Birkedal, V, Koberling, F, Michaelis, J, Williams, P, Chowdhury, A, van Hulst, N, Dahan, M, Penaherrera, A, Lounis, B, Bohn, P W & Shi, X 2015, ' Supersolution techniques, biophysics with nanostructures, and fluorescence energy transfer: general discussion ', Faraday Discussions, vol. 184, pp. 143-162 . https://doi.org/10.1039/C5FD90094H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dcc91b551d58ce1b909593da7ef7f44
https://doi.org/10.1039/c5fd90094h
https://doi.org/10.1039/c5fd90094h
A simple DNA-based data storage scheme is demonstrated in which information is written using "addressing" oligonucleotides. In contrast to other methods that allow arbitrary code to be stored, the resulting DNA is suitable for downstream enzymatic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240d8283d7c489ed234ae932e5b1726d
Autor:
Zhongbo Yu, Gary M. Skinner, Johannes M. Keegstra, Jan Lipfert, Mariana Köber, Serge Donkers, Nynke H. Dekker, Fang-Chieh Chou, Rhiju Das, Toivo Hensgens, Tessa Jager, David Dulin
Publikováno v:
Proceedings of the National Academy of Sciences. 111:15408-15413
RNA plays myriad roles in the transmission and regulation of genetic information that are fundamentally constrained by its mechanical properties, including the elasticity and conformational transitions of the double-stranded (dsRNA) form. Although do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9b471310f306b95ca4e65b3abcd287
https://doi.org/10.1073/pnas.1407197111
https://doi.org/10.1073/pnas.1407197111
Autor:
Gary M. Skinner, Koen Visscher
Publikováno v:
ASSAY and Drug Development Technologies. 2:397-406
Single-molecule techniques offer a number of key benefits over conventional in vitro assay methods for drug screening, as they use less material and unlock the ability to observe transient states. By observing such states, it should be possible to sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa2c2a0bd43bd7347d62217d27d3d67
https://doi.org/10.1089/adt.2004.2.397
https://doi.org/10.1089/adt.2004.2.397
Publikováno v:
Journal of Biological Chemistry. 279:3239-3244
A single-molecule transcription assay has been developed that allows, for the first time, the direct observation of promoter binding, initiation, and elongation by a single RNA polymerase (RNAP) molecule in real-time. To promote DNA binding and trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e11c101ae0709ae2c07541892c3b3c88
https://doi.org/10.1074/jbc.m310471200
https://doi.org/10.1074/jbc.m310471200
Autor:
Stephanie Allen, Justin E. Molloy, S. J. B. Tendler, Ingrid Tessmer, Christoph G. Baumann, James G. Hoggett, Gary M. Skinner
Publikováno v:
Journal of Modern Optics. 50:1627-1636
Optical tweezers were employed to investigate the effects of small DNA-binding molecules on the low-force (≤ 15 pN) stretching behaviour of single DNA molecules. As the canonical B-DNA helix is not perturbed in this force regime, the effects on DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b1cdf62c120c67ceaaae1b5463f3492
https://doi.org/10.1080/09500340308235236
https://doi.org/10.1080/09500340308235236
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 7(15)
Solid-state nanopores are widely acknowledged as tools with which to study local structure in biological molecules. Individual molecules are forced through a nanopore, causing a characteristic change in an ionic current that depends on the molecules'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5334428b816fd2de1bc6d062008533
https://pubmed.ncbi.nlm.nih.gov/21638785
https://pubmed.ncbi.nlm.nih.gov/21638785
Publikováno v:
Biophysical Journal. 98(3)
Through a novel "polymerase-stall" labeling procedure, we have successfully generated torsionally constrained molecules of double-stranded RNA (dsRNA). We have anchored these molecules within a magnetic tweezers apparatus, and by rotating the magnets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56e3b7ce482410de641a758c83a4a03
Publikováno v:
SPIE Proceedings.
To access the genetic code to be transcribed to RNA, RNA polymerases must first open a “transcription bubble” in the DNA. Structural studies suggest that the minimal model of initiation by T7 bacterophage RNA polymerase (T7 RNAP) consists of two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57dce05e9144a51b94d5138465bc83a3
https://doi.org/10.1117/12.827659
https://doi.org/10.1117/12.827659
Publikováno v:
Nano letters. 9(8)
Solid-state nanopores offer a promising method for rapidly probing the structural properties of biopolymers such as DNA and RNA. We have for the first time translocated RNA molecules through solid-state nanopores, comparing the signatures of transloc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6502229fd00242dd06034ad20d3fe3
https://pubmed.ncbi.nlm.nih.gov/19537802
https://pubmed.ncbi.nlm.nih.gov/19537802