Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Gary M, Winslow"'
Autor:
Russell C. Levack, Krista L. Newell, Berenice Cabrera-Martinez, Justin Cox, Andras Perl, Sheldon I. Bastacky, Gary M. Winslow
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
CD11c+T-bet+ B cells have been linked with different autoimmune diseases, but targeting these cells has been challenging. Here the authors use an adenosine 2A receptor agonist to deplete these B cells and to inhibit or reverse autoimmune symptoms and
Externí odkaz:
https://doaj.org/article/ad1d117384734ced8d0988ad19e62902
Autor:
Krista L Newell, Deanna C Clemmer, Justin B Cox, Yetunde I Kayode, Victoria Zoccoli-Rodriguez, Harry E Taylor, Timothy P Endy, Joel R Wilmore, Gary M Winslow
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244855 (2021)
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the pandemic human respiratory illness COVID-19, is a global health emergency. While severe acute disease has been linked to an expansion of antibody-secreting plasm
Externí odkaz:
https://doaj.org/article/a3f40b7299e742eb8d75247c785c9310
Publikováno v:
The Journal of Immunology. 208:2749-2760
T-bet+ B cells have emerged as a major B cell subset associated with both protective immunity and immunopathogenesis. T-bet is a transcription factor associated with the type I adaptive immune response to intracellular pathogens, driving an effector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3d3d08b88919541650d02b43352fd12
https://doi.org/10.4049/jimmunol.2101209
https://doi.org/10.4049/jimmunol.2101209
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178853 (2017)
IgM memory cells are recognized as an important component of B cell memory in mice and humans. Our studies of B cells elicited in response to ehrlichial infection identified a population of CD11c-positive IgM memory cells, and an IgM bone marrow anti
Externí odkaz:
https://doaj.org/article/567afab8254c4125aae40db140b6143c
Autor:
Krista L. Newell, Berenice Cabrera-Martinez, Gary M. Winslow, Maria Popescu, Russell C. Levack
Publikováno v:
The Journal of Immunology. 205:1050-1058
CD11c+ T-bet+ B cells generated during ehrlichial infection require CD4+ T cell help and IL-21 signaling for their development, but the exact T cell subset required had not been known. In this study, we show in a mouse model of Ehrlichia muris that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd1edba99fad59e81603d46626b9aa21
https://doi.org/10.4049/jimmunol.2000206
https://doi.org/10.4049/jimmunol.2000206
Publikováno v:
J Immunol
T-bet(+) B cells have emerged as a major B cell subset associated with both protective immunity and immunopathogenesis. T-bet is a transcription factor associated with type I adaptive immune response to intracellular pathogens, driving an effector pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fdcd1618d7ee46f58a9277ac147b21a
https://pubmed.ncbi.nlm.nih.gov/35867676
https://pubmed.ncbi.nlm.nih.gov/35867676
Autor:
Justin B. Cox, Victoria Zoccoli-Rodriguez, Krista L. Newell, Gary M. Winslow, Harry E. Taylor, Timothy P. Endy, Yetunde I. Kayode, Joel R. Wilmore, Deanna C. Clemmer
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244855 (2021)
medRxiv
PLoS ONE
medRxiv
PLoS ONE
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the pandemic human respiratory illness COVID-19, is a global health emergency. While severe acute disease has been linked to an expansion of antibody-secreting plasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d968c01acd209849109d9321f292ff
https://doaj.org/article/a3f40b7299e742eb8d75247c785c9310
https://doaj.org/article/a3f40b7299e742eb8d75247c785c9310
Autor:
Russell C, Levack, Krista L, Newell, Berenice, Cabrera-Martinez, Justin, Cox, Andras, Perl, Sheldon I, Bastacky, Gary M, Winslow
Publikováno v:
Nature Communications
CD11c+T-bet+ B cells are recognized as an important component of humoral immunity and autoimmunity. These cells can be distinguished from other B cells by their higher expression of the adenosine receptor 2a. Here we address whether A2A receptor acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5da815c40ee32b072be0ec6d7ba6704e
https://pubmed.ncbi.nlm.nih.gov/35064115
https://pubmed.ncbi.nlm.nih.gov/35064115
Autor:
Russell C, Levack, Krista L, Newell, Maria, Popescu, Berenice, Cabrera-Martinez, Gary M, Winslow
Publikováno v:
J Immunol
CD11c+ T-bet+ B cells generated during ehrlichial infection require CD4+ T cell help and IL-21 signaling for their development, but the exact T cell subset required had not been known. Here we show, in a mouse model of Ehrlichia muris, that T(FH1) ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a07c58929511c25649034b7e56da143
https://pubmed.ncbi.nlm.nih.gov/32680956
https://pubmed.ncbi.nlm.nih.gov/32680956
Autor:
Thangam Sudha Velayutham, Sandeep Kumar, Nurgun Kose, Jere W. McBride, James E. Crowe, Gary M. Winslow, Xiaofeng Zhang, David H. Walker
Publikováno v:
Infection and Immunity
Antibodies are essential for immunity against Ehrlichia chaffeensis, and protective mechanisms involve blocking of ehrlichial attachment or complement and Fcγ-receptor-dependent destruction. In this study, we determined that major outer membrane pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c60edfe1186c65f0dd7d7d0716ba94
https://doi.org/10.1128/iai.00383-19
https://doi.org/10.1128/iai.00383-19